D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 74 Citations 21,628 184 World Ranking 15020 National Ranking 492

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

Akihiko Nunomura mainly focuses on Oxidative stress, Alzheimer's disease, Disease, Biochemistry and Neuroscience. The Oxidative stress study combines topics in areas such as Neurodegeneration and Mitochondrion. His Alzheimer's disease study combines topics from a wide range of disciplines, such as NADPH oxidase and Immunology.

His studies deal with areas such as Oxidative phosphorylation, Downregulation and upregulation and Oxidative damage as well as Disease. His Biochemistry research is multidisciplinary, incorporating perspectives in Molecular biology and Microglia. His Neuroscience research is multidisciplinary, incorporating elements of Pathological, Pathogenesis and Senile plaques.

His most cited work include:

  • Oxidative damage is the earliest event in Alzheimer disease. (1495 citations)
  • Mitochondrial abnormalities in Alzheimer's disease. (1051 citations)
  • Mitochondrial abnormalities in Alzheimer's disease. (1051 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Oxidative stress, Alzheimer's disease, Disease, Neuroscience and Biochemistry. His Oxidative stress study combines topics from a wide range of disciplines, such as Reactive oxygen species, Oxidative phosphorylation, Mitochondrion and Pathology. His biological study spans a wide range of topics, including Neuropathology, Lipofuscin and Mitochondrial DNA.

His Alzheimer's disease research incorporates elements of Antioxidant, Bioinformatics, Neurodegeneration, Cell biology and Degenerative disease. Akihiko Nunomura interconnects RNA and 8-Hydroxyguanosine in the investigation of issues within Neurodegeneration. His work carried out in the field of Neuroscience brings together such families of science as Pathological and Function.

He most often published in these fields:

  • Oxidative stress (70.37%)
  • Alzheimer's disease (65.08%)
  • Disease (44.97%)

What were the highlights of his more recent work (between 2010-2019)?

  • Oxidative stress (70.37%)
  • Alzheimer's disease (65.08%)
  • Neuroscience (29.63%)

In recent papers he was focusing on the following fields of study:

Oxidative stress, Alzheimer's disease, Neuroscience, Disease and Internal medicine are his primary areas of study. His Oxidative stress study improves the overall literature in Biochemistry. His studies deal with areas such as Hippocampal formation, Disease process, Cognitive impairment and Bioinformatics as well as Alzheimer's disease.

His Neuroscience research incorporates themes from Extracellular, Pathological, Neurodegeneration and Intracellular. His work deals with themes such as Immunology, Knockout mouse, Neuroprotection and Neuregulin 1, which intersect with Disease. His work in Internal medicine covers topics such as Endocrinology which are related to areas like Pharmacotherapy and Atrophy.

Between 2010 and 2019, his most popular works were:

  • Oxidative Damage to RNA in Aging and Neurodegenerative Disorders (116 citations)
  • Mitochondrial DNA Oxidative Damage and Repair in Aging and Alzheimer's Disease (83 citations)
  • The Earliest Stage of Cognitive Impairment in Transition From Normal Aging to Alzheimer Disease Is Marked By Prominent RNA Oxidation in Vulnerable Neurons (80 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

His primary scientific interests are in Alzheimer's disease, Neuroscience, Oxidative stress, RNA and Neurodegeneration. He has researched Alzheimer's disease in several fields, including Hippocampal formation, Neuropathology and Pathophysiology. In his study, Disease, Function, Phosphorylation, Mediator and Neuron is strongly linked to Extracellular, which falls under the umbrella field of Neuroscience.

His Oxidative stress study is concerned with the field of Biochemistry as a whole. His research investigates the connection between RNA and topics such as microRNA that intersect with problems in Messenger RNA, Molecular biology and Protein biosynthesis. Akihiko Nunomura combines subjects such as Temporal cortex, Neocortex, Cerebral cortex, Dementia and Hippocampus with his study of Neurodegeneration.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Oxidative damage is the earliest event in Alzheimer disease.

Akihiko Nunomura;George Perry;Gjumrakch Aliev;Keisuke Hirai;Keisuke Hirai.
Journal of Neuropathology and Experimental Neurology (2001)

2170 Citations

Mitochondrial abnormalities in Alzheimer's disease.

Keisuke Hirai;Gjumrakch Aliev;Akihiko Nunomura;Akihiko Nunomura;Hisashi Fujioka.
The Journal of Neuroscience (2001)

1530 Citations

Oxidative stress in Alzheimer's disease.

Mark A. Smith;Catherine A. Rottkamp;Akihiko Nunomura;Arun K. Raina.
Biochimica et Biophysica Acta (2000)

1054 Citations

RNA Oxidation Is a Prominent Feature of Vulnerable Neurons in Alzheimer's Disease

Akihiko Nunomura;George Perry;Miguel A. Pappolla;Ramon Wade.
The Journal of Neuroscience (1999)

880 Citations

Involvement of Oxidative Stress in Alzheimer Disease

Akihiko Nunomura;Rudy J. Castellani;Xiongwei Zhu;Paula I. Moreira.
Journal of Neuropathology and Experimental Neurology (2006)

686 Citations

Oxidative stress in Alzheimer disease: a possibility for prevention.

David J. Bonda;Xinglong Wang;George Perry;George Perry;Akihiko Nunomura.
Neuropharmacology (2010)

528 Citations

Evidence that the β-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of Aβ by zinc

Math P. Cuajungco;Lee E. Goldstein;Akihiko Nunomura;Mark A. Smith.
Journal of Biological Chemistry (2000)

528 Citations

Increased Iron and Free Radical Generation in Preclinical Alzheimer Disease and Mild Cognitive Impairment

Mark A. Smith;Xiongwei Zhu;Massimo Tabaton;Gang Liu.
Journal of Alzheimer's Disease (2010)

432 Citations

Role of mitochondrial dysfunction in Alzheimer's disease.

Rudy Castellani;Keisuke Hirai;Gjumrakch Aliev;Kelly L. Drew.
Journal of Neuroscience Research (2002)

418 Citations

Neuronal Oxidative Stress Precedes Amyloid-β Deposition in Down Syndrome

Akihiko Nunomura;Akihiko Nunomura;George Perry;Miguel A. Pappolla;Robert P. Friedland.
Journal of Neuropathology and Experimental Neurology (2000)

409 Citations

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