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Immunology

D-Index
52
Citations
11561
World Ranking
4043
National Ranking
354

Overview

Kai-Michael Toellner is a researcher affiliated with the University of Birmingham in the United Kingdom. Their work spans the fields of immunology, microbiology, and medicine, with a particular focus on the subfields of immunology, molecular biology, epidemiology, oncology, and endocrine and autonomic systems.

Their research topics concentrate on T-cell and B-cell immunology, immunotherapy and immune responses, immune cell function and interaction, immune response and inflammation, circadian rhythm and melatonin, viral gastroenteritis research and epidemiology, and Salmonella and Campylobacter epidemiology.

Toellner has contributed to various scientific publications, appearing frequently in venues such as bioRxiv (Cold Spring Harbor Laboratory), Science Immunology, The Journal of Experimental Medicine, Cell Reports, and Nature Communications.

Selected recent papers include:

  • Nr4a1 and Nr4a3 Reporter Mice Are Differentially Sensitive to T Cell Receptor Signal Strength and Duration, 2020, Cell Reports
  • Rhythmicity of intestinal IgA responses confers oscillatory commensal microbiota mutualism, 2022, Science Immunology
  • Recycling of memory B cells between germinal center and lymph node subcapsular sinus supports affinity maturation to antigenic drift, 2022, Nature Communications
  • Enhanced BCR signaling inflicts early plasmablast and germinal center B cell death, 2021, iScience
  • IL-21 shapes germinal center polarization via light zone B cell selection and cyclin D3 upregulation, 2023, The Journal of Experimental Medicine

Frequent co-authors who have collaborated with Toellner include Yang Zhang, Lingling Zhang, Juan Carlos Yam-Puc, Laura Garcia-Ibanez, and Adam F. Cunningham. These collaborations have contributed to several publications across multiple respected journals.

Best Publications

  • microRNA-155 Regulates the Generation of Immunoglobulin Class-Switched Plasma Cells

    Elena Vigorito;Kerry L. Perks;Cei Abreu-Goodger;Sam Bunting

  • IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism.

    Dimitra Zotos;Jonathan M. Coquet;Yang Zhang;Amanda Light

  • Extrafollicular antibody responses.

    Ian C. M. MacLennan;Kai-Michael Toellner;Adam F. Cunningham;Karine Serre

  • CD4 T Cell Cytokine Differentiation: The B Cell Activation Molecule, OX40 Ligand, Instructs CD4 T Cells to Express Interleukin 4 and Upregulates Expression of the Chemokine Receptor, Blr-1

    Sarah Flynn;Kai-Michael Toellner;Chandra Raykundalia;Margaret Goodall

  • Class-switch recombination occurs infrequently in germinal centers

    Jonathan A. Roco;Luka Mesin;Sebastian C. Binder;Christian Nefzger

  • Intrinsic constraint on plasmablast growth and extrinsic limits of plasma cell survival

    Daniel M.-Y. Sze;Kai-Michael Toellner;Carola García de Vinuesa;Dale R. Taylor

  • The changing preference of T and B cells for partners as T-dependent antibody responses develop

    I. C. M. Maclennan;A. Gulbranson-Judge;K.-M. Toellner;M. Casamayor-Palleja

  • Germinal center B cells govern their own fate via antibody feedback

    Yang Zhang;Michael Meyer-Hermann;Laura A. George;Marc Thilo Figge

  • T Helper 1 (Th1) and Th2 Characteristics Start to Develop During T Cell Priming and Are Associated with an Immediate Ability to Induce Immunoglobulin Class Switching

    Kai-Michael Toellner;Sanjiv A. Luther;Daniel M.-Y. Sze;Richard K.-W. Choy

  • Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis

    Marieta Caganova;Chiara Carrisi;Gabriele Varano;Federica Mainoldi

  • Morning vaccination enhances antibody response over afternoon vaccination: A cluster-randomised trial

    Joanna E. Long;Mark T. Drayson;Angela E. Taylor;Kai M. Toellner

  • Immunoglobulin switch transcript production in vivo related to the site and time of antigen-specific B cell activation.

    K M Toellner;A Gulbranson-Judge;D R Taylor;D M Sze

  • Salmonella induces a switched antibody response without germinal centers that impedes the extracellular spread of infection.

    Adam F. Cunningham;Fabrina Gaspal;Karine Serre;Elodie Mohr

  • Inflammation-induced formation of fat-associated lymphoid clusters

    Cécile Bénézech;Nguyet-Thin Luu;Jennifer A Walker;Andrei A Kruglov;Andrei A Kruglov;Andrei A Kruglov

  • IL-22 regulates lymphoid chemokine production and assembly of tertiary lymphoid organs.

    Francesca Barone;Francesca Barone;Saba Nayar;Saba Nayar;Joana Campos;Joana Campos;Thomas Cloake;Thomas Cloake

  • Low-level Hypermutation in T Cell–independent Germinal Centers Compared with High Mutation Rates Associated with T Cell–dependent Germinal Centers

    Kai-Michael Toellner;William E. Jenkinson;Dale R. Taylor;Mahmood Khan

  • Cytokine mRNA profiling identifies B cells as a major source of RANKL in rheumatoid arthritis

    Lorraine Yeo;Kai-Michael Toellner;Mike Salmon;Andrew Filer

  • A Theory of Germinal Center B Cell Selection, Division, and Exit

    Michael Meyer-Hermann;Elodie Mohr;Nadége Pelletier;Yang Zhang

  • Regulation of germinal center B-cell differentiation.

    Yang Zhang;Laura Garcia-Ibanez;Kai-Michael Toellner

  • Responses to the soluble flagellar protein FliC are Th2, while those to FliC on Salmonella are Th1

    Adam F. Cunningham;Mahmood Khan;Jennifer Ball;Kai‐Michael Toellner

  • Extrafollicular Antibody Responses

    Carola G. Vinuesa

Frequent Co-Authors

Ian C. M. MacLennan
Ian C. M. MacLennan University of Birmingham
Adam F. Cunningham
Adam F. Cunningham University of Birmingham
Carola G. Vinuesa
Carola G. Vinuesa Australian National University
Hans-Dieter Flad
Hans-Dieter Flad Research Center Borstel - Leibniz-Center for Medicine and Biosciences
Michael Meyer-Hermann
Michael Meyer-Hermann Technische Universität Braunschweig
Sanjiv A. Luther
Sanjiv A. Luther University of Lausanne
Matthew C. Cook
Matthew C. Cook Australian National University
Frank Brombacher
Frank Brombacher University of Cape Town
Johannes Gerdes
Johannes Gerdes Research Center Borstel - Leibniz-Center for Medicine and Biosciences
Ian R. Henderson
Ian R. Henderson University of Cambridge

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