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Immunology

D-Index
53
Citations
10045
World Ranking
3982
National Ranking
1820

Overview

Jack J. Bleesing is affiliated with Cincinnati Children's Hospital Medical Center in the United States. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with significant contributions to Immunology, Hematology, Genetics, Epidemiology, and Oncology subfields.

Their main research topics include:

  • Immunodeficiency and Autoimmune Disorders
  • Blood disorders and treatments
  • Immune Cell Function and Interaction
  • Hematopoietic Stem Cell Transplantation
  • Complement system in diseases
  • Autoimmune and Inflammatory Disorders Research
  • Renal Transplantation Outcomes and Treatments

Jack J. Bleesing has authored numerous papers, with recent publications including:

  • Complement blockade for TA-TMA: lessons learned from large pediatric cohort treated with eculizumab, 2020, Blood
  • Excellent outcomes following hematopoietic cell transplantation for Wiskott-Aldrich syndrome: a PIDTC report, 2020, Blood
  • Immunodeficiency and bone marrow failure with mosaic and germline TLR8 gain of function, 2020, Blood
  • Measuring the effect of newborn screening on survival after haematopoietic cell transplantation for severe combined immunodeficiency: a 36-year longitudinal study from the Primary Immune Deficiency Treatment Consortium, 2023, The Lancet
  • Thinking Beyond HLH: Clinical Features of Patients with Concurrent Presentation of Hemophagocytic Lymphohistiocytosis and Thrombotic Microangiopathy, 2020, Journal of Clinical Immunology

The frequent venues where Bleesing's work is published are:

  • Blood
  • Journal of Clinical Immunology
  • Transplantation and Cellular Therapy
  • Biology of Blood and Marrow Transplantation
  • Journal of Allergy and Clinical Immunology

Among frequent collaborators are:

  • Rebecca Marsh
  • Stella M. Davies
  • Luigi D. Notarangelo
  • Sharat Chandra
  • Michael B. Jordan

Best Publications

  • Patients with LRBA deficiency show CTLA4 loss and immune dysregulation responsive to abatacept therapy

    Bernice Lo;Kejian Zhang;Wei Lu;Lixin Zheng

  • Revised diagnostic criteria and classification for the autoimmune lymphoproliferative syndrome (ALPS): report from the 2009 NIH International Workshop.

    Joao B. Oliveira;Jack J. Bleesing;Umberto Dianzani;Thomas A. Fleisher

  • A Modified γ-Retrovirus Vector for X-Linked Severe Combined Immunodeficiency

    Salima Hacein-Bey-Abina;Sung Yun Pai;H. Bobby Gaspar;Myriam Armant

  • Diagnostic and risk criteria for HSCT-associated thrombotic microangiopathy: a study in children and young adults.

    Sonata Jodele;Stella M. Davies;Adam Lane;Jane Khoury

  • Mg2+ Regulates Cytotoxic Functions of NK and CD8 T Cells in Chronic EBV Infection Through NKG2D

    Benjamin Chaigne-Delalande;Feng-Yen Li;Feng-Yen Li;Geraldine M. O’Connor;Marshall J. Lukacs

  • Salvage Therapy of Refractory Hemophagocytic Lymphohistiocytosis with Alemtuzumab

    Rebecca A. Marsh;Carl E. Allen;Kenneth L. McClain;Joanna L. Weinstein

  • Reduced-intensity conditioning significantly improves survival of patients with hemophagocytic lymphohistiocytosis undergoing allogeneic hematopoietic cell transplantation

    Rebecca A. Marsh;Gretchen Vaughn;Mi-Ok Kim;Dandan Li

  • XIAP deficiency: a unique primary immunodeficiency best classified as X-linked familial hemophagocytic lymphohistiocytosis and not as X-linked lymphoproliferative disease

    Rebecca A. Marsh;Lisa Madden;Brenda J. Kitchen;Rajen Mody

  • Long-term follow-up of IPEX syndrome patients after different therapeutic strategies: An international multicenter retrospective study

    Federica Barzaghi;Laura Cristina Amaya Hernandez;Benedicte Neven;Silvia Ricci

  • Sirolimus is effective in relapsed/refractory autoimmune cytopenias: results of a prospective multi-institutional trial

    Karen L. Bride;Karen L. Bride;Tiffaney Vincent;Tiffaney Vincent;Kim Smith-Whitley;Kim Smith-Whitley;Michele P. Lambert;Michele P. Lambert

  • Complement blockade for TA-TMA: lessons learned from a large pediatric cohort treated with eculizumab

    Sonata Jodele;Sonata Jodele;Christopher E Dandoy;Christopher E Dandoy;Adam Lane;Adam Lane;Benjamin L Laskin

  • Treatment with sirolimus results in complete responses in patients with autoimmune lymphoproliferative syndrome

    David T. Teachey;Robert Greiner;Alix Seif;Edward Attiyeh

  • Broad-spectrum antibodies against self-antigens and cytokines in RAG deficiency

    Jolan E. Walter;Lindsey B. Rosen;Krisztian Csomos;Jacob M. Rosenberg

  • Restimulation-induced apoptosis of T cells is impaired in patients with X-linked lymphoproliferative disease caused by SAP deficiency

    Andrew L. Snow;Rebecca A. Marsh;Scott M. Krummey;Philip Roehrs

  • Immunophenotypic profiles in families with autoimmune lymphoproliferative syndrome

    Jack J. H. Bleesing;Margaret R. Brown;Stephen E. Straus;Janet K. Dale

  • SCID genotype and 6-month posttransplant CD4 count predict survival and immune recovery

    Elie Haddad;Brent R. Logan;Linda M. Griffith;Rebecca H. Buckley

  • Autoimmune lymphoproliferative syndrome. A human disorder of abnormal lymphocyte survival.

    Jack J.H. Bleesing;Stephen E. Straus;Thomas A. Fleisher

  • Use of intravenous immunoglobulin and adjunctive therapies in the treatment of primary immunodeficiencies: A working group report of and study by the Primary Immunodeficiency Committee of the American Academy of Allergy Asthma and Immunology.

    Pierre L. Yong;John Boyle;Mark Ballow;Marcia Boyle

  • Perforin and CD107a testing is superior to NK cell function testing for screening patients for genetic HLH.

    Tamar S. Rubin;Kejian Zhang;Carrie Gifford;Adam Lane

  • Allogeneic hematopoietic cell transplantation for XIAP deficiency: an international survey reveals poor outcomes

    Rebecca A. Marsh;Kanchan Rao;Prakash Satwani;Kai Lehmberg

  • Introduction to flow cytometry.

    Gerald E Marti;Maryalice Stetler-Stevenson;Jack J.H Bleesing;Thomas A Fleisher

Frequent Co-Authors

Stella M. Davies
Stella M. Davies Cincinnati Children's Hospital Medical Center
Alexandra H. Filipovich
Alexandra H. Filipovich Cincinnati Children's Hospital Medical Center
Michael B. Jordan
Michael B. Jordan Cincinnati Children's Hospital Medical Center
Thomas A. Fleisher
Thomas A. Fleisher National Institutes of Health
Jennifer M. Puck
Jennifer M. Puck University of California, San Francisco
Jolan E. Walter
Jolan E. Walter University of South Florida
Morton J. Cowan
Morton J. Cowan University of California, San Francisco
Andrew R. Gennery
Andrew R. Gennery Newcastle University
Sung-Yun Pai
Sung-Yun Pai National Institutes of Health
Sharon E. Straus
Sharon E. Straus University of Toronto

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