D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 48 Citations 23,771 80 World Ranking 3523 National Ranking 246

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Enzyme
  • Immune system

Her primary areas of study are Cell biology, T cell, Signal transduction, Biochemistry and Cellular differentiation. Her Cell biology study combines topics from a wide range of disciplines, such as CD8, Immune system, Immunity, Metabolic pathway and Cytotoxic T cell. Her T cell study combines topics in areas such as Glycolysis, Anaerobic glycolysis and Oxidative phosphorylation.

Her study focuses on the intersection of Anaerobic glycolysis and fields such as Cell with connections in the field of Mitochondrion and Beta oxidation. Her Signal transduction research integrates issues from Golgi apparatus, Endoplasmic reticulum and Secretion. Her studies in Cellular differentiation integrate themes in fields like Lymphocyte and Effector.

Her most cited work include:

  • Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens (1142 citations)
  • Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression (1132 citations)
  • Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis (1078 citations)

What are the main themes of her work throughout her whole career to date?

Her primary areas of investigation include Cell biology, T cell, Immune system, Cytotoxic T cell and Biochemistry. The various areas that she examines in her Cell biology study include Oxidative phosphorylation, Cellular differentiation and Metabolism. Erika L. Pearce interconnects Glycolysis, Anaerobic glycolysis, Interleukin 4 and Cellular respiration in the investigation of issues within Oxidative phosphorylation.

Her research investigates the connection with T cell and areas like Effector which intersect with concerns in Cell growth. Her Immune system study integrates concerns from other disciplines, such as Cancer and Antigen. Her Cytotoxic T cell research includes elements of CD8 and Virology.

She most often published in these fields:

  • Cell biology (67.27%)
  • T cell (37.27%)
  • Immune system (32.73%)

What were the highlights of her more recent work (between 2019-2021)?

  • Cell biology (67.27%)
  • T cell (37.27%)
  • Immune system (32.73%)

In recent papers she was focusing on the following fields of study:

Her scientific interests lie mostly in Cell biology, T cell, Immune system, Cell and Cancer research. The concepts of her Cell biology study are interwoven with issues in Macrophage, Cytokine and Metabolism. Her biological study spans a wide range of topics, including Human disease, Computational biology, CRISPR and In vivo.

Her studies deal with areas such as Cancer and Tumor progression as well as Immune system. Her Cell research incorporates elements of Host and Effector. To a larger extent, Erika L. Pearce studies Biochemistry with the aim of understanding Cytotoxic T cell.

Between 2019 and 2021, her most popular works were:

  • Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function (54 citations)
  • Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity (54 citations)
  • Triacylglycerol synthesis enhances macrophage inflammatory function. (20 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Immune system

Erika L. Pearce mostly deals with Cell biology, Effector, Cell, Glycolysis and T cell. Her research in Cell biology intersects with topics in Experimental autoimmune encephalomyelitis, Immune system, Cytokine and PKM2. The Effector study combines topics in areas such as Cell therapy and Dysbiosis.

Her Glycolysis research is multidisciplinary, incorporating perspectives in Leukemia, Myeloid leukemia, Intracellular pH and Transplantation. Her T cell study combines topics in areas such as Transcriptome, Polyamine and FOXP3. Her studies deal with areas such as Tumor microenvironment, Function, Protein biosynthesis, Fatty acid-binding protein and Metabolism as well as Intracellular.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

Chih Hao Chang;Jing Qiu;David O'Sullivan;Michael D. Buck.
Cell (2015)

1869 Citations

Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens

Matthew M. Gubin;Xiuli Zhang;Heiko Schuster;Etienne Caron.
Nature (2014)

1776 Citations

Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis

Chih-Hao Chang;Jonathan D. Curtis;Leonard B. Maggi;Brandon Faubert.
Cell (2013)

1636 Citations

Enhancing CD8 T-cell memory by modulating fatty acid metabolism.

Erika L. Pearce;Matthew C. Walsh;Pedro J. Cejas;Gretchen M. Harms.
Nature (2009)

1414 Citations

Metabolic Pathways in Immune Cell Activation and Quiescence

Erika L. Pearce;Edward J. Pearce.
Immunity (2013)

1244 Citations

Mitochondrial Respiratory Capacity Is a Critical Regulator of CD8+ T Cell Memory Development

Gerritje J.W. van der Windt;Bart Everts;Chih-Hao Chang;Jonathan D. Curtis.
Immunity (2012)

1212 Citations

Control of Effector CD8+ T Cell Function by the Transcription Factor Eomesodermin

Erika L. Pearce;Alan C. Mullen;Gislâine A. Martins;Connie M. Krawczyk.
Science (2003)

1095 Citations

Fueling immunity: insights into metabolism and lymphocyte function.

Erika L. Pearce;Maya C. Poffenberger;Chih-Hao Chang;Russell G. Jones.
Science (2013)

1086 Citations

Mitochondrial Dynamics Controls T Cell Fate Through Metabolic Programming

Michael D D. Buck;Michael D D. Buck;David O'Sullivan;Ramon I I. Klein Geltink;Jonathan D D. Curtis.
Cell (2016)

913 Citations

T cell metabolism drives immunity

Michael D. Buck;David O’Sullivan;Erika L. Pearce.
Journal of Experimental Medicine (2015)

902 Citations

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