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João Ramalho-Santos

João Ramalho-Santos

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
12861
World Ranking
14311
National Ranking
57

Overview

João Ramalho-Santos is affiliated with the University of Coimbra in Portugal and has contributed extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research primarily addresses areas within Reproductive Medicine, Public Health, Environmental and Occupational Health, Molecular Biology, Pediatrics, Perinatology and Child Health, and Physiology.

The scientist's work focuses on topics such as Reproductive Biology and Fertility, Sperm and Testicular Function, Ovarian Function and Disorders, Birth, Development, and Health, Pluripotent Stem Cells Research, Reproductive System and Pregnancy, and CRISPR and Genetic Engineering.

Among their recent publications are the following papers:

  • Fluorescent probes for the detection of reactive oxygen species in human spermatozoa, 2020, Asian Journal of Andrology
  • Insights from qualitative research on NAFLD awareness with a cohort of T2DM patients: time to go public with insulin resistance?, 2020, BMC Public Health
  • The impact of antisperm antibodies on human male reproductive function: an update, 2021, Reproduction
  • Mitochondria-Targeted Compounds to Assess and Improve Human Sperm Function, 2021, Antioxidants and Redox Signaling
  • Isolation of Extracellular Vesicles from Human Follicular Fluid: Size-Exclusion Chromatography versus Ultracentrifugation, 2023, Biomolecules

Frequent co-authors collaborating with João Ramalho-Santos include:

  • Anabela Marisa Azul
  • Teresa Almeida-Santos
  • Ana Paula Sousa
  • Mireia Alemany i Pagès
  • Maria Soares

The scientist has published multiple times in prominent venues such as:

  • WIREs Mechanisms of Disease
  • European Journal of Clinical Investigation
  • Biomolecules
  • Reproduction
  • Methods in molecular biology

João Ramalho-Santos also has a record of book publications predominantly through Imprensa da Universidade de Coimbra eBooks. Notable titles include:

  • A Healthy Liver Will Always Deliver! (2020)
  • La prochaine fois, pensez à ton foie! (2020)
  • Um Fígado Equilibrado é Meio Caminho Andado! (2020)
  • ¡Un Hígado Equilibrado Es Medio Camino Andado! (2020)
  • Un Fegato Sano Ti Porta Lontano! (2020)
  • Eine gesunde Leber - nicht nur was für Streber (2020)
  • Zdrowa wątroba przy długim życiu Cię zachowa! (2020)
  • Sigues metge del teu propi fetge! (2020)
  • Zdravá játra vždy splní své povinnosti! (2020)
  • Folias Mitocondriais: Uma Breve Viagem Sobre a Energia da Vida (2025)

Best Publications

  • Ubiquitin tag for sperm mitochondria

    Peter Sutovsky;Ricardo D. Moreno;João Ramalho-Santos;Tanja Dominko

  • Energy metabolism in human pluripotent stem cells and their differentiated counterparts.

    Sandra Varum;Ana S. B. Rodrigues;Michelle B. Moura;Olga Momcilovic

  • Chd1 regulates open chromatin and pluripotency of embryonic stem cells

    Alexandre Gaspar-Maia;Adi Alajem;Fanny Polesso;Rupa Sridharan

  • Mitochondria functionality and sperm quality

    Alexandra Amaral;Bárbara Lourenço;Mónica Marques;João Ramalho-Santos

  • Ubiquitinated Sperm Mitochondria, Selective Proteolysis, and the Regulation of Mitochondrial Inheritance in Mammalian Embryos

    Peter Sutovsky;Ricardo D. Moreno;João Ramalho-Santos;Tanja Dominko

  • Mitochondrial functionality in reproduction: from gonads and gametes to embryos and embryonic stem cells

    João Ramalho-Santos;Sandra Varum;Sandra Amaral;Paula C Mota

  • Diabetes and the impairment of reproductive function: possible role of mitochondria and reactive oxygen species.

    Sandra Amaral;Paulo J Oliveira;João Ramalho-Santos

  • A putative, ubiquitin-dependent mechanism for the recognition and elimination of defective spermatozoa in the mammalian epididymis.

    P. Sutovsky;R. Moreno;J. Ramalho-Santos;T. Dominko

  • The combined human sperm proteome: cellular pathways and implications for basic and clinical science

    Alexandra Amaral;Judit Castillo;João Ramalho-Santos;Rafael Oliva

  • The Expression of Mitochondrial DNA Transcription Factors during Early Cardiomyocyte In Vitro Differentiation from Human Embryonic Stem Cells

    Justin C. St. John;João Ramalho-Santos;Heather L. Gray;Patti Petrosko

  • Human sperm tail proteome suggests new endogenous metabolic pathways

    Alexandra Amaral;Judit Castillo;Josep Maria Estanyol;José Luís Ballescà

  • Unique checkpoints during the first cell cycle of fertilization after intracytoplasmic sperm injection in rhesus monkeys.

    Laura Hewitson;Tanja Dominko;Diana Takahashi;Crista Martinovich

  • Effects of hyperglycemia on sperm and testicular cells of Goto-Kakizaki and streptozotocin-treated rat models for diabetes

    Sandra Amaral;António J. Moreno;Maria Sancha Santos;Raquel Seiça

  • Parabens in male infertility-is there a mitochondrial connection?

    Renata S. Tavares;Fátima C. Martins;Paulo J. Oliveira;João Ramalho-Santos

  • Ubiquitination of prohibitin in mammalian sperm mitochondria: possible roles in the regulation of mitochondrial inheritance and sperm quality control.

    Winston E. Thompson;João Ramalho-Santos;Peter Sutovsky

  • Enhancement of human embryonic stem cell pluripotency through inhibition of the mitochondrial respiratory chain.

    S. Varum;O. Momčilović;C. Castro;A. Ben-Yehudah

  • Identification of Proteins Involved in Human Sperm Motility Using High-Throughput Differential Proteomics

    Alexandra Amaral;Carla Paiva;Claudio Attardo Parrinello;Josep Maria Estanyol

  • The expression of polymerase gamma and mitochondrial transcription factor A and the regulation of mitochondrial DNA content in mature human sperm

    Alexandra Amaral;João Ramalho-Santos;Justin C. St John

  • Ca2+ Signals Generated by CatSper and Ca2+ Stores Regulate Different Behaviors in Human Sperm

    Wardah Alasmari;Sarah Costello;Joao Correia;Senga K. Oxenham

  • Not all sperm are equal: functional mitochondria characterize a subpopulation of human sperm with better fertilization potential.

    Ana Paula Sousa;Alexandra Amaral;Marta Baptista;Renata Tavares

Frequent Co-Authors

Gerald Schatten
Gerald Schatten University of Pittsburgh
Paulo J. Oliveira
Paulo J. Oliveira University of Coimbra
Peter Sutovsky
Peter Sutovsky University of Missouri
Nejat Düzgüneş
Nejat Düzgüneş University of the Pacific
Shlomo Nir
Shlomo Nir Hebrew University of Jerusalem
Denis Wirtz
Denis Wirtz Johns Hopkins University
António J.M. Moreno
António J.M. Moreno University of Coimbra
Gary M. Wessel
Gary M. Wessel Brown University
Rafael Oliva
Rafael Oliva University of Barcelona
Edward K. L. Chan
Edward K. L. Chan University of Florida

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