Edward W. Tate

Overview

Best Publications

• FSP1 is a glutathione-independent ferroptosis suppressor

  Sebastian Doll;Florencio Porto Freitas;Ron Shah;Maceler Aldrovandi

  2962
  Citations

• Protein myristoylation in health and disease

  Megan H. Wright;William P. Heal;David J. Mann;Edward W. Tate

  288
  Citations

• Global profiling of co- and post-translationally N -myristoylated proteomes in human cells

  Emmanuelle Thinon;Remigiusz A. Serwa;Malgorzata Broncel;James A. Brannigan

  262
  Citations

• Validation of N -myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach

  Megan H. Wright;Barbara Clough;Mark D. Rackham;Kaveri Rangachari

  235
  Citations

• Activity-based probes: discovering new biology and new drug targets

  William P. Heal;T. H. Tam Dang;Edward W. Tate

  226
  Citations

• Antibody–PROTAC Conjugates Enable HER2-Dependent Targeted Protein Degradation of BRD4

  Marı A Maneiro;Nafsika Forte;Maria M Shchepinova;Cyrille S Kounde

  215
  Citations

• Chemical and biomimetic total syntheses of natural and engineered MCoTI cyclotides

  Panumart Thongyoo;Núria Roqué-Rosell;Robin J. Leatherbarrow;Edward W. Tate

  177
  Citations

• N-Myristoyl transferase-mediated protein labelling in vivo.

  William P. Heal;Sasala R. Wickramasinghe;Robin J. Leatherbarrow;Edward W. Tate

  165
  Citations

• Potent Inhibitors of β-Tryptase and Human Leukocyte Elastase Based on the MCoTI-II Scaffold

  Panumart Thongyoo;Camille Bonomelli;Robin J. Leatherbarrow;Edward W. Tate

  153
  Citations

• Genome-wide Functional Analysis of Plasmodium Protein Phosphatases Reveals Key Regulators of Parasite Development and Differentiation

  David S. Guttery;Benoit Poulin;Abhinay Ramaprasad;Richard J. Wall

  137
  Citations

• Dynamic Protein Acylation: New Substrates, Mechanisms, and Drug Targets.

  Thomas Lanyon-Hogg;Monica Faronato;Remigiusz A. Serwa;Edward W. Tate

  134
  Citations

• Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus.

  Aurélie Mousnier;Aurélie Mousnier;Andrew S. Bell;Dawid P. Swieboda;Julia Morales-Sanfrutos

  127
  Citations

• N-Myristoyltransferase from Leishmania Donovani: Structural and Functional Characterisation of a Potential Drug Target for Visceral Leishmaniasis.

  James A. Brannigan;Barbara A. Smith;Zhiyong Yu;Andrzej M. Brzozowski

  125
  Citations

• Multifunctional protein labeling via enzymatic N-terminal tagging and elaboration by click chemistry

  William P Heal;Megan H Wright;Emmanuelle Thinon;Edward W Tate

  120
  Citations

• Global profiling of protein lipidation using chemical proteomic technologies.

  Edward W Tate;Karunakaran A Kalesh;Thomas Lanyon-Hogg;Elisabeth M Storck

  113
  Citations

• Selective inhibitors of protozoan protein N-myristoyltransferases as starting points for tropical disease medicinal chemistry programs.

  Andrew S. Bell;James E. Mills;Gareth P. Williams;James A. Brannigan

  111
  Citations

• Multifunctional Reagents for Quantitative Proteome-Wide Analysis of Protein Modification in Human Cells and Dynamic Profiling of Protein Lipidation During Vertebrate Development

  Malgorzata Broncel;Remigiusz A. Serwa;Paulina Ciepla;Eberhard Krause

  103
  Citations

• Bioorthogonal chemical tagging of protein cholesterylation in living cells

  William P. Heal;Biljana Jovanovic;Sara Bessin;Megan H. Wright

  101
  Citations

• Dual chemical probes enable quantitative system-wide analysis of protein prenylation and prenylation dynamics.

  Elisabeth M. Storck;Elisabeth M. Storck;Julia Morales-Sanfrutos;Remigiusz A. Serwa;Remigiusz A. Serwa;Nattawadee Panyain

  98
  Citations

• A caged E3 ligase ligand for PROTAC-mediated protein degradation with light

  Cyrille S Kounde;Maria M Shchepinova;Charlie N Saunders;Marcel Muelbaier

  96
  Citations