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Immunology

D-Index
79
Citations
30797
World Ranking
1661
National Ranking
821

Overview

Jonathan D. Powell is affiliated with the Johns Hopkins University School of Medicine in the United States. Their research focuses primarily on the intersection of immunology, molecular biology, and cancer, with additional emphasis on pulmonary and respiratory medicine.

Their recent publications include:

  • Metabolism of immune cells in cancer, 2020, Nature reviews. Cancer
  • Targeting glutamine metabolism enhances tumor-specific immunity by modulating suppressive myeloid cells, 2020, Journal of Clinical Investigation
  • Immune dysregulation as a driver of idiopathic pulmonary fibrosis, 2021, Journal of Clinical Investigation
  • An engineered IL-2 partial agonist promotes CD8+ T cell stemness, 2021, Nature
  • Metabolic programs define dysfunctional immune responses in severe COVID-19 patients, 2021, Cell Reports

Frequent co-authors with whom Jonathan D. Powell has collaborated include:

  • Chirag H. Patel
  • Elizabeth A. Thompson
  • Liang Zhao
  • Barbara S. Slusher
  • Robert D. Leone

Common publication venues for their work are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Immunology
  • Cancer Research
  • Regular and Young Investigator Award Abstracts
  • Journal of Clinical Investigation

Jonathan D. Powell has contributed extensively to several fields of study, with the largest focus areas being:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine
  • Immunology and Microbiology

Within these fields, their work concentrates on subfields such as:

  • Immunology
  • Molecular Biology
  • Oncology
  • Cancer Research
  • Pulmonary and Respiratory Medicine

The main research topics addressed by Jonathan D. Powell include:

  • Immune cells in cancer
  • Immune Cell Function and Interaction
  • Cancer, Hypoxia, and Metabolism
  • Epigenetics and DNA Methylation
  • CAR-T cell therapy research
  • T-cell and B-cell Immunology
  • PI3K/AKT/mTOR signaling in cancer

Best Publications

  • HLA-Haploidentical Bone Marrow Transplantation for Hematologic Malignancies Using Nonmyeloablative Conditioning and High-Dose, Posttransplantation Cyclophosphamide

    Leo Luznik;Paul V. O'Donnell;Paul V. O'Donnell;Heather J. Symons;Allen R. Chen

  • Stromal gene signatures in large-B-cell lymphomas

    G Lenz;G Wright;S S Dave;W Xiao

  • Role of LAG-3 in regulatory T cells.

    Ching Tai Huang;Creg J. Workman;Dallas Flies;Xiaoyu Pan

  • The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment.

    Greg M. Delgoffe;Thomas P. Kole;Yan Zheng;Paul E. Zarek

  • The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2

    Greg M Delgoffe;Kristen N Pollizzi;Adam T Waickman;Emily Heikamp

  • Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion

    Robert D. Leone;Liang Zhao;Judson M. Englert;Im Meng Sun

  • Regulation of Immune Responses by mTOR

    Jonathan D. Powell;Kristen N. Pollizzi;Emily B. Heikamp;Maureen R. Horton

  • Hyaluronan Fragments Act as an Endogenous Danger Signal by Engaging TLR2

    Kara A. Scheibner;Michael A. Lutz;Sada Boodoo;Matthew J. Fenton

  • Metabolism of immune cells in cancer

    Robert D. Leone;Jonathan D. Powell

  • A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells

    Paul E. Zarek;Ching Tai Huang;Eric R. Lutz;Jeanne Kowalski

  • Developing a pro-regenerative biomaterial scaffold microenvironment requires T helper 2 cells.

    Kaitlyn Sadtler;Kaitlyn Sadtler;Kenneth Estrellas;Kenneth Estrellas;Brian W. Allen;Brian W. Allen;Matthew T. Wolf;Matthew T. Wolf

  • The Mammalian Target of Rapamycin: Linking T Cell Differentiation, Function, and Metabolism

    Jonathan D. Powell;Greg M. Delgoffe

  • Egr-2 and Egr-3 are negative regulators of T cell activation.

    Meredith Safford;Samuel Collins;Michael A. Lutz;Amy Allen

  • Allogeneic Hematopoietic Stem-Cell Transplantation for Sickle Cell Disease

    Matthew M. Hsieh;Elizabeth M. Kang;Courtney D. Fitzhugh;M. Beth Link

  • High-dose cyclophosphamide as single-agent, short-course prophylaxis of graft-versus-host disease.

    Leo Luznik;Javier Bolaños-Meade;Marianna Zahurak;Allen R. Chen

  • mTOR, metabolism, and the regulation of T-cell differentiation and function

    Adam T. Waickman;Jonathan D. Powell

  • mTORC1 and mTORC2 selectively regulate CD8+ T cell differentiation

    Kristen N. Pollizzi;Chirag H. Patel;Im Hong Sun;Min Hee Oh

  • Integrating canonical and metabolic signalling programmes in the regulation of T cell responses.

    Kristen N. Pollizzi;Jonathan D. Powell

  • Targeting glutamine metabolism enhances tumor-specific immunity by modulating suppressive myeloid cells

    Min Hee Oh;Im Hong Sun;Liang Zhao;Robert D. Leone

  • Nonmyeloablative HLA-Matched Sibling Allogeneic Hematopoietic Stem Cell Transplantation for Severe Sickle Cell Phenotype

    Matthew M. Hsieh;Courtney D. Fitzhugh;R. Patrick Weitzel;Mary E. Link

  • Inhibition of Cell Cycle Progression by Rapamycin Induces T Cell Clonal Anergy Even in the Presence of Costimulation

    Jonathan D. Powell;Cara G. Lerner;Ronald H. Schwartz

Frequent Co-Authors

Barbara S. Slusher
Barbara S. Slusher Johns Hopkins University School of Medicine
Leo Luznik
Leo Luznik Johns Hopkins University
Francois Villinger
Francois Villinger University of Louisiana at Lafayette
Creg J. Workman
Creg J. Workman University of Pittsburgh
Dario A. A. Vignali
Dario A. A. Vignali University of Pittsburgh
Richard J. Jones
Richard J. Jones Johns Hopkins University
Ephraim J. Fuchs
Ephraim J. Fuchs Johns Hopkins University
Charles G. Drake
Charles G. Drake Columbia University
Drew M. Pardoll
Drew M. Pardoll Johns Hopkins University School of Medicine
Ronald H. Schwartz
Ronald H. Schwartz National Institutes of Health

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