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Clinton T. Baldwin

Clinton T. Baldwin

D-Index & Metrics

Genetics

D-Index
71
Citations
30223
World Ranking
2156
National Ranking
979

Overview

Clinton T. Baldwin is affiliated with Boston University in the United States and works primarily within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their research encompasses both broad and specialized areas, with a strong emphasis on Genetics and Molecular Biology. Additional subfields include Physiology, Psychiatry and Mental Health, and Neurology.

The main topics addressed in Baldwin's work include Genetic Associations and Epidemiology, Alzheimer's disease research and treatments, Dementia and Cognitive Impairment Research, Bioinformatics and Genomic Networks, Epigenetics and DNA Methylation, Diet and Metabolism Studies, and Machine Learning in Bioinformatics.

The scientist has contributed to multiple publications throughout their career. Notable recent papers include:

  • Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study, 2020, Nature Communications
  • Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90, 2022, Scientific Reports
  • Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK, GRB14, and KIAA0825 as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium, 2023, bioRxiv (Cold Spring Harbor Laboratory)
  • Amyloid-β predominant Alzheimer's disease neuropathologic change, 2024, Brain
  • Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease, 2025, Genome Biology

Baldwin has frequently collaborated with a core group of coauthors including Paul K. Crane, Joseph D. Buxbaum, Dennis W. Dickson, Liana G. Apostolova, and Lisa L. Barnes, each of whom have coauthored at least five publications with Baldwin.

The research outputs have appeared in several respected journals and venues, reflecting a diverse yet focused publication record. The most common publication venues include the Journal of Cystic Fibrosis, Nature Communications, Scientific Reports, Brain, and bioRxiv (Cold Spring Harbor Laboratory).

Best Publications

  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

    Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj

  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

    Adam C. Naj;Gyungah Jun;Gary W. Beecham;Li-San Wang

  • The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

    Ekaterina Rogaeva;Ekaterina Rogaeva;Yan Meng;Joseph H. Lee;Yongjun Gu;Yongjun Gu

  • Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

    Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • An exonic mutation in the HuP2 paired domain gene causes Waardenburg's syndrome

    Clinton T. Baldwin;Christopher F. Hoth;Jean A. Amos;Elias O. da-Silva

  • Fetal hemoglobin in sickle cell anemia

    Idowu Akinsheye;Abdulrahman Alsultan;Nadia Solovieff;Duyen Ngo

  • Genetic signatures of exceptional longevity in humans.

    Paola Sebastiani;Nadia Solovieff;Andrew T. DeWan;Kyle M. Walsh

  • Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms

    Maya Saleh;John P. Vaillancourt;Rona K. Graham;Matthew Huyck

  • Variants in the ATP-Binding Cassette Transporter (ABCA7), Apolipoprotein E ε4, and the Risk of Late-Onset Alzheimer Disease in African Americans

    Christiane Reitz;Gyungah Jun;Adam Naj;Ruchita Rajbhandary

  • Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

    Eric M Reiman;Joseph F Arboleda-Velasquez;Yakeel T Quiroz;Matthew J Huentelman

  • Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

    David C. Whitcomb;Jessica LaRusch;Alyssa M. Krasinskas;Lambertus Klei

  • Genetic dissection and prognostic modeling of overt stroke in sickle cell anemia

    Paola Sebastiani;Marco F Ramoni;Vikki Nolan;Clinton T Baldwin

  • Single base mutation in the type II procollagen gene (COL2A1) as a cause of primary osteoarthritis associated with a mild chondrodysplasia.

    Leena Ala-Kokko;Clinton T. Baldwin;Roland W. Moskowitz;Darwin J. Prockop

  • Mutations in the paired domain of the human PAX3 gene cause Klein-Waardenburg syndrome (WS-III) as well as Waardenburg syndrome type I (WS-I).

    C F Hoth;A Milunsky;N Lipsky;R Sheffer

  • Genome-wide association study of Alzheimer's disease

    M. I. Kamboh;F. Y. Demirci;X. Wang;R. L. Minster

  • A Comprehensive Genetic Association Study of Alzheimer Disease in African Americans

    Mark W. Logue;Matthew Schu;Badri N. Vardarajan;Jacki Buros

  • A genome-wide association study of post-traumatic stress disorder identifies the retinoid-related orphan receptor alpha (RORA) gene as a significant risk locus

    Mark W. Logue;Clinton Baldwin;Guia Guffanti;Efi Melista

  • Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases

    Giovanni Coppola;Subashchandrabose Chinnathambi;Jason Ji Yong Lee;Beth A. Dombroski

  • BCL11A is a major HbF quantitative trait locus in three different populations with β-hemoglobinopathies ☆

    Amanda E. Sedgewick;Nadia Timofeev;Paola Sebastiani;Jason C.C. So

Frequent Co-Authors

Lindsay A. Farrer
Lindsay A. Farrer Boston University
Martin H. Steinberg
Martin H. Steinberg Boston University
Kathryn L. Lunetta
Kathryn L. Lunetta Boston University
Anita L. DeStefano
Anita L. DeStefano Boston University
Robert C. Green
Robert C. Green Brigham and Women's Hospital
Badri N. Vardarajan
Badri N. Vardarajan Columbia University
Philip L. De Jager
Philip L. De Jager Columbia University
Peter St George-Hyslop
Peter St George-Hyslop Columbia University
Gerard D. Schellenberg
Gerard D. Schellenberg University of Pennsylvania
Margaret A. Pericak-Vance
Margaret A. Pericak-Vance University of Miami

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