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Marcelo Jacobs-Lorena

Marcelo Jacobs-Lorena

D-Index & Metrics

Biology and Biochemistry

D-Index
73
Citations
15592
World Ranking
6064
National Ranking
2854

Research.com Recognitions

  • 2009 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Marcelo Jacobs-Lorena is affiliated with Johns Hopkins University in the United States. Their research focuses primarily on the interaction between insects and microorganisms, as well as mosquito-borne diseases and control strategies.

Their work spans multiple fields of study, including:

  • Medicine
  • Agricultural and Biological Sciences
  • Biochemistry, Genetics and Molecular Biology

Within these broad areas, they have contributed notably to several subfields such as:

  • Public Health, Environmental and Occupational Health
  • Insect Science
  • Molecular Biology
  • Immunology
  • Epidemiology

Key topics in their research include:

  • Insect symbiosis and bacterial influences
  • Mosquito-borne diseases and control
  • Invertebrate Immune Response Mechanisms
  • Malaria Research and Control
  • Trypanosoma species research and implications
  • Insect Resistance and Genetics
  • CRISPR and Genetic Engineering

Marcelo Jacobs-Lorena's recent publications illustrate their work in these areas, with papers such as:

  • "A natural symbiotic bacterium drives mosquito refractoriness to Plasmodium infection via secretion of an antimalarial lipase" (2021, Nature Microbiology)
  • "Use of Microbiota to Fight Mosquito-Borne Disease" (2020, Frontiers in Genetics)
  • "Clock genes and environmental cues coordinate Anopheles pheromone synthesis, swarming, and mating" (2021, Science)
  • "Delftia tsuruhatensis TC1 symbiont suppresses malaria transmission by anopheline mosquitoes" (2023, Science)
  • "New weapons to fight malaria transmission: A historical view" (2022, Entomological Research)

The venues where Marcelo Jacobs-Lorena frequently publishes include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Zenodo (CERN European Organization for Nuclear Research)
  • Science
  • Entomological Research

They have collaborated repeatedly with a group of co-authors, notably:

  • Wei Huang
  • Joel Vega-Rodríguez
  • Sung-Jae Cha
  • Thiago Luiz Alves e Silva
  • Sibao Wang

In recognition of their scientific contributions, Marcelo Jacobs-Lorena was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2009.

Best Publications

  • Transgenic anopheline mosquitoes impaired in transmission of a malaria parasite

    Junitsu Ito;Anil Kumar Ghosh;Luciano A. Moreira;Ernst A. Wimmer

  • Bee Venom Phospholipase Inhibits Malaria Parasite Development in Transgenic Mosquitoes

    Luciano A. Moreira;Junitsu Ito;Anil Kumar Ghosh;Martin Devenport

  • Targeting Plasmodium ligands on mosquito salivary glands and midgut with a phage display peptide library

    Anil K. Ghosh;Paulo E. M. Ribolla;Paulo E. M. Ribolla;Marcelo Jacobs-Lorena

  • Fighting malaria with engineered symbiotic bacteria from vector mosquitoes

    Sibao Wang;Anil K. Ghosh;Nicholas Bongio;Kevin A. Stebbings;Kevin A. Stebbings

  • Development of Transgenic Fungi That Kill Human Malaria Parasites in Mosquitoes

    Weiguo Fang;Joel Vega-Rodríguez;Anil K. Ghosh;Marcelo Jacobs-Lorena

  • Robust gut-specific gene expression in transgenic Aedes aegypti mosquitoes

    Luciano A. Moreira;Marten J. Edwards;Faisal Adhami;Nijole Jasinskiene

  • Malaria Control with Genetically Manipulated Insect Vectors

    Luke Alphey;C. Ben Beard;Peter Billingsley;Maureen Coetzee

  • Initiation of Haemoglobin Synthesis by Methionyl-tRNA

    David Housman;Marcelo Jacobs-Lorena;U. L. Rajbhandary;Harvey F. Lodish

  • Mosquito transgenesis: what is the fitness cost?

    Mauro T. Marrelli;Cristina K. Moreira;David Kelly;Luke Alphey

  • Fitness of anopheline mosquitoes expressing transgenes that inhibit Plasmodium development.

    Luciano A. Moreira;Jing Wang;Frank H. Collins;Marcelo Jacobs-Lorena

  • Transgenic malaria-resistant mosquitoes have a fitness advantage when feeding on Plasmodium-infected blood

    Mauro T. Marrelli;Chaoyang Li;Chaoyang Li;Jason L. Rasgon;Marcelo Jacobs-Lorena

  • The Plasmodium bottleneck: malaria parasite losses in the mosquito vector.

    Ryan C Smith;Joel Vega-Rodríguez;Marcelo Jacobs-Lorena

  • Driving mosquito refractoriness to Plasmodium falciparum with engineered symbiotic bacteria.

    Sibao Wang;André L. A. Dos-Santos;Wei Huang;Kun Connie Liu

  • The Journey of the Malaria Parasite in the Mosquito: Hopes for the New Century

    A Ghosh;M.J Edwards;M Jacobs-Lorena

  • The peritrophic matrix of hematophagous insects.

    Li Shao;Martin Devenport;Marcelo Jacobs-Lorena

  • An immune-responsive serpin, SRPN6, mediates mosquito defense against malaria parasites

    Eappen G. Abraham;Sofia B. Pinto;Anil Ghosh;Dana L. Vanlandingham

  • Genetic approaches to interfere with malaria transmission by vector mosquitoes

    Sibao Wang;Marcelo Jacobs-Lorena

  • Rapid Induction by a Blood Meal of a Carboxypeptidase Gene in the Gut of the Mosquito Anopheles gambiae

    Marten J. Edwards;Francisco J. A. Lemos;Marilyn Donnelly-Doman;Marcelo Jacobs-Lorena

  • A type I peritrophic matrix protein from the malaria vector Anopheles gambiae binds to chitin. Cloning, expression, and characterization.

    Zhicheng Shen;Marcelo Jacobs-Lorena

  • Driving midgut-specific expression and secretion of a foreign protein in transgenic mosquitoes with AgAper1 regulatory elements

    E. G. Abraham;M. Donnelly-Doman;H. Fujioka;A. Ghosh

Frequent Co-Authors

Hisashi Fujioka
Hisashi Fujioka Case Western Reserve University
Fotis C. Kafatos
Fotis C. Kafatos Harvard University
Anthony A. James
Anthony A. James University of California, Irvine
Isabelle Coppens
Isabelle Coppens Johns Hopkins University
Blandine Franke-Fayard
Blandine Franke-Fayard Leiden University Medical Center
José M. C. Ribeiro
José M. C. Ribeiro National Institutes of Health
Chris J. Janse
Chris J. Janse Leiden University Medical Center
Mark A. Kay
Mark A. Kay Stanford University
Andrew P. Waters
Andrew P. Waters University of Glasgow
Frank H. Collins
Frank H. Collins University of Notre Dame

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