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George K. Christophides

George K. Christophides

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
18245
World Ranking
10603
National Ranking
808

Overview

George K. Christophides is affiliated with Imperial College London in the United Kingdom. Their academic work primarily spans the fields of Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Within these broader fields, their research delves into subfields such as Public Health, Environmental and Occupational Health, Molecular Biology, Immunology, Insect Science, and Parasitology.

The scientist's research topics include studies related to mosquito-borne diseases and control, invertebrate immune response mechanisms, malaria research and control, insect symbiosis and bacterial influences, CRISPR and genetic engineering, insect resistance and genetics, and genomics and phylogenetic studies.

Frequent collaborators in their work include Nikolai Windbichler, Dina Vlachou, Astrid Hoermann, Paolo Capriotti, and Tibebu Habtewold.

George K. Christophides has contributed to numerous research publications, frequently appearing in venues such as bioRxiv (Cold Spring Harbor Laboratory), Malaria Journal, Wellcome Open Research, Nucleic Acids Research, and Scientific Reports.

Notable recent papers include:

  • VEuPathDB: the eukaryotic pathogen, vector and host bioinformatics resource center, 2021, Nucleic Acids Research
  • VEuPathDB: the eukaryotic pathogen, vector and host bioinformatics resource center in 2023, 2023, Nucleic Acids Research
  • Climate change and human health in the Eastern Mediterranean and Middle East: Literature review, research priorities and policy suggestions, 2022, Environmental Research
  • Toward the Definition of Efficacy and Safety Criteria for Advancing Gene Drive-Modified Mosquitoes to Field Testing, 2020, Vector-Borne and Zoonotic Diseases
  • Gene drive mosquitoes can aid malaria elimination by retarding Plasmodium sporogonic development, 2022, Science Advances

Best Publications

  • The Genome Sequence of the Malaria Mosquito Anopheles gambiae

    Robert A. Holt;G. Mani Subramanian;Aaron Halpern;Granger G. Sutton

  • Immunity-Related Genes and Gene Families in Anopheles gambiae

    George K. Christophides;Evgeny Zdobnov;Carolina Barillas-Mury;Ewan Birney

  • A Comprehensive Survey of the Plasmodium Life Cycle by Genomic, Transcriptomic, and Proteomic Analyses

    Neil Hall;Marianna Karras;J. Dale Raine;Jane M. Carlton;Jane M. Carlton;Jane M. Carlton

  • Evolutionary Dynamics of Immune-Related Genes and Pathways in Disease-Vector Mosquitoes

    Robert M. Waterhouse;Evgenia V. Kriventseva;Stephan Meister;Zhiyong Xi

  • Comparative genome and proteome analysis of Anopheles gambiae and Drosophila melanogaster.

    Evgeny M. Zdobnov;Christian Von Mering;Ivica Letunic;David Torrents

  • Highly evolvable malaria vectors: The genomes of 16 Anopheles mosquitoes

    Daniel E. Neafsey;Robert M. Waterhouse;Mohammad R. Abai;Sergey S. Aganezov

  • Effects of mosquito genes on Plasmodium development.

    Mike A. Osta;George K. Christophides;Fotis C. Kafatos

  • Genome expression analysis of Anopheles gambiae: Responses to injury, bacterial challenge, and malaria infection

    George Dimopoulos;George K. Christophides;Stephan Meister;Jörg Schultz

  • The role of reactive oxygen species on Plasmodium melanotic encapsulation in Anopheles gambiae

    Sanjeev Kumar;George K. Christophides;Rafael Cantera;Bradley Charles

  • VEuPathDB: the eukaryotic pathogen, vector and host bioinformatics resource center.

    Beatrice Amos;Cristina Aurrecoechea;Matthieu Barba;Ana Barreto

  • Climate, environmental and socio-economic change: weighing up the balance in vector-borne disease transmission

    Paul E. Parham;Paul E. Parham;Joanna Waldock;Joanna Waldock;George K. Christophides;Deborah Hemming

  • Widespread divergence between incipient Anopheles gambiae species revealed by whole genome sequences

    M. K. N. Lawniczak;S. J. Emrich;A. K. Holloway;A. P. Regier

  • Comparative and functional genomics of the innate immune system in the malaria vector Anopheles gambiae.

    George K. Christophides;Dina Vlachou;Fotis C. Kafatos

  • Anopheles gambiae PGRPLC-Mediated Defense against Bacteria Modulates Infections with Malaria Parasites

    Stephan Meister;Bogos Agianian;Fanny Turlure;Angela Relógio

  • Immune signaling pathways regulating bacterial and malaria parasite infection of the mosquito Anopheles gambiae

    Stephan Meister;Stefan M. Kanzok;Xue-li Zheng;Coralia Luna

  • Leucine-Rich Repeat Protein Complex Activates Mosquito Complement in Defense Against Plasmodium Parasites

    Michael Povelones;Robert M. Waterhouse;Fotis C. Kafatos;George K. Christophides

  • VectorBase: a data resource for invertebrate vector genomics

    Daniel Lawson;Peter Arensburger;Peter Atkinson;Nora J. Besansky

  • Functional genomic analysis of midgut epithelial responses in Anopheles during Plasmodium invasion.

    Dina Vlachou;Timm Schlegelmilch;George K. Christophides;Fotis C. Kafatos

  • Gene expression in insecticide resistant and susceptible Anopheles gambiae strains constitutively or after insecticide exposure

    John Vontas;C. Blass;A. C. Koutsos;Jean-Philippe David

  • Effects of Mosquito Genes on Plasmodium Development

    Mike A.Osta;George K.Christophides;Fotis C.Kafatos;张亚晶

Frequent Co-Authors

Fotis C. Kafatos
Fotis C. Kafatos Imperial College London
Evgeny M. Zdobnov
Evgeny M. Zdobnov Swiss Institute of Bioinformatics
Fotis C. Kafatos
Fotis C. Kafatos Harvard University
Robert M. Waterhouse
Robert M. Waterhouse Swiss Institute of Bioinformatics
Frank H. Collins
Frank H. Collins University of Notre Dame
Marc A. T. Muskavitch
Marc A. T. Muskavitch Biogen (United States)
Christos Louis
Christos Louis University of Crete
Jos Lelieveld
Jos Lelieveld Max Planck Institute for Chemistry
Carolina Barillas-Mury
Carolina Barillas-Mury National Institutes of Health
Ewan Birney
Ewan Birney European Molecular Biology Laboratory

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