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Biology and Biochemistry

D-Index
76
Citations
19295
World Ranking
5082
National Ranking
2433

Overview

Hisashi Fujioka is affiliated with Case Western Reserve University in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with significant focus on subfields such as Molecular Biology, Physiology, Neurology, Parasitology, and Immunology.

Fujioka's work covers a range of topics including Mitochondrial Function and Pathology, Alzheimer's disease research and treatments, Neuroinflammation and Neurodegeneration Mechanisms, Adipose Tissue and Metabolism, ATP Synthase and ATPases Research, Toxoplasma gondii Research Studies, and studies related to Tryptophan and brain disorders.

Frequent publication venues for Fujioka include Proceedings of the National Academy of Sciences, Journal of Cachexia Sarcopenia and Muscle, Cell Reports Medicine, Acta Neuropathologica Communications, and Nature Communications.

Key recent papers authored or coauthored by Fujioka include:

  • Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease, 2020, Science Advances
  • P7C3-A20 treatment one year after TBI in mice repairs the blood-brain barrier, arrests chronic neurodegeneration, and restores cognition, 2020, Proceedings of the National Academy of Sciences
  • BAM15-mediated mitochondrial uncoupling protects against obesity and improves glycemic control, 2020, EMBO Molecular Medicine
  • Lipids activate skeletal muscle mitochondrial fission and quality control networks to induce insulin resistance in humans, 2021, Metabolism
  • Mitochondrial uncoupling attenuates sarcopenic obesity by enhancing skeletal muscle mitophagy and quality control, 2022, Journal of Cachexia Sarcopenia and Muscle

Frequent coauthors in Fujioka's work include Andrew A. Pieper, Coral J. Cintrón-Pérez, Edwin Vázquez-Rosa, Emiko Miller, and Yeojung Koh. This suggests collaboration across various studies and projects related to their fields of expertise.

Best Publications

  • Mitochondrial abnormalities in Alzheimer's disease.

    Keisuke Hirai;Gjumrakch Aliev;Akihiko Nunomura;Akihiko Nunomura;Hisashi Fujioka

  • Amyloid-β overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

    Xinglong Wang;Bo Su;Sandra L. Siedlak;Paula I. Moreira

  • Complex Polymorphisms in an ∼330 kDa Protein Are Linked to Chloroquine-Resistant P. falciparum in Southeast Asia and Africa

    Xin-zhuan Su;Laura A. Kirkman;Hisashi Fujioka;Thomas E. Wellems

  • Bacteriome and Mycobiome Interactions Underscore Microbial Dysbiosis in Familial Crohn’s Disease

    G. Hoarau;Pranab Kumar Mukherjee;C. Gower-Rousseau;C. Hager

  • LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1

    Xinglong Wang;Michael H. Yan;Hisashi Fujioka;Jun Liu

  • Dynamin-Like Protein 1 Reduction Underlies Mitochondrial Morphology and Distribution Abnormalities in Fibroblasts from Sporadic Alzheimer’s Disease Patients

    Xinglong Wang;Bo Su;Hisashi Fujioka;Xiongwei Zhu

  • Microtubule Reduction in Alzheimer’s Disease and Aging Is Independent of τ Filament Formation

    Adam D. Cash;Gjumrakch Aliev;Sandra L. Siedlak;Akihiko Nunomura

  • The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity

    Wenzhang Wang;Luwen Wang;Junjie Lu;Sandra L Siedlak

  • Conservation of a Gliding Motility and Cell Invasion Machinery in Apicomplexan Parasites

    Stefan Kappe;Thomas Bruderer;Soren Gantt;Hisashi Fujioka

  • Alternative mutations at position 76 of the vacuolar transmembrane protein PfCRT are associated with chloroquine resistance and unique stereospecific quinine and quinidine responses in Plasmodium falciparum.

    Roland A. Cooper;Michael T. Ferdig;Xin-Zhuan Su;Lyann M. B. Ursos

  • Ribosomal RNA in Alzheimer Disease Is Oxidized by Bound Redox-active Iron

    Kazuhiro Honda;Mark A. Smith;Xiongwei Zhu;Diane Baus

  • Pfsbp1, a Maurer's cleft Plasmodium falciparum protein, is associated with the erythrocyte skeleton ☆

    Thierry Blisnick;Maria Eugenia Morales Betoulle;Jean-Christophe Barale;Pierrick Uzureau

  • Parkinson's disease–associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes

    Wenzhang Wang;Xinglong Wang;Hisashi Fujioka;Charles Hoppel

  • Impaired cytoadherence of Plasmodium falciparum-infected erythrocytes containing sickle hemoglobin

    Rushina Cholera;Nathaniel J. Brittain;Mark R. Gillrie;Tatiana M. Lopera-Mesa

  • Abnormal display of PfEMP-1 on erythrocytes carrying haemoglobin C may protect against malaria

    Rick M Fairhurst;Dror I Baruch;Nathaniel J Brittain;Graciela R Ostera

  • Myosin A tail domain interacting protein (MTIP) localizes to the inner membrane complex of Plasmodium sporozoites.

    Lawrence W. Bergman;Karine Kaiser;Hisashi Fujioka;Isabelle Coppens

  • Evolution of a unique Plasmodium falciparum chloroquine-resistance phenotype in association with pfcrt polymorphism in Papua New Guinea and South America.

    Rajeev K. Mehlotra;Hisashi Fujioka;Paul D. Roepe;Omar Janneh

  • Plasmodium gallinaceum: a refractory mechanism of ookinete killing in the mosquito, Anopheles gambiae.

    K.D. Vernick;H. Fujioka;D.C. Seeley;B. Tandler

  • Parkinson’s disease‐associated DJ‐1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction

    Xinglong Wang;Timothy G. Petrie;Yingchao Liu;Jun Liu

  • KLF2 and KLF4 control endothelial identity and vascular integrity

    Panjamaporn Sangwung;Guangjin Zhou;Lalitha Nayak;E. Ricky Chan

Frequent Co-Authors

Masamichi Aikawa
Masamichi Aikawa Tokai University
Charles L. Hoppel
Charles L. Hoppel Case Western Reserve University
Xiongwei Zhu
Xiongwei Zhu Case Western Reserve University
George Perry
George Perry The University of Texas at San Antonio
Bernard Tandler
Bernard Tandler Case Western Reserve University
Mukesh K. Jain
Mukesh K. Jain Brown University
Xinglong Wang
Xinglong Wang University of Arizona
Marcelo Jacobs-Lorena
Marcelo Jacobs-Lorena Johns Hopkins University
Nirbhay Kumar
Nirbhay Kumar George Washington University
Thomas E. Wellems
Thomas E. Wellems National Institutes of Health

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