2018 - Fellow of the American Association for the Advancement of Science (AAAS)
John T. Patton mainly focuses on RNA, Rotavirus, Virology, Genetics and Viral replication. His work on RNA-dependent RNA polymerase as part of general RNA study is frequently linked to RNA silencing, bridging the gap between disciplines. His primary area of study in Rotavirus is in the field of NSP1.
His research investigates the link between Virology and topics such as RNase P that cross with problems in Mutant, Ribonuclease and Innate immune system. His work in Reoviridae, Genome, Gene and Viral protein are all subfields of Genetics research. His Molecular biology research includes elements of NALP3 and Sense.
His scientific interests lie mostly in Virology, RNA, Rotavirus, Molecular biology and Genetics. He combines subjects such as Genome and Recombinant DNA with his study of Virology. His work in the fields of RNA-dependent RNA polymerase and RNA polymerase overlaps with other areas such as RNA silencing.
His research in the fields of NSP1 overlaps with other disciplines such as Histone octamer. His work carried out in the field of Molecular biology brings together such families of science as Messenger RNA, Gene expression, Viral protein and Biochemistry. His Gene, Genotype, Phylogenetics and Peptide sequence study, which is part of a larger body of work in Genetics, is frequently linked to Reassortment, bridging the gap between disciplines.
His primary areas of investigation include Virology, Rotavirus, Recombinant DNA, Virus and NSP1. His Virology study incorporates themes from Reverse genetics and RNA, RNA virus. His RNA research incorporates elements of T7 RNA polymerase, Innate immune system and Viral replication.
His research integrates issues of Epitope, Antibody, Immune system and Sequence alignment in his study of Rotavirus. His Reoviridae study results in a more complete grasp of Genetics. His work on Gene, Genotype and Human genetics as part of general Genetics study is frequently linked to Reassortment, bridging the gap between disciplines.
Virology, Rotavirus, NSP1, Reoviridae and Genetics are his primary areas of study. His Virology study focuses on Virus in particular. His Rotavirus study combines topics from a wide range of disciplines, such as Pathogen and Virulence.
His studies deal with areas such as Protein structure, Molecular biology, IRF1 and Proteasome as well as NSP1. His study in Reoviridae is interdisciplinary in nature, drawing from both RNA and Viral replication. His Gene and Genotype study in the realm of Genetics connects with subjects such as Reassortment.
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Uniformity of rotavirus strain nomenclature proposed by the Rotavirus Classification Working Group (RCWG).
Jelle Matthijnssens;Max Ciarlet;Sarah M. McDonald;Houssam Attoui.
Archives of Virology (2011)
Full Genome-Based Classification of Rotaviruses Reveals a Common Origin between Human Wa-Like and Porcine Rotavirus Strains and Human DS-1-Like and Bovine Rotavirus Strains
Jelle Matthijnssens;Max Ciarlet;Erica Heiman;Ingrid Arijs.
Journal of Virology (2008)
Critical Role for Cryopyrin/Nalp3 in Activation of Caspase-1 in Response to Viral Infection and Double-stranded RNA
Thirumala Devi Kanneganti;Mathilde Body-Malapel;Amal Amer;Jong Hwan Park.
Journal of Biological Chemistry (2006)
Recommendations for the classification of group A rotaviruses using all 11 genomic RNA segments.
Jelle Matthijnssens;Max Ciarlet;Mustafizur Rahman;Mustafizur Rahman;Houssam Attoui.
Archives of Virology (2008)
Rotavirus nonstructural protein 1 subverts innate immune response by inducing degradation of IFN regulatory factor 3.
Mario Barro;John T. Patton.
Proceedings of the National Academy of Sciences of the United States of America (2005)
Rotavirus NSP1 Inhibits Expression of Type I Interferon by Antagonizing the Function of Interferon Regulatory Factors IRF3, IRF5, and IRF7
Mario Barro;John T. Patton.
Journal of Virology (2007)
Rotavirus Replication: Plus-Sense Templates for Double-Stranded RNA Synthesis Are Made in Viroplasms
Lynn S. Silvestri;Zenobia F. Taraporewala;John T. Patton.
Journal of Virology (2004)
Evolutionary Dynamics of Human Rotaviruses: Balancing Reassortment with Preferred Genome Constellations
Sarah M. McDonald;Jelle Matthijnssens;John K. McAllen;Erin Hine.
PLOS Pathogens (2009)
N protein alone satisfies the requirement for protein synthesis during RNA replication of vesicular stomatitis virus.
J T Patton;N L Davis;G W Wertz.
Journal of Virology (1984)
Structural insights into the coupling of virion assembly and rotavirus replication
Shane D Trask;Sarah M McDonald;John T Patton.
Nature Reviews Microbiology (2012)
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