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Biology and Biochemistry

D-Index
65
Citations
15893
World Ranking
9118
National Ranking
701

Overview

Luke Alphey is affiliated with the University of York in the United Kingdom. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology; Agricultural and Biological Sciences; and Medicine. Within these broad areas, their work focuses extensively on subfields including Molecular Biology, Insect Science, Public Health, Environmental and Occupational Health, Genetics, and Infectious Diseases.

The scientist's research topics concentrate on several specialized areas such as CRISPR and Genetic Engineering, Insect symbiosis and bacterial influences, Mosquito-borne diseases and control, Insect Resistance and Genetics, Viral Infections and Vectors, Insect behavior and control techniques, and Plant Virus Research Studies.

Frequent coauthors in their work include Michelle A. E. Anderson, Tim Harvey-Samuel, Philip T. Leftwich, S Basu, and Joshua X. D. Ang.

Luke Alphey has contributed to multiple publication venues with a consistent presence in the following:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Scientific Reports
  • PLoS neglected tropical diseases
  • Proceedings of the National Academy of Sciences

Selected recent papers authored or coauthored by Luke Alphey include:

  • "Combating mosquito-borne diseases using genetic control technologies," 2021, Nature Communications
  • "Standardizing the definition of gene drive," 2020, Proceedings of the National Academy of Sciences
  • "Genetic Biocontrol for Invasive Species," 2020, Frontiers in Bioengineering and Biotechnology
  • "Core commitments for field trials of gene drive organisms," 2020, Science
  • "Quantifying and Modeling the Acquisition and Retention of Lumpy Skin Disease Virus by Hematophagus Insects Reveals Clinically but Not Subclinically Affected Cattle Are Promoters of Viral Transmission and Key Targets for Control of Disease Outbreaks," 2021, Journal of Virology

Best Publications

  • Insect population control using a dominant, repressible, lethal genetic system.

    Dean D. Thomas;Christl A. Donnelly;Roger J. Wood;Luke S. Alphey

  • Sterile-Insect Methods for Control of Mosquito-Borne Diseases: An Analysis

    Luke Alphey;Mark Benedict;Romeo Bellini;Gary G. Clark

  • Suppression of a Field Population of Aedes aegypti in Brazil by Sustained Release of Transgenic Male Mosquitoes.

    Danilo O. Carvalho;Andrew R. McKemey;Luiza Garziera;Renaud Lacroix

  • Late-acting dominant lethal genetic systems and mosquito control

    Hoang Kim Phuc;Morten H Andreasen;Rosemary S Burton;Céline Vass

  • Genetic control of mosquitoes

    Luke Alphey

  • Successful suppression of a field mosquito population by sustained release of engineered male mosquitoes

    Angela F Harris;Andrew R McKemey;Derric Nimmo;Zoe Curtis

  • Field performance of engineered male mosquitoes

    Angela F Harris;Derric Nimmo;Andrew R McKemey;Nick Kelly

  • Female-specific flightless phenotype for mosquito control

    Guoliang Fu;Rosemary S. Lees;Derric Nimmo;Diane Aw

  • Female-specific insect lethality engineered using alternative splicing

    Guoliang Fu;Kirsty C Condon;Matthew J Epton;Peng Gong

  • Malaria Control with Genetically Manipulated Insect Vectors

    Luke Alphey;C. Ben Beard;Peter Billingsley;Maureen Coetzee

  • Genetic elimination of dengue vector mosquitoes

    Megan R. Wise de Valdez;Derric Nimmo;John Betz;Hong-Fei Gong

  • Mosquito transgenesis: what is the fitness cost?

    Mauro T. Marrelli;Cristina K. Moreira;David Kelly;Luke Alphey

  • twine, a cdc25 homolog that functions in the male and female germline of Drosophila.

    Luke Alphey;Juan Jimenez;Helen White-Cooper;Iain Dawson

  • Open Field Release of Genetically Engineered Sterile Male Aedes aegypti in Malaysia

    Renaud Lacroix;Andrew R. McKemey;Norzahira Raduan;Lim Kwee Wee

  • Re-engineering the sterile insect technique

    Luke Alphey

  • A dominant lethal genetic system for autocidal control of the Mediterranean fruitfly

    Peng Gong;Matthew J Epton;Guoliang Fu;Sarah Scaife

  • Transcriptional and post-transcriptional control mechanisms coordinate the onset of spermatid differentiation with meiosis I in Drosophila

    Helen White-Cooper;Mireille A. Schäfer;Luke S. Alphey;Margaret T. Fuller

  • Is It Time for Synthetic Biodiversity Conservation

    Antoinette J. Piaggio;Gernot Segelbacher;Philip J. Seddon;Luke Alphey;Luke Alphey

  • Complementation of fission yeast cdc2ts and cdc25ts mutants identifies two cell cycle genes from Drosophila: a cdc2 homologue and string.

    J. Jimenez;L. Alphey;P. Nurse;D. M. Glover

  • High efficiency site‐specific genetic engineering of the mosquito genome

    D. D. Nimmo;L. Alphey;J. M. Meredith;P. Eggleston

Frequent Co-Authors

Anthony A. James
Anthony A. James University of California, Irvine
Michael B. Bonsall
Michael B. Bonsall University of Oxford
Christl A. Donnelly
Christl A. Donnelly University of Oxford
David M. Glover
David M. Glover California Institute of Technology
John Vontas
John Vontas Foundation for Research and Technology Hellas
Andrea Crisanti
Andrea Crisanti University of Padua
Paul Reiter
Paul Reiter Institut Pasteur
Pattamaporn Kittayapong
Pattamaporn Kittayapong Mahidol University
Omar S. Akbari
Omar S. Akbari University of California, San Diego
Simon Gubbins
Simon Gubbins The Pirbright Institute

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