Peter J. L. Lane

Overview

Best Publications

• Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation.

  M Cella;D Scheidegger;K Palmer-Lehmann;P Lane

  3189
  Citations

• Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens.

  Yong-Jun Liu;Jun Zhang;Peter J. L. Lane;Eric Y.-T. Chan

  972
  Citations

• RANK signals from CD4+3− inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla

  Simona W. Rossi;Mi-Yeon Kim;Andreas Leibbrandt;Sonia M. Parnell

  548
  Citations

• CD4 T Cell Cytokine Differentiation: The B Cell Activation Molecule, OX40 Ligand, Instructs CD4 T Cells to Express Interleukin 4 and Upregulates Expression of the Chemokine Receptor, Blr-1

  Sarah Flynn;Kai-Michael Toellner;Chandra Raykundalia;Margaret Goodall

  537
  Citations

• Activated human T cells express a ligand for the human B cell‐associated antigen CD40 which participates in T cell‐dependent activation of B lymphocytes

  Peter Lane;André Traunecker;Sabine Hubele;Seiji Inui

  518
  Citations

• Compromised Ox40 Function in Cd28-Deficient Mice Is Linked with Failure to Develop Cxc Chemokine Receptor 5–Positive Cd4 Cells and Germinal Centers

  Lucy S.K. Walker;Adam Gulbranson-Judge;Sarah Flynn;Thomas Brocker

  412
  Citations

• CD4(+)CD3(-) accessory cells costimulate primed CD4 T cells through OX40 and CD30 at sites where T cells collaborate with B cells.

  Mi-Yeon Kim;Fabrina M.C Gaspal;Helen E Wiggett;Fiona M McConnell

  344
  Citations

• Clinical, immunologic and genetic analysis of 29 patients with autosomal recessive hyper-IgM syndrome due to Activation-Induced Cytidine Deaminase deficiency

  Pierre Quartier;Jacinta Bustamante;Ozden Sanal;Alessandro Plebani

  316
  Citations

• CD23: a multi-functional receptor/ lymphokine?

  J. Gordon;L. Flores-Romo;J.A. Caims;M.J. Millsum

  292
  Citations

• OX40, OX40L and Autoimmunity: a Comprehensive Review

  Gwilym J. Webb;Gwilym J. Webb;Gideon M. Hirschfield;Peter J. L. Lane

  292
  Citations

• CD4 T cell traffic control: in vivo evidence that ligation of OX40 on CD4 T cells by OX40-ligand expressed on dendritic cells leads to the accumulation of CD4 T cells in B follicles.

  Thomas Brocker;Adam Gulbranson-Judge;Sarah Flynn;Mireille Riedinger

  290
  Citations

• Generating intrathymic microenvironments to establish T-cell tolerance

  Graham Anderson;Peter J. L. Lane;Eric J. Jenkinson

  245
  Citations

• The Evolution of B-Cell Clones

  I. C. M. MacLennan;Y. J. Liu;S. Oldfield;J. Zhang

  245
  Citations

• Salmonella induces a switched antibody response without germinal centers that impedes the extracellular spread of infection.

  Adam F. Cunningham;Fabrina Gaspal;Karine Serre;Elodie Mohr

  243
  Citations

• The thymic medulla is required for Foxp3+ regulatory but not conventional CD4+ thymocyte development.

  Jennifer E. Cowan;Sonia M. Parnell;Kyoko Nakamura;Jorge H. Caamano

  218
  Citations

• Role of Ox40 Signals in Coordinating Cd4 T Cell Selection, Migration, and Cytokine Differentiation in T Helper (Th)1 and Th2 Cells

  Peter Lane

  209
  Citations

• Mice Deficient in OX40 and CD30 Signals Lack Memory Antibody Responses because of Deficient CD4 T Cell Memory

  Fabrina M. C. Gaspal;Mi-Yeon Kim;Fiona M. McConnell;Chandra Raykundalia

  208
  Citations

• Rank Signaling Links the Development of Invariant γδ T Cell Progenitors and Aire+ Medullary Epithelium

  Natalie A. Roberts;Andrea J. White;William E. Jenkinson;Gleb Turchinovich;Gleb Turchinovich

  188
  Citations

• Is rapid proliferation in B centroblasts linked to somatic mutation in memory B cell clones

  Jun Zhang;Ian C.M. MacLennan;Yong-Jun Liu;Peter J.L. Lane

  183
  Citations

• Generation of both cortical and Aire+ medullary thymic epithelial compartments from CD205+ progenitors

  Song Baik;Eric J. Jenkinson;Peter J. L. Lane;Graham Anderson

  167
  Citations