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Biology and Biochemistry

D-Index
47
Citations
15026
World Ranking
18554
National Ranking
7579

Overview

Russell P. Rother is affiliated with Tetherex Pharmaceuticals in the United States and has conducted research primarily in the field of Medicine. Their work encompasses several subfields, including Pulmonary and Respiratory Medicine, Genetics, Pediatrics, Perinatology and Child Health, Hematology, and Physiology.

The scientist has contributed to research published in notable venues such as UNC Libraries and the European Respiratory Journal. Their recent papers include "Crizanlizumab for the Prevention of Pain Crises in Sickle Cell Disease" published in 2020 by UNC Libraries, and "Reduction in sputum inflammatory cells after a single dose of cepeprubart in COPD patients" published in 2025 by the European Respiratory Journal.

Russell P. Rother's research topics focus on various health and biomedical areas including:

  • Hemoglobinopathies and Related Disorders
  • Pharmacological Effects and Toxicity Studies
  • Iron Metabolism and Disorders
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Asthma and respiratory diseases
  • Respiratory and Cough-Related Research

The scientist has collaborated with several frequent co-authors, including:

  • Kenneth I. Ataga
  • Abdullah Kutlar
  • Julie Kanter
  • Darla Liles
  • Rodolfo Delfini Cançado

Best Publications

  • The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: a novel mechanism of human disease.

    Russell P. Rother;Leonard Bell;Peter Hillmen;Mark T. Gladwin

  • The complement inhibitor eculizumab in paroxysmal nocturnal hemoglobinuria.

    Peter Hillmen;Neal S. Young;Jörg Schubert;Robert A. Brodsky

  • Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria

    Russell P Rother;Scott A Rollins;Christopher F Mojcik;Robert A Brodsky

  • Effect of eculizumab on hemolysis and transfusion requirements in patients with paroxysmal nocturnal hemoglobinuria.

    Peter Hillmen;Claire Hall;Judith C W Marsh;Modupe Elebute

  • Crizanlizumab for the Prevention of Pain Crises in Sickle Cell Disease.

    Kenneth I. Ataga;Abdullah Kutlar;Julie Kanter;Darla Liles

  • Multicenter phase 3 study of the complement inhibitor eculizumab for the treatment of patients with paroxysmal nocturnal hemoglobinuria.

    Robert A. Brodsky;Neal S. Young;Elisabetta Antonioli;Antonio M. Risitano

  • Effect of the complement inhibitor eculizumab on thromboembolism in patients with paroxysmal nocturnal hemoglobinuria.

    Peter Hillmen;Petra Muus;Ulrich Dührsen;Antonio M. Risitano

  • Inhibition of complement activity by humanized anti-C5 antibody and single-chain Fv

    Thomas C. Thomas;Scott A. Rollins;Russell P. Rother;Michelle A. Giannoni

  • Eculizumab for congenital atypical hemolytic-uremic syndrome.

    Ralph A Gruppo;Russell P Rother

  • Effective induction of naive and recall T-cell responses by targeting antigen to human dendritic cells via a humanized anti–DC-SIGN antibody

    Paul J. Tacken;Paul J. Tacken;I. Jolanda M. de Vries;I. Jolanda M. de Vries;Karlijn Gijzen;Karlijn Gijzen;Ben Joosten;Ben Joosten

  • Mannose-Binding Lectin Is a Regulator of Inflammation That Accompanies Myocardial Ischemia and Reperfusion Injury

    Mary C. Walsh;Todd Bourcier;Kazue Takahashi;Lei Shi

  • Composition and method for treating glomerulonephritis and other inflammatory diseases

    Mark J Evans;Louis Matis;Eileen Elliott Mueller;Steven H Nye

  • Sustained response and long-term safety of eculizumab in paroxysmal nocturnal hemoglobinuria.

    Anita Hill;Peter Hillmen;Peter Hillmen;Stephen J. Richards;Stephen J. Richards;Dupe Elebute;Dupe Elebute

  • Eculizumab prevents anti-ganglioside antibody-mediated neuropathy in a murine model.

    Susan K. Halstead;Femke M. P. Zitman;Peter D. Humphreys;Kay Greenshields

  • A novel mechanism of retrovirus inactivation in human serum mediated by anti-alpha-galactosyl natural antibody.

    R P Rother;W L Fodor;J P Springhorn;C W Birks

  • Gastrointestinal ischemia-reperfusion injury is lectin complement pathway dependent without involving C1q.

    Melanie L. Hart;Kathleen A. Ceonzo;Lisa A. Shaffer;Kazue Takahashi

  • Long-term effect of the complement inhibitor eculizumab on kidney function in patients with paroxysmal nocturnal hemoglobinuria

    Peter Hillmen;Modupe Elebute;Richard Kelly;Alvaro Urbano-Ispizua

  • Eculizumab prevents intravascular hemolysis in patients with paroxysmal nocturnal hemoglobinuria and unmasks low-level extravascular hemolysis occurring through C3 opsonization

    Anita Hill;Russell P Rother;Louise Arnold;Richard Kelly

  • Effect of eculizumab on haemolysis-associated nitric oxide depletion, dyspnoea, and measures of pulmonary hypertension in patients with paroxysmal nocturnal haemoglobinuria

    Anita Hill;Russell P. Rother;Xunde Wang;Sidney M. Morris

  • The management of pregnancy in paroxysmal nocturnal haemoglobinuria on long term eculizumab.

    Richard Kelly;Louise Arnold;Stephen Richards;Anita Hill

Frequent Co-Authors

Louis A. Matis
Louis A. Matis Alexion Pharma (Switzerland)
Peter Hillmen
Peter Hillmen St James's University Hospital
Neal S. Young
Neal S. Young National Institutes of Health
Gérard Socié
Gérard Socié Université Paris Cité
Monica Bessler
Monica Bessler Children's Hospital of Philadelphia
Jeff Szer
Jeff Szer Peter MacCallum Cancer Centre
Hubert Schrezenmeier
Hubert Schrezenmeier University of Ulm
Lucio Luzzatto
Lucio Luzzatto University of Florence
Ulrich Dührsen
Ulrich Dührsen University of Duisburg-Essen
Gregory L. Stahl
Gregory L. Stahl Brigham and Women's Hospital

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