World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
124
Citations
56138
World Ranking
527
National Ranking
329

Research.com Recognitions

  • 2021 - Sedgwick Memorial Medal, American Public Health Association
  • 2021 - Potamkin Prize for Research in Pick's, Alzheimer's, and Related Diseases, American Academy of Neurology
  • 2017 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Kenneth S. Kosik is affiliated with the University of California, Santa Barbara in the United States. Their research spans multiple fields including Medicine, Biochemistry, Genetics and Molecular Biology, and Neuroscience. Subfields of their work include Molecular Biology, Physiology, Neurology, Cognitive Neuroscience, and Infectious Diseases.

The main topics covered in their research are:

  • Alzheimer's disease research and treatments
  • Dementia and Cognitive Impairment Research
  • Neural dynamics and brain function
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neuroscience and Neural Engineering
  • RNA Research and Splicing
  • SARS-CoV-2 detection and testing

Kosik has published extensively in several scientific venues. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Alzheimer s & Dementia
  • Nature Communications
  • Scientific Reports
  • Nature

Among recent papers, the following are notable for publication year and venue:

  • Tau PTM Profiles Identify Patient Heterogeneity and Stages of Alzheimer's Disease, 2020, Cell
  • LRP1 is a master regulator of tau uptake and spread, 2020, Nature
  • Human neural tube morphogenesis in vitro by geometric constraints, 2021, Nature
  • Functional neuronal circuitry and oscillatory dynamics in human brain organoids, 2022, Nature Communications
  • Resilience to autosomal dominant Alzheimer's disease in a Reelin-COLBOS heterozygous man, 2023, Nature Medicine

Their research collaborations include frequent co-authors such as:

  • Francisco Lopera
  • David Aguillón
  • Juliana Acosta-Uribe
  • Bruce L. Miller
  • Yakeel T. Quiroz

Kenneth S. Kosik has received several awards including:

  • Potamkin Prize for Research in Pick's, Alzheimer's, and Related Diseases, American Academy of Neurology (2021)
  • Sedgwick Memorial Medal, American Public Health Association (2021)
  • Fellow of the American Association for the Advancement of Science (AAAS) (2017)

Best Publications

  • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells.

    Jennifer A. Chan;Anna M. Krichevsky;Kenneth S. Kosik

  • Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease

    Kenneth S. Kosik;Catharine L. Joachim;Dennis J. Selkoe

  • Ubiquitination of a New Form of α-Synuclein by Parkin from Human Brain: Implications for Parkinson's Disease

    Hideki Shimura;Michael G. Schlossmacher;Nobutaka Hattori;Matthew P. Frosch

  • MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells.

    Na Xu;Thales Papagiannakopoulos;Guangjin Pan;James A. Thomson

  • A microRNA array reveals extensive regulation of microRNAs during brain development

    Anna M. Krichevsky;Kevin S. King;Christine P. Donahue;Konstantin Khrapko

  • The Amphimedon queenslandica genome and the evolution of animal complexity

    Mansi Srivastava;Oleg Simakov;Oleg Simakov;Jarrod Chapman;Bryony Fahey

  • The neuronal microRNA system.

    Kenneth S. Kosik

  • Specific MicroRNAs Modulate Embryonic Stem Cell–Derived Neurogenesis

    Anna M. Krichevsky;Kai‐C. Sonntag;Ole Isacson;Kenneth S. Kosik

  • MicroRNA-21 Targets a Network of Key Tumor-Suppressive Pathways in Glioblastoma Cells

    Thales Papagiannakopoulos;Alice Shapiro;Kenneth S. Kosik

  • Inhibition of neurite polarity by tau antisense oligonucleotides in primary cerebellar neurons

    Alfredo Caceres;Kenneth S. Kosik;Kenneth S. Kosik

  • Structure and novel exons of the human tau gene.

    Athena Andreadis;William M. Brown;Kenneth S. Kosik

  • Identification of many microRNAs that copurify with polyribosomes in mammalian neurons

    John Kim;Anna Krichevsky;Yonatan Grad;Gabriel D. Hayes

  • Developmentally regulated expression of specific tau sequences.

    Kenneth S. Kosik;Lisa D. Orecchio;Lisa D. Orecchio;Shelley Bakalis;Shelley Bakalis;Rachael L. Neve;Rachael L. Neve

  • Identification of cDNA clones for the human microtubule-associated protein tau and chromosomal localization of the genes for tau and microtubule-associated protein 2

    Rachael L. Neve;Rachael L. Neve;Peter C Harris;Peter C Harris;Kenneth S. Kosik;David M. Kurnit;David M. Kurnit

  • The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology.

    Lemere Ca;Lopera F;Kosik Ks;Lendon Cl

  • Neuronal RNA granules: a link between RNA localization and stimulation-dependent translation.

    Anna M Krichevsky;Kenneth S Kosik

  • The microtubule binding domain of tau protein

    Gloria Lee;Gloria Lee;Rachael L. Neve;Rachael L. Neve;Kenneth S. Kosik;Kenneth S. Kosik

  • Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study

    Eric M Reiman;Yakeel T Quiroz;Yakeel T Quiroz;Adam S Fleisher;Kewei Chen

  • Epitopes that span the tau molecule are shared with paired helical filaments

    K.S. Kosik;L.D. Orecchio;L. Binder;J.Q. Trojanowski

  • A detergent-insoluble membrane compartment contains Aβ in vivo

    Seung Jae Lee;Udaya Liyanage;Perry E. Bickel;Perry E. Bickel;Weiming Xia

Frequent Co-Authors

Dennis J. Selkoe
Dennis J. Selkoe Brigham and Women's Hospital
Rachael L. Neve
Rachael L. Neve Harvard University
Anna M. Krichevsky
Anna M. Krichevsky Brigham and Women's Hospital
Alison Goate
Alison Goate Icahn School of Medicine at Mount Sinai
Alfredo Cáceres
Alfredo Cáceres National Scientific and Technical Research Council
Paul K. Hansma
Paul K. Hansma University of California, Santa Barbara
Adriana Ferreira
Adriana Ferreira Northwestern University
Songi Han
Songi Han University of California, Santa Barbara
Bruce L. Miller
Bruce L. Miller University of California, San Francisco
Eric M. Reiman
Eric M. Reiman Arizona State University

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