World's Best Scientists 2026 revealed!
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Best Female Scientists
2025
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Genetics
USA
2026

D-Index & Metrics

Best Female Scientists

D-Index
135
Citations
118512
World Ranking
275
National Ranking
173

Genetics

D-Index
138
Citations
118153
World Ranking
194
National Ranking
102

Medicine

D-Index
138
Citations
118911
World Ranking
1789
National Ranking
1023

Research.com Recognitions

  • 2026 - Research.com Genetics in United States Leader Award
  • 2025 - Research.com Best Female Scientists Award
  • 2014 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Karen L. Mohlke is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research spans various topics within biochemistry, genetics, molecular biology, and medicine, reflecting expertise in both broad and specialized subfields. The scientist's work includes contributions to molecular biology, genetics, surgery, epidemiology, and cancer research.

The main research topics addressed by Karen L. Mohlke include:

  • Genetic Associations and Epidemiology
  • Epigenetics and DNA Methylation
  • Pancreatic Function and Diabetes
  • Cancer-related Molecular Mechanisms Research
  • Adipose Tissue and Metabolism
  • Nutrition, Genetics, and Disease
  • Bioinformatics and Genomic Networks

Some of the recent publications represent significant work in genetics and blood traits, disease-relevant loci, and gene expression related to diabetes. Notable papers include:

  • "The Polygenic and Monogenic Basis of Blood Traits and Diseases," 2020, published in Cell
  • "Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations," 2020, published in Cell
  • "Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci," 2022, published in Nature Communications
  • "Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D," 2020, published in Nature Communications
  • "Content and Performance of the MiniMUGA Genotyping Array: A New Tool To Improve Rigor and Reproducibility in Mouse Research," 2020, published in Genetics

Karen L. Mohlke has collaborated frequently with several other researchers. Key co-authors include:

  • Michael Boehnke
  • Swarooparani Vadlamudi
  • Markku Laakso
  • Stephen C.J. Parker
  • Francis S. Collins

The scientist's works have appeared predominantly in specific venues, reflecting a focus on genetics and biomedical sciences. Major publication venues include:

  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • Nature Communications
  • The American Journal of Human Genetics

Karen L. Mohlke has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS) since 2014.

Best Publications

  • Biological, clinical and population relevance of 95 loci for blood lipids

    Tanya M. Teslovich;Kiran Musunuru;Albert V. Smith;Andrew C. Edmondson

  • Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

    Elizabeth K. Speliotes;Elizabeth K. Speliotes;Cristen J. Willer;Sonja I. Berndt;Keri L. Monda

  • A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.

    Laura J. Scott;Karen L. Mohlke;Lori L. Bonnycastle;Cristen J. Willer

  • A reference panel of 64,976 haplotypes for genotype imputation

    Shane McCarthy;Sayantan Das;Warren Kretzschmar;Olivier Delaneau

  • Discovery and refinement of loci associated with lipid levels

    Cristen J. Willer;Ellen M. Schmidt;Sebanti Sengupta;Gina M. Peloso;Gina M. Peloso;Gina M. Peloso

  • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

    Josée Dupuis;Josée Dupuis;Claudia Langenberg;Inga Prokopenko;Richa Saxena;Richa Saxena

  • Plasma HDL cholesterol and risk of myocardial infarction: A mendelian randomisation study

    Benjamin F. Voight;Benjamin F. Voight;Benjamin F. Voight;Gina M. Peloso;Gina M. Peloso;Marju Orho-Melander;Ruth Frikke-Schmidt

  • Hundreds of variants clustered in genomic loci and biological pathways affect human height

    Hana Lango Allen;Karol Estrada;Guillaume Lettre;Sonja I. Berndt

  • Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

    Georg B. Ehret;Georg B. Ehret;Georg B. Ehret;Patricia B. Munroe;Kenneth M. Rice;Murielle Bochud

  • Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

    E Zeggini;L J Scott;R Saxena;B F Voight

  • Defining the role of common variation in the genomic and biological architecture of adult human height

    Andrew R. Wood;Tonu Esko;Jian Yang;Sailaja Vedantam

  • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (vol 42, pg 105, 2010)

    J Dupuis;C Langenberg;I Prokopenko;R Saxena

  • Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

    Benjamin F. Voight;Benjamin F. Voight;Laura J. Scott;Valgerdur Steinthorsdottir;Andrew P. Morris

  • Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

    Andrew P Morris;Benjamin F Voight;Benjamin F Voight;Tanya M Teslovich;Teresa Ferreira

  • Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

    Cristen J. Willer;Elizabeth K. Speliotes;Elizabeth K. Speliotes;Ruth J. F. Loos;Shengxu Li

  • Newly identified loci that influence lipid concentrations and risk of coronary artery disease

    Cristen J. Willer;Serena Sanna;Anne U. Jackson;Angelo Scuteri

  • A genome-wide association search for type 2 diabetes genes in African Americans.

    N D Palmer;C W McDonough;P J Hicks;B H Roh

  • Genetic studies of body mass index yield new insights for obesity biology

    Adam E. Locke;Bratati Kahali;Sonja I. Berndt;Anne E. Justice

  • Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (Nature Genetics (2010) 42 (105-116))

    Josée Dupuis;Claudia Langenberg;Inga Prokopenko;Richa Saxena

  • Hundreds of variants clustered in genomic loci and biological pathways affect human height

    H. Lango Allen;K. Estrada;G. Lettre;S. I. Berndt

Frequent Co-Authors

Michael Boehnke
Michael Boehnke University of Michigan–Ann Arbor
Jaakko Tuomilehto
Jaakko Tuomilehto University of Helsinki
Francis S. Collins
Francis S. Collins National Institutes of Health
Anne U. Jackson
Anne U. Jackson University of Michigan–Ann Arbor
Johanna Kuusisto
Johanna Kuusisto University of Eastern Finland
Nicholas J. Wareham
Nicholas J. Wareham University of Cambridge
Cecilia M. Lindgren
Cecilia M. Lindgren University of Oxford
Philippe Froguel
Philippe Froguel Imperial College London
Leif Groop
Leif Groop Lund University

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