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D-Index & Metrics

Immunology

D-Index
50
Citations
13605
World Ranking
4198
National Ranking
277

Overview

Dietmar Zehn is affiliated with the Technical University of Munich in Germany and has a research focus primarily in Immunology and Microbiology, with significant contributions to Medicine. Their scholarly work spans multiple subfields including Immunology, Oncology, Epidemiology, Molecular Biology, and Hepatology.

The scientist's research covers several main topics including Immune Cell Function and Interaction, T-cell and B-cell Immunology, Immunotherapy and Immune Responses, CAR-T cell therapy research, Cancer Immunotherapy and Biomarkers, Hepatitis B Virus Studies, and Liver Disease Diagnosis and Treatment.

Frequent publication venues for Dietmar Zehn include Nature Immunology, Nature, bioRxiv (Cold Spring Harbor Laboratory), Immunity, and Nature Communications. Their work consists of multiple papers across these respected journals, indicating an active research presence in the field of immunology and related biomedical sciences.

  • 'Stem-like' precursors are the fount to sustain persistent CD8+ T cell responses (2022, Nature Immunology)
  • Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH (2021, Nature)
  • MYB orchestrates T cell exhaustion and response to checkpoint inhibition (2022, Nature)
  • Functional T cells are capable of supernumerary cell division and longevity (2023, Nature)
  • PGE2 limits effector expansion of tumour-infiltrating stem-like CD8+ T cells (2024, Nature)

Dietmar Zehn has collaborated frequently with several researchers, highlighting a network of recurring scientific partnerships. These coauthors include Percy A. Knolle, Christine Wurmser, Sainitin Donakonda, Ulrike Protzer, and Gustavo Pereira de Almeida. The collaborations are indicative of ongoing work in shared research areas within immunology and related disciplines.

Best Publications

  • Defining ‘T cell exhaustion’

    Christian U Blank;W Nicholas Haining;Werner Held;Patrick G Hogan;Patrick G Hogan

  • T Cell Factor 1-Expressing Memory-like CD8+ T Cells Sustain the Immune Response to Chronic Viral Infections

    Daniel T. Utzschneider;Mélanie Charmoy;Vijaykumar Chennupati;Laurène Pousse

  • TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection.

    Francesca Alfei;Kristiyan Kanev;Maike Hofmann;Ming Wu

  • Complete but curtailed T-cell response to very low-affinity antigen

    Unknown

  • Transcription factor IRF4 Promotes CD8 + T cell exhaustion and limits the development of memory-like T cells during chronic infection

    Kevin Man;Sarah S. Gabriel;Yang Liao;Yang Liao;Renee Gloury;Renee Gloury

  • Precursor exhausted T cells: key to successful immunotherapy?

    Axel Kallies;Dietmar Zehn;Daniel T Utzschneider

  • Auto-aggressive CXCR6 + CD8 T cells cause liver immune pathology in NASH

    Michael Dudek;Dominik Pfister;Sainitin Donakonda;Pamela Filpe

  • T Cells with Low Avidity for a Tissue-Restricted Antigen Routinely Evade Central and Peripheral Tolerance and Cause Autoimmunity

    Dietmar Zehn;Michael J. Bevan

  • MicroRNA-155 Is Required for Effector CD8+ T Cell Responses to Virus Infection and Cancer

    Jan C. Dudda;Bruno Salaun;Yun Ji;Douglas C. Palmer

  • T cell differentiation in chronic infection and cancer: functional adaptation or exhaustion?

    Daniel E. Speiser;Daniel T. Utzschneider;Susanne G. Oberle;Christian Münz

  • T cells maintain an exhausted phenotype after antigen withdrawal and population reexpansion

    Daniel T Utzschneider;Amandine Legat;Silvia A Fuertes Marraco;Lucie Carrié

  • Acetate Promotes T Cell Effector Function during Glucose Restriction

    Jing Qiu;Matteo Villa;David E. Sanin;Michael D. Buck

  • Inhibitory Receptor Expression Depends More Dominantly on Differentiation and Activation than "Exhaustion" of Human CD8 T Cells.

    Amandine Legat;Daniel E. Speiser;Hanspeter Pircher;Dietmar Zehn

  • One naive T cell, multiple fates in CD8+ T cell differentiation

    Carmen Gerlach;Jeroen W.J. van Heijst;Erwin Swart;Daoud Sie

  • ‘Stem-like’ precursors are the fount to sustain persistent CD8+ T cell responses

    Unknown

  • TCF1+ hepatitis C virus-specific CD8+ T cells are maintained after cessation of chronic antigen stimulation.

    Dominik Wieland;Janine Kemming;Anita Schuch;Florian Emmerich

  • T Cell Affinity Regulates Asymmetric Division, Effector Cell Differentiation, and Tissue Pathology

    Carolyn G. King;Sabrina Koehli;Barbara Hausmann;Mathias Schmaler

  • Bystander-Activated Memory CD8 T Cells Control Early Pathogen Load in an Innate-like, NKG2D-Dependent Manner

    Talyn Chu;Aaron J. Tyznik;Sarah Roepke;Amy M. Berkley

  • MYB orchestrates T cell exhaustion and response to checkpoint inhibition

    Unknown

  • Autoreactive T cells bypass negative selection and respond to self-antigen stimulation during infection

    Sarah Enouz;Lucie Carrié;Doron Merkler;Doron Merkler;Michael J. Bevan

  • High antigen levels induce an exhausted phenotype in a chronic infection without impairing T cell expansion and survival.

    Daniel T Utzschneider;Francesca Alfei;Patrick Roelli;Patrick Roelli;David Barras

  • Shp-2 Is Dispensable for Establishing T Cell Exhaustion and for PD-1 Signaling In Vivo

    Giorgia Rota;Charlène Niogret;Anh Thu Dang;Cristina Ramon Barros

  • Antigen affinity and antigen dose exert distinct influences on CD4 T-cell differentiation.

    Simone Keck;Mathias Schmaler;Stefan Ganter;Lena Wyss

Frequent Co-Authors

Daniel E. Speiser
Daniel E. Speiser University of Lausanne
Werner Held
Werner Held University of Lausanne
Percy A. Knolle
Percy A. Knolle Technical University of Munich
Doron Merkler
Doron Merkler University of Geneva
Mauro Delorenzi
Mauro Delorenzi University of Lausanne
Robert Thimme
Robert Thimme University of Freiburg
Michael J. Bevan
Michael J. Bevan University of Washington
Joshua T. Schiffer
Joshua T. Schiffer Fred Hutchinson Cancer Research Center
Marc Pellegrini
Marc Pellegrini Walter and Eliza Hall Institute of Medical Research
Axel Kallies
Axel Kallies University of Melbourne

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