World's Best Scientists 2026 revealed!
Patrick Mehlen

Patrick Mehlen

D-Index & Metrics

Biology and Biochemistry

D-Index
79
Citations
33349
World Ranking
4215
National Ranking
107

Patrick Mehlen publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Patrick Mehlen sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 231 publications — 61st percentile

61% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Patrick Mehlen D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Patrick Mehlen sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 79 D-Index — 79th percentile

79% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Patrick Mehlen is affiliated with the UniCancer Group in France. Their research spans several interconnected fields including Medicine, Biochemistry, Genetics and Molecular Biology, and Neuroscience. Within these broad fields, their work delves into Molecular Biology, Cellular and Molecular Neuroscience, Oncology, Developmental Neuroscience, and Epidemiology.

The main topics addressed by Mehlen's research concern Axon Guidance and Neuronal Signaling, Angiogenesis and VEGF in Cancer, Hedgehog Signaling Pathway Studies, Neurogenesis and Neuroplasticity Mechanisms, Developmental Biology and Gene Regulation, Cancer Cells and Metastasis, and HER2/EGFR in Cancer Research.

Mehlen has contributed substantially to the scientific literature, publishing in notable venues. These include:

  • Nature Communications (5 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (4 publications)
  • EMBO Molecular Medicine (3 publications)
  • Nature (2 publications)
  • Cell Death and Differentiation (2 publications)

Some of their recent papers, with publication year and venue, are:

  • "Netrin-1 blockade inhibits tumour growth and EMT features in endometrial cancer," 2023, Nature
  • "Pharmacological targeting of netrin-1 inhibits EMT in cancer," 2023, Nature
  • "Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1," 2021, Nature Communications
  • "Netrin-1 and its receptor DCC modulate survival and death of dopamine neurons and Parkinson's disease features," 2020, The EMBO Journal
  • "Dependence receptors: new targets for cancer therapy," 2021, EMBO Molecular Medicine

Patrick Mehlen has collaborated frequently with several researchers, notably:

  • Nicolas Rama (13 collaborations)
  • Benjamin Gibert (12 collaborations)
  • Benjamin Ducarouge (11 collaborations)
  • Nicolas Gadot (8 collaborations)
  • David Neves (6 collaborations)

Among awards, Patrick Mehlen is recognized as a member of the European Molecular Biology Organization (EMBO).

Best Publications

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

    Galluzzi L;Vitale I;Vitale I;Vitale I;Abrams Jm;Alnemri Es

  • Metastasis: a question of life or death

    Patrick Mehlen;Alain Puisieux

  • Cell death in the nervous system

    Dale E. Bredesen;Rammohan V. Rao;Patrick Mehlen;Patrick Mehlen

  • Human hsp27, Drosophila hsp27 and human alphaB-crystallin expression-mediated increase in glutathione is essential for the protective activity of these proteins against TNFalpha-induced cell death

    P Mehlen;C Kretz-Remy;X Préville;A P Arrigo

  • Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

    L. Galluzzi;L. Galluzzi;L. Galluzzi;S. A. Aaronson;J. Abrams;E. S. Alnemri

  • Small Stress Proteins as Novel Regulators of Apoptosis HEAT SHOCK PROTEIN 27 BLOCKs FAS/APO-1- AND STAUROSPORINE-INDUCED CELL DEATH

    Patrick Mehlen;Klaus Schulze-Osthoff;André-Patrick Arrigo

  • The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis

    Patrick Mehlen;Shahrooz Rabizadeh;Shahrooz Rabizadeh;Scott J. Snipas;Scott J. Snipas;Nuria Assa-Munt;Nuria Assa-Munt

  • Notch Signaling in the Tumor Microenvironment.

    Olivier Meurette;Patrick Mehlen

  • Constitutive expression of human hsp27, Drosophila hsp27, or human alpha B-crystallin confers resistance to TNF- and oxidative stress-induced cytotoxicity in stably transfected murine L929 fibroblasts.

    P Mehlen;X Preville;P Chareyron;J Briolay

  • Netrin-1 acts as a survival factor via its receptors UNC5H and DCC.

    Fabien Llambi;Frédéric Causeret;Evelyne Bloch‐Gallego;Patrick Mehlen

  • Inhibition of Neuroepithelial Patched-Induced Apoptosis by Sonic Hedgehog

    Chantal Thibert;Marie-Aimée Teillet;Françoise Lapointe;Laetitia Mazelin

  • Netrin-1 controls colorectal tumorigenesis by regulating apoptosis.

    Laetitia Mazelin;Agnès Bernet;Christelle Bonod-Bidaud;Laurent Pays

  • Inhibition of I kappa B-alpha phosphorylation and degradation and subsequent NF-kappa B activation by glutathione peroxidase overexpression.

    C Kretz-Remy;P Mehlen;M E Mirault;A P Arrigo

  • Netrin-1-mediated axon outgrowth requires deleted in colorectal cancer-dependent MAPK activation

    Christelle Forcet;Elke Stein;Laurent Pays;Véronique Corset

  • HSP27 as a Mediator of Confluence-dependent Resistance to Cell Death Induced by Anticancer Drugs

    Carmen Garrido;Patrick Ottavi;Annie Fromentin;Arlette Hammann

  • The RET proto‐oncogene induces apoptosis: a novel mechanism for Hirschsprung disease

    Marie‐Claire Bordeaux;Christelle Forcet;Laure Granger;Véronique Corset

  • RGM and its receptor neogenin regulate neuronal survival

    Eiji Matsunaga;Servane Tauszig-Delamasure;Philippe P. Monnier;Bernhard K. Mueller

  • hsp27 as a Switch between Differentiation and Apoptosis in Murine Embryonic Stem Cells

    Patrick Mehlen;Anne Mehlen;Jacqueline Godet;André-Patrick Arrigo

  • Large unphosphorylated aggregates as the active form of hsp27 which controls intracellular reactive oxygen species and glutathione levels and generates a protection against TNFalpha in NIH-3T3-ras cells.

    Patrick Mehlen;Eilen Hickey;Lee A. Weber;André-Patrick Arrigo

Frequent Co-Authors

André-Patrick Arrigo
André-Patrick Arrigo Claude Bernard University Lyon 1
Dale E. Bredesen
Dale E. Bredesen University of California, Los Angeles
Alain Chédotal
Alain Chédotal Institut de la Vision
Oliver Kepp
Oliver Kepp Institut Gustave Roussy
Lorenzo Galluzzi
Lorenzo Galluzzi Cornell University
Carmen Garrido
Carmen Garrido University of Burgundy
Ilio Vitale
Ilio Vitale University of Rome Tor Vergata
Jean-Yves Scoazec
Jean-Yves Scoazec Grenoble Alpes University
Sharad Kumar
Sharad Kumar University of Adelaide
Simone Fulda
Simone Fulda Goethe University Frankfurt

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