Akihiko Nunomura mainly focuses on Oxidative stress, Alzheimer's disease, Disease, Biochemistry and Neuroscience. The Oxidative stress study combines topics in areas such as Neurodegeneration and Mitochondrion. His Alzheimer's disease study combines topics from a wide range of disciplines, such as NADPH oxidase and Immunology.
His studies deal with areas such as Oxidative phosphorylation, Downregulation and upregulation and Oxidative damage as well as Disease. His Biochemistry research is multidisciplinary, incorporating perspectives in Molecular biology and Microglia. His Neuroscience research is multidisciplinary, incorporating elements of Pathological, Pathogenesis and Senile plaques.
The scientist’s investigation covers issues in Oxidative stress, Alzheimer's disease, Disease, Neuroscience and Biochemistry. His Oxidative stress study combines topics from a wide range of disciplines, such as Reactive oxygen species, Oxidative phosphorylation, Mitochondrion and Pathology. His biological study spans a wide range of topics, including Neuropathology, Lipofuscin and Mitochondrial DNA.
His Alzheimer's disease research incorporates elements of Antioxidant, Bioinformatics, Neurodegeneration, Cell biology and Degenerative disease. Akihiko Nunomura interconnects RNA and 8-Hydroxyguanosine in the investigation of issues within Neurodegeneration. His work carried out in the field of Neuroscience brings together such families of science as Pathological and Function.
Oxidative stress, Alzheimer's disease, Neuroscience, Disease and Internal medicine are his primary areas of study. His Oxidative stress study improves the overall literature in Biochemistry. His studies deal with areas such as Hippocampal formation, Disease process, Cognitive impairment and Bioinformatics as well as Alzheimer's disease.
His Neuroscience research incorporates themes from Extracellular, Pathological, Neurodegeneration and Intracellular. His work deals with themes such as Immunology, Knockout mouse, Neuroprotection and Neuregulin 1, which intersect with Disease. His work in Internal medicine covers topics such as Endocrinology which are related to areas like Pharmacotherapy and Atrophy.
His primary scientific interests are in Alzheimer's disease, Neuroscience, Oxidative stress, RNA and Neurodegeneration. He has researched Alzheimer's disease in several fields, including Hippocampal formation, Neuropathology and Pathophysiology. In his study, Disease, Function, Phosphorylation, Mediator and Neuron is strongly linked to Extracellular, which falls under the umbrella field of Neuroscience.
His Oxidative stress study is concerned with the field of Biochemistry as a whole. His research investigates the connection between RNA and topics such as microRNA that intersect with problems in Messenger RNA, Molecular biology and Protein biosynthesis. Akihiko Nunomura combines subjects such as Temporal cortex, Neocortex, Cerebral cortex, Dementia and Hippocampus with his study of Neurodegeneration.
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Oxidative damage is the earliest event in Alzheimer disease.
Akihiko Nunomura;George Perry;Gjumrakch Aliev;Keisuke Hirai;Keisuke Hirai.
Journal of Neuropathology and Experimental Neurology (2001)
Mitochondrial abnormalities in Alzheimer's disease.
Keisuke Hirai;Gjumrakch Aliev;Akihiko Nunomura;Akihiko Nunomura;Hisashi Fujioka.
The Journal of Neuroscience (2001)
Oxidative stress in Alzheimer's disease.
Mark A. Smith;Catherine A. Rottkamp;Akihiko Nunomura;Arun K. Raina.
Biochimica et Biophysica Acta (2000)
RNA Oxidation Is a Prominent Feature of Vulnerable Neurons in Alzheimer's Disease
Akihiko Nunomura;George Perry;Miguel A. Pappolla;Ramon Wade.
The Journal of Neuroscience (1999)
Involvement of Oxidative Stress in Alzheimer Disease
Akihiko Nunomura;Rudy J. Castellani;Xiongwei Zhu;Paula I. Moreira.
Journal of Neuropathology and Experimental Neurology (2006)
Oxidative stress in Alzheimer disease: a possibility for prevention.
David J. Bonda;Xinglong Wang;George Perry;George Perry;Akihiko Nunomura.
Neuropharmacology (2010)
Evidence that the β-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of Aβ by zinc
Math P. Cuajungco;Lee E. Goldstein;Akihiko Nunomura;Mark A. Smith.
Journal of Biological Chemistry (2000)
Increased Iron and Free Radical Generation in Preclinical Alzheimer Disease and Mild Cognitive Impairment
Mark A. Smith;Xiongwei Zhu;Massimo Tabaton;Gang Liu.
Journal of Alzheimer's Disease (2010)
Role of mitochondrial dysfunction in Alzheimer's disease.
Rudy Castellani;Keisuke Hirai;Gjumrakch Aliev;Kelly L. Drew.
Journal of Neuroscience Research (2002)
Neuronal Oxidative Stress Precedes Amyloid-β Deposition in Down Syndrome
Akihiko Nunomura;Akihiko Nunomura;George Perry;Miguel A. Pappolla;Robert P. Friedland.
Journal of Neuropathology and Experimental Neurology (2000)
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