Her primary areas of study are Cell biology, T cell, Signal transduction, Biochemistry and Cellular differentiation. Her Cell biology study combines topics from a wide range of disciplines, such as CD8, Immune system, Immunity, Metabolic pathway and Cytotoxic T cell. Her T cell study combines topics in areas such as Glycolysis, Anaerobic glycolysis and Oxidative phosphorylation.
Her study focuses on the intersection of Anaerobic glycolysis and fields such as Cell with connections in the field of Mitochondrion and Beta oxidation. Her Signal transduction research integrates issues from Golgi apparatus, Endoplasmic reticulum and Secretion. Her studies in Cellular differentiation integrate themes in fields like Lymphocyte and Effector.
Her primary areas of investigation include Cell biology, T cell, Immune system, Cytotoxic T cell and Biochemistry. The various areas that she examines in her Cell biology study include Oxidative phosphorylation, Cellular differentiation and Metabolism. Erika L. Pearce interconnects Glycolysis, Anaerobic glycolysis, Interleukin 4 and Cellular respiration in the investigation of issues within Oxidative phosphorylation.
Her research investigates the connection with T cell and areas like Effector which intersect with concerns in Cell growth. Her Immune system study integrates concerns from other disciplines, such as Cancer and Antigen. Her Cytotoxic T cell research includes elements of CD8 and Virology.
Her scientific interests lie mostly in Cell biology, T cell, Immune system, Cell and Cancer research. The concepts of her Cell biology study are interwoven with issues in Macrophage, Cytokine and Metabolism. Her biological study spans a wide range of topics, including Human disease, Computational biology, CRISPR and In vivo.
Her studies deal with areas such as Cancer and Tumor progression as well as Immune system. Her Cell research incorporates elements of Host and Effector. To a larger extent, Erika L. Pearce studies Biochemistry with the aim of understanding Cytotoxic T cell.
Erika L. Pearce mostly deals with Cell biology, Effector, Cell, Glycolysis and T cell. Her research in Cell biology intersects with topics in Experimental autoimmune encephalomyelitis, Immune system, Cytokine and PKM2. The Effector study combines topics in areas such as Cell therapy and Dysbiosis.
Her Glycolysis research is multidisciplinary, incorporating perspectives in Leukemia, Myeloid leukemia, Intracellular pH and Transplantation. Her T cell study combines topics in areas such as Transcriptome, Polyamine and FOXP3. Her studies deal with areas such as Tumor microenvironment, Function, Protein biosynthesis, Fatty acid-binding protein and Metabolism as well as Intracellular.
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Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
Chih Hao Chang;Jing Qiu;David O'Sullivan;Michael D. Buck.
Cell (2015)
Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens
Matthew M. Gubin;Xiuli Zhang;Heiko Schuster;Etienne Caron.
Nature (2014)
Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
Chih-Hao Chang;Jonathan D. Curtis;Leonard B. Maggi;Brandon Faubert.
Cell (2013)
Enhancing CD8 T-cell memory by modulating fatty acid metabolism.
Erika L. Pearce;Matthew C. Walsh;Pedro J. Cejas;Gretchen M. Harms.
Nature (2009)
Metabolic Pathways in Immune Cell Activation and Quiescence
Erika L. Pearce;Edward J. Pearce.
Immunity (2013)
Mitochondrial Respiratory Capacity Is a Critical Regulator of CD8+ T Cell Memory Development
Gerritje J.W. van der Windt;Bart Everts;Chih-Hao Chang;Jonathan D. Curtis.
Immunity (2012)
Control of Effector CD8+ T Cell Function by the Transcription Factor Eomesodermin
Erika L. Pearce;Alan C. Mullen;Gislâine A. Martins;Connie M. Krawczyk.
Science (2003)
Fueling immunity: insights into metabolism and lymphocyte function.
Erika L. Pearce;Maya C. Poffenberger;Chih-Hao Chang;Russell G. Jones.
Science (2013)
Mitochondrial Dynamics Controls T Cell Fate Through Metabolic Programming
Michael D D. Buck;Michael D D. Buck;David O'Sullivan;Ramon I I. Klein Geltink;Jonathan D D. Curtis.
Cell (2016)
T cell metabolism drives immunity
Michael D. Buck;David O’Sullivan;Erika L. Pearce.
Journal of Experimental Medicine (2015)
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