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Genetics

D-Index
84
Citations
54146
World Ranking
1333
National Ranking
632

Overview

Narisu Narisu is a researcher affiliated with the National Institutes of Health in the United States, with a primary focus on Biochemistry, Genetics, and Molecular Biology as well as Medicine. Their scholarly output spans multiple subfields including Molecular Biology, Surgery, Genetics, Cancer Research, and Physiology.

Their research engages extensively with topics related to pancreatic function and diabetes, genetic associations and epidemiology, diabetes and associated disorders, CRISPR and genetic engineering, congenital heart defects research, microRNA in disease regulation, and single-cell and spatial transcriptomics.

The following recent papers illustrate the scope and focus of their research work:

  • In vivo base editing rescues Hutchinson-Gilford progeria syndrome in mice, 2021, Nature
  • SARS-CoV-2 infection induces beta cell transdifferentiation, 2021, Cell Metabolism
  • Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D, 2020, Nature Communications
  • A targeted antisense therapeutic approach for Hutchinson-Gilford progeria syndrome, 2021, Nature Medicine
  • Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake, 2023, Nature Genetics

Narisu Narisu frequently collaborates with several notable co-authors, including:

  • Michael R. Erdos
  • Francis S. Collins
  • Lori L. Bonnycastle
  • Tingfen Yan
  • Stephen C.J. Parker

Their works have been published predominantly in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Diabetes
  • Zenodo (CERN European Organization for Nuclear Research)
  • Nature Genetics

This combination of research topics, collaborative networks, and publication venues underscores a focused interest in understanding molecular mechanisms underlying metabolic diseases and genetic disorders, with particular attention to innovative approaches in gene editing and functional genomics applied to diabetes and progeria.

Best Publications

  • Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

    Elizabeth K. Speliotes;Elizabeth K. Speliotes;Cristen J. Willer;Sonja I. Berndt;Keri L. Monda

  • A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.

    Laura J. Scott;Karen L. Mohlke;Lori L. Bonnycastle;Cristen J. Willer

  • Discovery and refinement of loci associated with lipid levels

    Cristen J. Willer;Ellen M. Schmidt;Sebanti Sengupta;Gina M. Peloso;Gina M. Peloso;Gina M. Peloso

  • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

    Josée Dupuis;Josée Dupuis;Claudia Langenberg;Inga Prokopenko;Richa Saxena;Richa Saxena

  • Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

    Georg B. Ehret;Georg B. Ehret;Georg B. Ehret;Patricia B. Munroe;Kenneth M. Rice;Murielle Bochud

  • Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

    E Zeggini;L J Scott;R Saxena;B F Voight

  • Defining the role of common variation in the genomic and biological architecture of adult human height

    Andrew R. Wood;Tonu Esko;Jian Yang;Sailaja Vedantam

  • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (vol 42, pg 105, 2010)

    J Dupuis;C Langenberg;I Prokopenko;R Saxena

  • Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

    Benjamin F. Voight;Benjamin F. Voight;Laura J. Scott;Valgerdur Steinthorsdottir;Andrew P. Morris

  • Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

    Cristen J. Willer;Elizabeth K. Speliotes;Elizabeth K. Speliotes;Ruth J. F. Loos;Shengxu Li

  • Newly identified loci that influence lipid concentrations and risk of coronary artery disease

    Cristen J. Willer;Serena Sanna;Anne U. Jackson;Angelo Scuteri

  • A genome-wide association search for type 2 diabetes genes in African Americans.

    N D Palmer;C W McDonough;P J Hicks;B H Roh

  • The genetic architecture of type 2 diabetes

    Christian Fuchsberger;Christian Fuchsberger;Jason A. Flannick;Jason A. Flannick;Tanya M. Teslovich;Anubha Mahajan

  • Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

    E. K. Speliotes;C. J. Willer;S. I. Berndt;K. L. Monda

  • Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

    Iris M. Heid;Anne U. Jackson;Joshua C. Randall;Tthomas W. Winkler

  • Common variants associated with plasma triglycerides and risk for coronary artery disease

    Ron Do;Cristen J. Willer;Ellen M. Schmidt;Sebanti Sengupta

  • A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.

    Alisa K. Manning;Alisa K. Manning;Alisa K. Manning;Robert A. Scott;Jonna L. Grimsby

  • Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

    Richa Saxena;Richa Saxena;Claudia Langenberg;Toshiko Tanaka;Toshiko Tanaka

  • Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (Nature Genetics (2010) 42 (105-116))

    Josée Dupuis;Claudia Langenberg;Inga Prokopenko;Richa Saxena

  • The genetic architecture of type 2 diabetes

    Christian Fuchsberger;Jason Flannick;Tanya M. Teslovich;Anubha Mahajan

Frequent Co-Authors

Francis S. Collins
Francis S. Collins National Institutes of Health
Michael Boehnke
Michael Boehnke University of Michigan–Ann Arbor
Jaakko Tuomilehto
Jaakko Tuomilehto University of Helsinki
Anne U. Jackson
Anne U. Jackson University of Michigan–Ann Arbor
Markku Laakso
Markku Laakso University of Eastern Finland
Inês Barroso
Inês Barroso University of Exeter
Karen L. Mohlke
Karen L. Mohlke University of North Carolina at Chapel Hill
Lori L. Bonnycastle
Lori L. Bonnycastle National Institutes of Health
Johanna Kuusisto
Johanna Kuusisto University of Eastern Finland

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