Her primary areas of study are Oxidative stress, Mitochondrion, Internal medicine, Endocrinology and Diabetes mellitus. Her biological study spans a wide range of topics, including Reactive oxygen species, Glutathione and Insulin. Her Mitochondrion study combines topics in areas such as Alzheimer's disease, Disease, Oxidative phosphorylation and Antioxidant.
Her work on Depolarization is typically connected to Adenine nucleotide as part of general Internal medicine study, connecting several disciplines of science. Her Endocrinology study focuses mostly on Streptozotocin and Carbohydrate metabolism. Her work on Type 2 diabetes as part of general Diabetes mellitus research is often related to Repolarization, thus linking different fields of science.
Her main research concerns Internal medicine, Endocrinology, Mitochondrion, Oxidative stress and Biochemistry. Her study looks at the relationship between Internal medicine and topics such as Diabetes mellitus, which overlap with Coenzyme Q – cytochrome c reductase. She combines subjects such as Calcium and Vitamin E with her study of Endocrinology.
Her studies in Mitochondrion integrate themes in fields like Oxidative phosphorylation, Pharmacology and Mitochondrial permeability transition pore. Her work deals with themes such as Disease, Antioxidant and Neuroprotection, which intersect with Oxidative stress. Her Biochemistry research includes elements of Biophysics and Respiration.
Maria S. Santos mostly deals with Internal medicine, Endocrinology, Mitochondrion, Insulin and Oxidative stress. Her Internal medicine research includes themes of Liraglutide, Type 2 diabetes and Respiratory chain. Her Endocrinology research is multidisciplinary, incorporating perspectives in Alzheimer's disease, Antioxidant and Cognitive decline.
Her Mitochondrion research incorporates themes from Pharmacology, Phosphorylation and Mitochondrial permeability transition pore. Her Insulin study combines topics from a wide range of disciplines, such as Incretin and Tau protein. When carried out as part of a general Oxidative stress research project, her work on Lipid peroxidation and Protein oxidation is frequently linked to work in Estrogen signaling and Adenine nucleotide, therefore connecting diverse disciplines of study.
Maria S. Santos spends much of her time researching Internal medicine, Endocrinology, Mitochondrion, Insulin and Type 2 diabetes. Her research in Internal medicine intersects with topics in GSK-3 and Bioinformatics. Many of her research projects under Endocrinology are closely connected to Life quality and Adenine nucleotide with Life quality and Adenine nucleotide, tying the diverse disciplines of science together.
Her work carried out in the field of Mitochondrion brings together such families of science as Oxidative stress, Respiration and Streptozotocin. Her Oxidative stress study incorporates themes from Respiratory chain, Glutathione-disulfide reductase activity, Mitochondrial respiratory chain and Recurrent hypoglycemia. Within one scientific family, she focuses on topics pertaining to Neuroprotection under Insulin, and may sometimes address concerns connected to Glucose homeostasis.
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Doxorubicin: The Good, the Bad and the Ugly Effect
Cristina Carvalho;Renato X. Santos;Susana Cardoso;Sonia Correia.
Current Medicinal Chemistry (2009)
Carvedilol-mediated antioxidant protection against doxorubicin-induced cardiac mitochondrial toxicity
Paulo J. Oliveira;James A. Bjork;Maria S. Santos;Richard L. Leino.
Toxicology and Applied Pharmacology (2004)
Brain mitochondrial dysfunction as a link between Alzheimer's disease and diabetes.
Paula I. Moreira;Maria S. Santos;Raquel Seiça;Catarina R. Oliveira.
Journal of the Neurological Sciences (2007)
Effects of hyperglycemia on sperm and testicular cells of Goto-Kakizaki and streptozotocin-treated rat models for diabetes
Sandra Amaral;António J. Moreno;Maria Sancha Santos;Raquel Seiça.
Theriogenology (2006)
Lipoic Acid and N-acetyl Cysteine Decrease Mitochondrial-Related Oxidative Stress in Alzheimer Disease Patient Fibroblasts
Paula I. Moreira;Peggy L.R. Harris;Xiongwei Zhu;Maria S. Santos.
Journal of Alzheimer's Disease (2007)
Insulin signaling, glucose metabolism and mitochondria: major players in Alzheimer's disease and diabetes interrelation.
Sónia C Correia;Renato X Santos;Cristina Carvalho;Susana Cardoso.
Brain Research (2012)
An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease.
Paula I Moreira;Ana I Duarte;Maria S Santos;A Cristina Rego.
Journal of Alzheimer's Disease (2009)
Involvement of Oxidative Stress on the Impairment of Energy Metabolism Induced by Aβ Peptides on PC12 Cells: Protection by Antioxidants
Cláudia Pereira;Maria Sancha Santos;Catarina Oliveira.
Neurobiology of Disease (1999)
Mitochondrially targeted effects of berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a) quinolizinium] on K1735-M2 mouse melanoma cells: comparison with direct effects on isolated mitochondrial fractions.
Gonçalo C. Pereira;Ana F. Branco;Júlio A.C. Matos;Sandro L. Pereira.
Journal of Pharmacology and Experimental Therapeutics (2007)
Alzheimer disease and the role of free radicals in the pathogenesis of the disease.
Paula I. Moreira;Maria S. Santos;Catarina R. Oliveira;Justin C. Shenk.
Cns & Neurological Disorders-drug Targets (2008)
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