World's Best Scientists 2026 revealed!
Barbara Papadopoulou

Barbara Papadopoulou

D-Index & Metrics

Microbiology

D-Index
64
Citations
11570
World Ranking
2655
National Ranking
72

Genetics

D-Index
65
Citations
11812
World Ranking
2721
National Ranking
94

Overview

Barbara Papadopoulou is affiliated with Université Laval in Canada and focuses on research areas within biochemistry, genetics, and molecular biology, as well as medicine. Their work spans several subfields including molecular biology, public health, environmental and occupational health, epidemiology, cardiology and cardiovascular medicine, and parasitology.

Their research prominently covers topics such as:

  • Research on Leishmaniasis Studies
  • RNA and protein synthesis mechanisms
  • RNA Research and Splicing
  • Trypanosoma species research and implications
  • Viral Infections and Immunology Research
  • Parasites and Host Interactions
  • Helminth infection and control

Barbara Papadopoulou has published papers in various scientific venues, including:

  • Scientific Reports
  • PLoS neglected tropical diseases
  • Nucleic Acids Research
  • Microbial Cell
  • Methods in molecular biology

Recent papers authored or co-authored by Papadopoulou include:

  • Identification of novel proteins and mRNAs differentially bound to the Leishmania Poly(A) Binding Proteins reveals a direct association between PABP1, the RNA-binding protein RBP23 and mRNAs encoding ribosomal proteins (2021, PLoS neglected tropical diseases)
  • Genetic depletion of the RNA helicase DDX3 leads to impaired elongation of translating ribosomes triggering co-translational quality control of newly synthesized polypeptides (2021, Nucleic Acids Research)
  • New insights in the mode of action of anti-leishmanial drugs by using chemical mutagenesis screens coupled to next-generation sequencing (2020, Microbial Cell)
  • The AAA + ATPase valosin-containing protein (VCP)/p97/Cdc48 interaction network in Leishmania (2020, Scientific Reports)
  • In Vivo Tethering System to Isolate RNA-Binding Proteins Regulating mRNA Decay in Leishmania (2020, Methods in molecular biology)

The frequent collaborators found in Papadopoulou's publications include:

  • Gabriel Reis Ferreira
  • Philippe Leprohon
  • Prasad K. Padmanabhan
  • Carole Dumas
  • Marc Ouellette

Best Publications

  • Drug resistance and treatment failure in leishmaniasis: A 21st century challenge

    Alicia Ponte-Sucre;Francisco Gamarro;Jean-Claude Dujardin;Michael P. Barrett

  • Leishmaniasis: drugs in the clinic, resistance and new developments

    Marc Ouellette;Jolyne Drummelsmith;Barbara Papadopoulou

  • Disruption of the trypanothione reductase gene of Leishmania decreases its ability to survive oxidative stress in macrophages.

    Carole Dumas;Marc Ouellette;Jorge Tovar;Mark L. Cunningham

  • The Leishmania ATP-binding cassette protein PGPA is an intracellular metal-thiol transporter ATPase.

    Danielle Légaré;Dave Richard;Rita Mukhopadhyay;York-Dieter Stierhof

  • Developmental regulation of gene expression in trypanosomatid parasitic protozoa.

    Simon Haile;Barbara Papadopoulou

  • A novel antifolate resistance gene on the amplified H circle of Leishmania.

    B. Papadopoulou;G. Roy;M. Ouellette

  • Rab5 regulates the kiss and run fusion between phagosomes and endosomes and the acquisition of phagosome leishmanicidal properties in RAW 264.7 macrophages.

    S. Duclos;R. Diez;J. Garin;B. Papadopoulou

  • A combined proteomic and transcriptomic approach to the study of stage differentiation in Leishmania infantum

    François McNicoll;Jolyne Drummelsmith;Michaela Müller;Éric Madore

  • Modulation of gene expression in drug resistant Leishmania is associated with gene amplification, gene deletion and chromosome aneuploidy

    Jean-Michel Ubeda;Danielle Légaré;Frédéric Raymond;Amin Ahmed Ouameur

  • Episomal and stable expression of the luciferase reporter gene for quantifying Leishmania spp. infections in macrophages and in animal models.

    Gaétan Roy;Carole Dumas;Denis Sereno;Ying Wu

  • A common mechanism of stage-regulated gene expression in Leishmania mediated by a conserved 3'-untranslated region element.

    Nathalie Boucher;Ying Wu;Carole Dumas;Marthe Dubé

  • Genome sequencing of the lizard parasite Leishmania tarentolae reveals loss of genes associated to the intracellular stage of human pathogenic species

    Frédéric Raymond;Sébastien Boisvert;Gaétan Roy;Jean-François Ritt

  • An ATP-dependent As(III)-glutathione transport system in membrane vesicles of Leishmania tarentolae.

    Saibal Dey;Marc Ouellette;James Lightbody;Barbara Papadopoulou

  • Role of the ABC Transporter MRPA (PGPA) in Antimony Resistance in Leishmania infantum Axenic and Intracellular Amastigotes

    Karima El Fadili;Nadine Messier;Philippe Leprohon;Gaétan Roy

  • Live nonpathogenic parasitic vector as a candidate vaccine against visceral leishmaniasis.

    Marie Breton;Michel J Tremblay;Marc Ouellette;Barbara Papadopoulou

  • Genome-wide gene expression profiling analysis of Leishmania major and Leishmania infantum developmental stages reveals substantial differences between the two species

    Annie Rochette;Frédéric Raymond;Jean-Michel Ubeda;Martin Smith

  • Amplification of the ABC transporter gene PGPA and increased trypanothione levels in potassium antimonyl tartrate (SbIII) resistant Leishmania tarentolae.

    Anass Haimeur;Christian Brochu;Paul-André Genest;Barbara Papadopoulou

  • Mechanisms of drug resistance in Leishmania

    M. Ouellette;B. Papadopoulou

  • Genome-wide stochastic adaptive DNA amplification at direct and inverted DNA repeats in the parasite Leishmania.

    Jean-Michel Ubeda;Frédéric Raymond;Angana Mukherjee;Marie Plourde

  • A new developmentally regulated gene family in Leishmania amastigotes encoding a homolog of amastin surface proteins.

    Ying Wu;Youssef El Fakhry;Denis Sereno;Samira Tamar

  • Contribution of the Leishmania P-glycoprotein-related gene ltpgpA to oxyanion resistance.

    B. Papadopoulou;G. Roy;S. Dey;B.P. Rosen

Frequent Co-Authors

Marc Ouellette
Marc Ouellette Université Laval
Martin Olivier
Martin Olivier McGill University
Sima Rafati
Sima Rafati Pasteur Institute of Iran
Michel J. Tremblay
Michel J. Tremblay Université Laval
Jacques Corbeil
Jacques Corbeil Université Laval
Barry P. Rosen
Barry P. Rosen Florida International University
Martin A. Smith
Martin A. Smith Garvan Institute of Medical Research
Frédéric Bringaud
Frédéric Bringaud University of Bordeaux
Michel G. Bergeron
Michel G. Bergeron Université Laval
Najib M. El-Sayed
Najib M. El-Sayed University of Maryland, College Park

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