D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 85 Citations 24,262 184 World Ranking 528 National Ranking 313
Medicine D-index 90 Citations 27,438 220 World Ranking 5984 National Ranking 3308

Research.com Recognitions

Awards & Achievements

2015 - Presidential Award, Clinical Immunology Society

2009 - Distinguished Service Award, Clinical Immunology Society

Overview

What is he best known for?

The fields of study he is best known for:

  • Immune system
  • Internal medicine
  • Gene

His scientific interests lie mostly in Immunology, Internal medicine, Immune system, Cytokine and T cell. His research on Immunology often connects related areas such as Chemotherapy. His research integrates issues of Endocrinology and Oncology in his study of Internal medicine.

In his work, Gene expression, Transgene, Gene, Viral vector and Donor Lymphocytes is strongly intertwined with Antibody, which is a subfield of Immune system. His research in the fields of Interferon gamma and Janus kinase overlaps with other disciplines such as STAT protein. Thomas A. Fleisher interconnects Molecular biology, Autoimmune lymphoproliferative syndrome and CD5 in the investigation of issues within T cell.

His most cited work include:

  • T Lymphocyte-Directed Gene Therapy for ADA− SCID: Initial Trial Results After 4 Years (1193 citations)
  • Age, thymopoiesis, and CD4+ t-lymphocyte regeneration after intensive chemotherapy (957 citations)
  • Activated STING in a Vascular and Pulmonary Syndrome (625 citations)

What are the main themes of his work throughout his whole career to date?

Thomas A. Fleisher mainly investigates Immunology, Internal medicine, Immune system, Molecular biology and Autoimmune lymphoproliferative syndrome. His research in CD8, T cell, Lymphocyte, Autoimmunity and Antibody are components of Immunology. The Internal medicine study combines topics in areas such as Gastroenterology, Endocrinology, Surgery and Oncology.

His Immune system research is multidisciplinary, relying on both Severe combined immunodeficiency and Cytokine. His work deals with themes such as Mutation and Antigen, which intersect with Molecular biology. His Autoimmune lymphoproliferative syndrome study integrates concerns from other disciplines, such as Fas ligand, Autoimmune disease and Lymphoma.

He most often published in these fields:

  • Immunology (55.52%)
  • Internal medicine (21.72%)
  • Immune system (13.79%)

What were the highlights of his more recent work (between 2011-2021)?

  • Immunology (55.52%)
  • Internal medicine (21.72%)
  • Severe combined immunodeficiency (7.24%)

In recent papers he was focusing on the following fields of study:

Thomas A. Fleisher mainly investigates Immunology, Internal medicine, Severe combined immunodeficiency, Primary immunodeficiency and Hematopoietic stem cell transplantation. His research on Immunology often connects related topics like Autoimmune lymphoproliferative syndrome. His Internal medicine research is multidisciplinary, incorporating elements of Gastroenterology, Endocrinology, Surgery and Oncology.

His research investigates the connection with Gastroenterology and areas like Neutropenia which intersect with concerns in Cancer and Cytokine. The study incorporates disciplines such as Retrospective cohort study, Pediatrics, Newborn screening and Lymphocyte proliferation in addition to Severe combined immunodeficiency. His work in Immune dysregulation tackles topics such as Germline mutation which are related to areas like Pathology.

Between 2011 and 2021, his most popular works were:

  • Activated STING in a Vascular and Pulmonary Syndrome (625 citations)
  • Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4 (485 citations)
  • An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome (394 citations)

In his most recent research, the most cited papers focused on:

  • Immune system
  • Internal medicine
  • Gene

His primary areas of study are Immunology, Hematopoietic stem cell transplantation, Severe combined immunodeficiency, Transplantation and Internal medicine. Thomas A. Fleisher has included themes like Cancer research and Neutropenia in his Immunology study. His Hematopoietic stem cell transplantation research incorporates elements of Infectious disease, Bacterial vaccine, Intensive care medicine, Transmission and Viral Vaccine.

Thomas A. Fleisher has researched Severe combined immunodeficiency in several fields, including Primary immunodeficiency, Surgery and Newborn screening. The various areas that Thomas A. Fleisher examines in his Transplantation study include Adoptive cell transfer, Stem cell and Interleukin 21, Lymphokine-activated killer cell. His Internal medicine study combines topics from a wide range of disciplines, such as Leukapheresis and Oncology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

T Lymphocyte-Directed Gene Therapy for ADA− SCID: Initial Trial Results After 4 Years

R. Michael Blaese;Kenneth W. Culver;A. Dusty Miller;Charles S. Carter.
Science (1995)

1797 Citations

Age, thymopoiesis, and CD4+ t-lymphocyte regeneration after intensive chemotherapy

Crystal L. Mackall;Thomas A. Fleisher;Margaret R. Brown;Mary P. Andrich.
The New England Journal of Medicine (1995)

1209 Citations

Activated STING in a Vascular and Pulmonary Syndrome

Y. Liu;A.A. Jesus;B. Marrero;D. Yang.
The New England Journal of Medicine (2014)

739 Citations

Tocilizumab in systemic lupus erythematosus: data on safety, preliminary efficacy, and impact on circulating plasma cells from an open-label phase I dosage-escalation study

Gabor G. Illei;Yuko Shirota;Cheryl H. Yarboro;Jimmy Daruwalla.
Arthritis & Rheumatism (2010)

599 Citations

Flow cytometric analysis of the granulocyte respiratory burst: a comparison study of fluorescent probes.

S.J. Vowells;S. Sekhsaria;H.L. Malech;M. Shalit.
Journal of Immunological Methods (1995)

572 Citations

Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4

Hye Sun Kuehn;Weiming Ouyang;Bernice Lo;Elissa K. Deenick;Elissa K. Deenick.
Science (2014)

548 Citations

Redistribution, Hyperproliferation, Activation of Natural Killer Cells and CD8 T Cells, and Cytokine Production During First-in-Human Clinical Trial of Recombinant Human Interleukin-15 in Patients With Cancer

Kevin C. Conlon;Enrico Lugli;Hugh C. Welles;Hugh C. Welles;Steven A. Rosenberg.
Journal of Clinical Oncology (2015)

529 Citations

Transplantation Outcomes for Severe Combined Immunodeficiency, 2000–2009

Sung Yun Pai;Brent R. Logan;Linda M. Griffith;Rebecca H. Buckley.
The New England Journal of Medicine (2014)

519 Citations

Early-Onset Stroke and Vasculopathy Associated with Mutations in ADA2

Qing Zhou;Dan Yang;Amanda K Ombrello;Andrey V Zavialov.
The New England Journal of Medicine (2014)

508 Citations

Clinical, Immunologic, and Genetic Features of an Autoimmune Lymphoproliferative Syndrome Associated With Abnormal Lymphocyte Apoptosis

Michael C. Sneller;Jin Wang;Janet K. Dale;Warren Strober.
Blood (1997)

496 Citations

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