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Medicine

D-Index
81
Citations
25177
World Ranking
16594
National Ranking
8332

Overview

Robert P. Friedland is affiliated with the University of Louisville in the United States and has made contributions primarily in the field of Medicine, with a focus on subfields such as Neurology, Molecular Biology, Periodontics, Epidemiology, and Public Health, Environmental and Occupational Health.

The main topics covered in Friedland's research involve oral microbiology and periodontitis research, gut microbiota and health, tryptophan and brain disorders, Alzheimer's disease research and treatments, dementia and cognitive impairment research, iron metabolism and disorders, and trace elements in health.

Friedland has authored and co-authored numerous scientific papers, notable recent publications include:

  • What Are the Molecular Mechanisms by Which Functional Bacterial Amyloids Influence Amyloid Beta Deposition and Neuroinflammation in Neurodegenerative Disorders? (2020), International Journal of Molecular Sciences
  • Gut dysbiosis, defective autophagy and altered immune responses in neurodegenerative diseases: Tales of a vicious cycle (2021), Pharmacology & Therapeutics
  • The 2022 symposium on dementia and brain aging in low- and middle-income countries: Highlights on research, diagnosis, care, and impact (2024), Alzheimer s & Dementia
  • Oral Carriage of Streptococcus mutans Harboring the cnm Gene Relates to an Increased Incidence of Cerebral Microbleeds (2020), Stroke
  • Interplay of Ferritin Accumulation and Ferroportin Loss in Ageing Brain: Implication for Protein Aggregation in Down Syndrome Dementia, Alzheimer's, and Parkinson's Diseases (2022), International Journal of Molecular Sciences

Frequent co-authors working alongside Friedland include Masafumi Ihara, Shuichi Tonomura, Shuhei Ikeda, Yorito Hattori, and Masatoshi Koga.

Friedland's work has been published in a range of scientific venues, with repeated publications appearing in Alzheimer s & Dementia, Journal of Alzheimer s Disease, International Journal of Molecular Sciences, Frontiers in Aging Neuroscience, and Scientific Reports.

Additionally, Friedland has a book titled Unaging, published by Cambridge University Press in 2022.

Best Publications

  • Alzheimer's disease and vascular dementia in developing countries: prevalence, management, and risk factors

    Raj N. Kalaria;Gladys E. Maestre;Gladys E. Maestre;Raul Arizaga;Robert P. Friedland

  • The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

    Ekaterina Rogaeva;Ekaterina Rogaeva;Yan Meng;Joseph H. Lee;Yongjun Gu;Yongjun Gu

  • Cerebral glucose metabolism in childhood-onset obsessive-compulsive disorder.

    Susan E. Swedo;Mark B. Schapiro;Cheryl L. Grady;Deborah L. Cheslow

  • Depression as a risk factor for Alzheimer disease: the MIRAGE Study.

    Robert C. Green;L. Adrienne Cupples;Alex Kurz;Sanford Auerbach

  • Patients with Alzheimer's disease have reduced activities in midlife compared with healthy control-group members

    Robert P. Friedland;Thomas Fritsch;Kathleen A. Smyth;Elisabeth Koss

  • Regional cerebral metabolic alterations in dementia of the Alzheimer type: positron emission tomography with [18F]fluorodeoxyglucose.

    Robert P. Friedland;Thomas F. Budinger;Edward Ganz;Yukio Yano

  • Longitudinal study of the early neuropsychological and cerebral metabolic changes in dementia of the Alzheimer type

    Cheryl L. Grady;J. V. Haxby;B. Horwitz;M. Sundaram

  • Identification of vascular structures as a major source of signal contrast in high resolution 2D and 3D functional activation imaging of the motor cortex at l.5T preliminary results

    S. Lai;A. L. Hopkins;E. M. Haacke;D. Li

  • Meta-analysis confirms CR1, CLU, and PICALM as Alzheimer disease risk loci and reveals interactions with APOE genotypes.

    Gyungah Jun;Adam C. Naj;Gary W. Beecham;Li San Wang

  • Apolipoprotein E-epsilon4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimer's disease.

    D. R. D. Premkumar;D. L. Cohen;P. Hedera;R. P. Friedland

  • Neuroanatomical abnormalities in obsessive-compulsive disorder detected with quantitative X-ray computed tomography.

    Jay S. Luxenberg;Susan E. Swedo;Martine F. Flament;Robert P. Friedland

  • Neuronal Oxidative Stress Precedes Amyloid-β Deposition in Down Syndrome

    Akihiko Nunomura;Akihiko Nunomura;George Perry;Miguel A. Pappolla;Robert P. Friedland

  • Longitudinal study of cerebral metabolic asymmetries and associated neuropsychological patterns in early dementia of the Alzheimer type.

    James V. Haxby;Cheryl L. Grady;Elisabeth Koss;Barry Horwitz

  • Exposure to the Functional Bacterial Amyloid Protein Curli Enhances Alpha-Synuclein Aggregation in Aged Fischer 344 Rats and Caenorhabditis elegans.

    Shu G. Chen;Vilius Stribinskis;Madhavi J. Rane;Donald R. Demuth

  • Motor vehicle crashes in dementia of the Alzheimer type

    Robert P. Friedland;Elisabeth Koss;Anand Kumar;Sean Gaine

  • Retrieval from semantic memory in Alzheimer-type dementia

    Beth A. Ober;Nina F. Dronkers;Elisabeth Koss;Dean C. Delis

  • Cerebrospinal fluid production is reduced in healthy aging.

    C. May;J. A. Kaye;John R. Atack;M. B. Schapiro

  • Mechanisms of Molecular Mimicry Involving the Microbiota in Neurodegeneration

    Robert P. Friedland

  • Nicotine inhibits amyloid formation by the beta-peptide.

    Arthur R. Salomon;Keith J. Marcinowski;Robert P. Friedland;Michael G. Zagorski

  • Lack of association between angiotensin-converting enzyme and dementia of the Alzheimer’s type in an elderly Arab population in Wadi Ara, Israel

    Abdalla Bowirrat;Jing Cui;Kristin Waraska;Robert P Friedland

Frequent Co-Authors

Lindsay A. Farrer
Lindsay A. Farrer Boston University
George Perry
George Perry The University of Texas at San Antonio
Mark A. Smith
Mark A. Smith Case Western Reserve University
Stanley I. Rapoport
Stanley I. Rapoport National Institutes of Health
William J. Jagust
William J. Jagust University of California, Berkeley
Joseph C. LaManna
Joseph C. LaManna Case Western Reserve University
Jeffrey Kaye
Jeffrey Kaye Oregon Health & Science University
Amos D. Korczyn
Amos D. Korczyn Tel Aviv University
Clinton T. Baldwin
Clinton T. Baldwin Boston University
James V. Haxby
James V. Haxby Dartmouth College

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