2026 Lucy S. K. Walker: Immunology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Immunology	53	3936	3630	345	334	107	15559

Overview

Lucy S. K. Walker is affiliated with University College London in the United Kingdom and has contributed extensively to the fields of immunology and medicine, with a particular emphasis on immunology and microbiology. Their research portfolio includes significant work spanning subfields such as immunology, oncology, genetics, surgery, and epidemiology.

Their scholarly output is concentrated on several main topics, which include:

Immune Cell Function and Interaction
T-cell and B-cell Immunology
Immunotherapy and Immune Responses
Diabetes and associated disorders
Cancer Immunotherapy and Biomarkers
Diabetes Management and Research
Pancreatic function and diabetes

Walker's recent publications illustrate a focus on immune regulation and autoimmune diseases. Notable papers include:

"Targeting co-stimulatory molecules in autoimmune disease," 2020, published in Nature Reviews Drug Discovery
"Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation," 2022, in Nature Immunology
"Type 1 diabetes," 2023, in The Lancet
"The link between circulating follicular helper T cells and autoimmunity," 2022, in Nature reviews. Immunology
"The immunology of type 1 diabetes," 2024, in Nature reviews. Immunology

Frequent co-authors with whom Walker has collaborated include:

Natalie M. Edner
Chun Jing Wang
Lina Petersone
Frank Heuts
Ellen M. Ross

Walker has published frequently in several leading scientific venues. These include:

Nature Immunology
Nature Communications
Immunotherapy Advances
Nature Reviews Drug Discovery
Nature reviews. Immunology

The scientist's work demonstrates an ongoing engagement with both fundamental and applied aspects of immune cell function, with a particular focus on T-cell and B-cell immunology and autoimmune conditions such as type 1 diabetes. Their research is positioned at the intersection of immunotherapy, immune regulation, and disease management, contributing to the understanding of immune responses in complex diseases.

Best Publications

Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell-Extrinsic Function of CTLA-4

Omar S. Qureshi;Yong Zheng;Kyoko Nakamura;Kesley Attridge

2159
Citations
The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses

Lucy S. K. Walker;David M. Sansom

972
Citations
1,25-Dihydroxyvitamin D3 and IL-2 Combine to Inhibit T Cell Production of Inflammatory Cytokines and Promote Development of Regulatory T Cells Expressing CTLA-4 and FoxP3

Louisa E. Jeffery;Fiona Burke;Manuela Mura;Yong Zheng

956
Citations
Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations.

Desireé Schubert;Desireé Schubert;Claudia Bode;Rupert Kenefeck;Tie Zheng Hou

894
Citations
The enemy within: keeping self-reactive T cells at bay in the periphery

Lucy S.K. Walker;Abul K. Abbas

813
Citations
Antigen-dependent Proliferation of CD4+ CD25+ Regulatory T Cells In Vivo

Lucy S.K. Walker;Anna Chodos;Mark Eggena;Hans Dooms

747
Citations
Treg and CTLA-4: two intertwining pathways to immune tolerance.

Lucy S.K. Walker

486
Citations
Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties.

Eva Billerbeck;Yu Hoi Kang;Lucy Walker;Helen Lockstone

427
Citations
Confusing signals: Recent progress in CTLA-4 biology

Lucy S.K. Walker;David M. Sansom

427
Citations
The role of CD28 and cytotoxic T‐lymphocyte antigen‐4 (CTLA‐4) in regulatory T‐cell biology

David M. Sansom;Lucy S. K. Walker

414
Citations
Compromised Ox40 Function in Cd28-Deficient Mice Is Linked with Failure to Develop Cxc Chemokine Receptor 5–Positive Cd4 Cells and Germinal Centers

Lucy S.K. Walker;Adam Gulbranson-Judge;Sarah Flynn;Thomas Brocker

412
Citations
CTLA4 gene polymorphism and autoimmunity

Stephen C. L. Gough;Lucy S. K. Walker;David M. Sansom

387
Citations
Cutting edge: The phosphoinositide 3-kinase p110 delta is critical for the function of CD4(+)CD25(+)Foxp3(+) regulatory T cells

Daniel T. Patton;Oliver A. Garden;Oliver A. Garden;Wayne P. Pearce;Louise E. Clough

363
Citations
CD4(+)CD3(-) accessory cells costimulate primed CD4 T cells through OX40 and CD30 at sites where T cells collaborate with B cells.

Mi-Yeon Kim;Fabrina M.C Gaspal;Helen E Wiggett;Fiona M McConnell

344
Citations
Distinct Roles for CCR4 and CXCR3 in the Recruitment and Positioning of Regulatory T Cells in the Inflamed Human Liver

Ye H. Oo;Chris J. Weston;Patricia F. Lalor;Stuart M. Curbishley

266
Citations
Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation

Unknown

244
Citations
CTLA-4 controls follicular helper T-cell differentiation by regulating the strength of CD28 engagement

Chun Jing Wang;Frank Heuts;Vitalijs Ovcinnikovs;Lukasz Wardzinski

215
Citations
Epithelial inflammation is associated with CCL28 production and the recruitment of regulatory T cells expressing CCR10.

Bertus Eksteen;Alice Miles;Stuart M. Curbishley;Chris Tselepis

213
Citations
CD4 T cell differentiation in type 1 diabetes

L S K Walker;M von Herrath

212
Citations
Targeting co-stimulatory molecules in autoimmune disease

Natalie M. Edner;Gianluca Carlesso;James S. Rush;Lucy S. K. Walker

209
Citations
Ctla-4 controls regulatory T cell peripheral homeostasis and is required for suppression of pancreatic islet autoimmunity.

Emily M. Schmidt;Chun Jing Wang;Gemma A. Ryan;Louise E. Clough

187
Citations
Follicular helper T cell signature in type 1 diabetes

Rupert Kenefeck;Chun Jing Wang;Tauseef Kapadi;Lukasz Wardzinski

179
Citations

Frequent Co-Authors

David M. Sansom University College London

Abul K. Abbas University of California, San Francisco

Peter J. L. Lane University of Birmingham

Siobhan O. Burns University College London

Graham Anderson University of Birmingham

Klaus Okkenhaug University of Cambridge

Hans J. Stauss University College London

Bart Vanhaesebroeck University College London

Alan D. Salama University College London

Jorge Caamano University of Birmingham

External Links

Personal website of Lucy S. K. Walker

If you think any of the details on this page are incorrect, let us know.

Related Online Degrees & Career Pathways

Pursuing an education in Immunology opens the door to various advanced healthcare roles, including specialties in nursing and practitioner fields. For those interested in psychiatric care, exploring the best pmhnp programs can provide valuable clinical experience and strong job placement rates.

Cost is another crucial factor when selecting a program. Many professionals look for the cheapest psychiatric nurse practitioner programs that still maintain high standards of education and clinical practice.

Financial considerations extend beyond tuition—understanding how much do dnps make across different states can help graduates plan their careers effectively, balancing salary expectations with location preferences and cost of living.

For those already practicing as Family Nurse Practitioners, transitioning to more specialized fields is common. The guide on fnp to acute care np offers insights into shifting focus towards acute care settings, expanding career opportunities within healthcare.