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Biology and Biochemistry

D-Index
56
Citations
12212
World Ranking
14361
National Ranking
6049

Overview

Bernard E. Weissman is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a substantial body of work in medicine. The main subfields of their study include molecular biology, pathology and forensic medicine, cancer research, oncology, and obstetrics and gynecology.

The scientist's research addresses various topics related to cancer and molecular mechanisms. The main topics covered in their publications are:

  • Chromatin Remodeling and Cancer
  • Cancer Mechanisms and Therapy
  • Mechanisms of cancer metastasis
  • RNA modifications and cancer
  • Genomics, phytochemicals, and oxidative stress
  • Protein Degradation and Inhibitors
  • Epigenetics and DNA Methylation

Bernard E. Weissman has contributed to numerous scientific papers. Some recent publications include:

  • Small-Cell Carcinoma of the Ovary, Hypercalcemic Type-Genetics, New Treatment Targets, and Current Management Guidelines (2020, Clinical Cancer Research)
  • The novel reversible LSD1 inhibitor SP-2577 promotes anti-tumor immunity in SWItch/Sucrose-NonFermentable (SWI/SNF) complex mutated ovarian cancer (2020, PLoS ONE)
  • Re-expression of SMARCA4/BRG1 in small cell carcinoma of ovary, hypercalcemic type (SCCOHT) promotes an epithelial-like gene signature through an AP-1-dependent mechanism (2020, eLife)
  • Re-assigning the histologic identities of COV434 and TOV-112D ovarian cancer cell lines (2020, Gynecologic Oncology)
  • Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non-Small Cell Lung Carcinoma (2020, Molecular Cancer Research)

The publication venues in which Bernard E. Weissman frequently publishes include:

  • UNC Libraries
  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Clinical Cancer Research
  • PLoS ONE

Collaborative research is a significant part of their work. Frequent co-authors include:

  • Michael B. Major
  • Jeffrey M. Trent
  • William P.D. Hendricks
  • David G. Huntsman
  • Yemin Wang

Best Publications

  • KiSS-1, a Novel Human Malignant Melanoma Metastasis-Suppressor Gene

    Jeong Hyung Lee;Mary E. Miele;Deana J. Hicks;Karen K. Phillips

  • Introduction of a normal human chromosome 11 into a Wilms' tumor cell line controls its tumorigenic expression.

    Bernard E. Weissman;Paul J. Saxon;Steve R. Pasquale;Gary R. Jones

  • Selective inhibition of growth-related gene expression in murine keratinocytes by transforming growth factor beta.

    R J Coffey;C C Bascom;N J Sipes;R Graves-Deal

  • Human cell hybrids: analysis of transformation and tumorigenicity

    Eric J. Stanbridge;Channing J Der;Claus Jens Doersen;Robyn Y. Nishimi

  • Loss of BRG1/BRM in Human Lung Cancer Cell Lines and Primary Lung Cancers: Correlation with Poor Prognosis

    David N. Reisman;Janiece Sciarrotta;Weidong Wang;William K. Funkhouser

  • BRG-1 is required for RB-mediated cell cycle arrest

    Matthew W. Strobeck;Karen E. Knudsen;Anne F. Fribourg;Marc F. DeCristofaro

  • Growth Modulation of Mouse Keratinocytes by Transforming Growth Factors

    Robert J. Coffey;Nancy J. Sipes;Charles C. Bascom;Ramona Graves-Deal

  • WT1 modulates apoptosis by transcriptionally upregulating the bcl-2 proto-oncogene.

    Marty W. Mayo;Cun Yu Wang;S. Scott Drouin;Lee V. Madrid

  • BALB and Kirsten murine sarcoma viruses alter growth and differentiation of EGF-dependent balb/c mouse epidermal keratinocyte lines.

    Bernard E. Weissman;Stuart A. Aaronson

  • Re-expression of hSNF5/INI1/BAF47 in pediatric tumor cells leads to G1 arrest associated with induction of p16ink4a and activation of RB.

    Bryan L. Betz;Matthew W. Strobeck;David N. Reisman;Erik S. Knudsen

  • Chromosome localization and genomic structure of the KiSS-1 metastasis suppressor gene (KISS1)

    Ande West;Patrick J. Vojta;Danny R. Welch;Bernard E. Weissman

  • Characterization of SWI/SNF protein expression in human breast cancer cell lines and other malignancies

    Marc F. D Cristofaro;Bryan L. Betz;Checo J. Rorie;David N. Reisman

  • The melanoma differentiation-associated gene mda-6, which encodes the cyclin-dependent kinase inhibitor p21, is differentially expressed during growth, differentiation and progression in human melanoma cells.

    Hongping Jiang;Jian Lin;Zao-Zhong Su;M. Herlyn

  • The role of INI1 and the SWI/SNF complex in the development of rhabdoid tumors: Meeting summary from the workshop on childhood atypical teratoid/rhabdoid tumors

    Jaclyn A. Biegel;Ganjarn Kalpana;Erik S. Knudsen;Roger J. Packer

  • Analysis of the expression of cell cycle regulators in Ewing cell lines : EWS-FLI-1 modulates p57KIP2 and c-Myc expression

    Luce Dauphinot;Catherine De Oliveira;Thomas Melot;Nicolas Sevenet

  • SWI/SNF chromatin remodeling complexes and cancer

    Jaclyn A. Biegel;Tracy M. Busse;Tracy M. Busse;Bernard E. Weissman

  • Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type

    Anthony N. Karnezis;Yemin Wang;Pilar Ramos;William P.D. Hendricks

  • Microcell-mediated transfer of chromosome 6 into metastatic human C8161 melanoma cells suppresses metastasis but does not inhibit tumorigenicity

    Danny R. Welch;Pengchin Chen;Mary E. Miele;Carl T. McGary

  • Concomitant down-regulation of BRM and BRG1 in human tumor cell lines: differential effects on RB-mediated growth arrest vs CD44 expression.

    David N. Reisman;Matthew W. Strobeck;Bryan L. Betz;Janiece Sciariotta

  • BAF57 governs androgen receptor action and androgen-dependent proliferation through SWI/SNF.

    Kevin A. Link;Craig J. Burd;Erin Williams;Thomas Marshall

Frequent Co-Authors

Jeffrey M. Trent
Jeffrey M. Trent Translational Genomics Research Institute
David G. Huntsman
David G. Huntsman University of British Columbia
Eric J. Stanbridge
Eric J. Stanbridge University of California, Irvine
Gregg B. Morin
Gregg B. Morin University of British Columbia
Danny R. Welch
Danny R. Welch University of Kansas
Charles W. M. Roberts
Charles W. M. Roberts St. Jude Children's Research Hospital
Larry S. Sherman
Larry S. Sherman Oregon National Primate Research Center
Karen E. Knudsen
Karen E. Knudsen Thomas Jefferson University
Christopher D.M. Fletcher
Christopher D.M. Fletcher Brigham and Women's Hospital
Norma J. Nowak
Norma J. Nowak University at Buffalo, State University of New York

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