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Biology and Biochemistry

D-Index
52
Citations
15961
World Ranking
16464
National Ranking
309

Overview

Sanjiv A. Luther is affiliated with the University of Lausanne in Switzerland. Their research predominantly spans the fields of Immunology and Microbiology, Medicine, and Biochemistry, Genetics and Molecular Biology. Within these, the main subfields of study include Immunology, Oncology, Molecular Biology, Cell Biology, and Surgery.

The scientist's work focuses on several key topics, including:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • IL-33, ST2, and ILC Pathways
  • CAR-T cell therapy research
  • Immunotherapy and Immune Responses
  • Cellular Mechanics and Interactions
  • Hippo pathway signaling and YAP/TAZ

Several recent papers by Sanjiv A. Luther highlight contributions to immunological research:

  • "Central memory CD8+ T cells derive from stem-like Tcf7hi effector cells in the absence of cytotoxic differentiation" (2020), published in Immunity
  • "FOXC2 controls adult lymphatic endothelial specialization, function, and gut lymphatic barrier preventing multiorgan failure" (2021), published in Science Advances
  • "ADAMTS18+ villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels" (2022), published in Nature Communications
  • "Multitier mechanics control stromal adaptations in the swelling lymph node" (2022), published in Nature Immunology
  • "The alarmin interleukin-33 promotes the expansion and preserves the stemness of Tcf-1+ CD8+ T cells in chronic viral infection" (2023), published in Immunity

The scientist frequently collaborates with other researchers, including:

  • Nagham Alouche
  • Léonardo Scarpellino
  • Tatiana V. Petrova
  • Burkhard Ludewig
  • Mauro Delorenzi

Primary venues for publication include bioRxiv (Cold Spring Harbor Laboratory), Immunity, Nature Immunology, Proceedings of the National Academy of Sciences, and Science Advances.

Best Publications

  • A chemokine-driven positive feedback loop organizes lymphoid follicles

    K M Ansel;V N Ngo;P L Hyman;S A Luther

  • Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy.

    Imran Siddiqui;Karin Schaeuble;Vijaykumar Chennupati;Silvia A. Fuertes Marraco

  • Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells.

    Alexander Link;Tobias K Vogt;Stéphanie Favre;Mirjam R Britschgi

  • Chemokines as regulators of T cell differentiation

    Sanjiv A. Luther;Jason G. Cyster

  • Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in the plt/plt mouse.

    S. A. Luther;H. L. Tang;P. L. Hyman;A. G. Farr

  • Differing Activities of Homeostatic Chemokines CCL19, CCL21, and CXCL12 in Lymphocyte and Dendritic Cell Recruitment and Lymphoid Neogenesis

    Sanjiv A. Luther;Afshin Bidgol;Diana C. Hargreaves;Andrea Schmidt

  • Interstitial dendritic cell guidance by haptotactic chemokine gradients.

    Michele Weber;Robert Hauschild;Jan Schwarz;Christine Moussion

  • Follicular stromal cells and lymphocyte homing to follicles.

    J. G. Cyster;K. M. Ansel;K. Reif;E. H. Ekland

  • BLC expression in pancreatic islets causes B cell recruitment and lymphotoxin-dependent lymphoid neogenesis.

    Sanjiv A Luther;Theresa Lopez;Wei Bai;Douglas Hanahan

  • Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease.

    Karl S Lang;Mike Recher;Tobias Junt;Alexander A Navarini

  • Restoration of lymphoid organ integrity through the interaction of lymphoid tissue-inducer cells with stroma of the T cell zone.

    Elke Scandella;Beatrice Bolinger;Evelyn Lattmann;Simone Miller

  • Single-Cell RNA Sequencing of Lymph Node Stromal Cells Reveals Niche-Associated Heterogeneity

    Lauren B. Rodda;Erick Lu;Mariko L. Bennett;Caroline L. Sokol

  • The changing preference of T and B cells for partners as T-dependent antibody responses develop

    I. C. M. Maclennan;A. Gulbranson-Judge;K.-M. Toellner;M. Casamayor-Palleja

  • T Helper 1 (Th1) and Th2 Characteristics Start to Develop During T Cell Priming and Are Associated with an Immediate Ability to Induce Immunoglobulin Class Switching

    Kai-Michael Toellner;Sanjiv A. Luther;Daniel M.-Y. Sze;Richard K.-W. Choy

  • Overlapping Roles of CXCL13, Interleukin 7 Receptor α, and CCR7 Ligands in Lymph Node Development

    Sanjiv A. Luther;K. Mark Ansel;Jason G. Cyster

  • Maturation of Lymph Node Fibroblastic Reticular Cells from Myofibroblastic Precursors Is Critical for Antiviral Immunity

    Qian Chai;Lucas Onder;Elke Scandella;Cristina Gil-Cruz

  • IL-22 regulates lymphoid chemokine production and assembly of tertiary lymphoid organs.

    Francesca Barone;Francesca Barone;Saba Nayar;Saba Nayar;Joana Campos;Joana Campos;Thomas Cloake;Thomas Cloake

  • Stromal Fibroblasts in Tertiary Lymphoid Structures: A Novel Target in Chronic Inflammation

    Francesca Barone;David H. Gardner;Saba Nayar;Nathalie Steinthal

  • DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport

    Jeremiah Bernier-Latmani;Christophe Cisarovsky;Cansaran Saygili Demir;Marine Bruand

  • Fluid Flow Regulates Stromal Cell Organization and CCL21 Expression in a Tissue-Engineered Lymph Node Microenvironment

    Alice A. Tomei;Stefanie Siegert;Mirjam R. Britschgi;Sanjiv A. Luther

Frequent Co-Authors

Christopher D. Buckley
Christopher D. Buckley University of Oxford
Hans Acha-Orbea
Hans Acha-Orbea University of Lausanne
Jason G. Cyster
Jason G. Cyster University of California, San Francisco
Fabienne Tacchini-Cottier
Fabienne Tacchini-Cottier University of Lausanne
Burkhard Ludewig
Burkhard Ludewig University of Zurich
Freddy Radtke
Freddy Radtke École Polytechnique Fédérale de Lausanne
Nicola L. Harris
Nicola L. Harris Monash University
H. Robson MacDonald
H. Robson MacDonald University of Lausanne
Dietmar Zehn
Dietmar Zehn Technical University of Munich
Kai-Michael Toellner
Kai-Michael Toellner University of Birmingham

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