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Genetics

D-Index
96
Citations
76466
World Ranking
850
National Ranking
429

Overview

Lori L. Bonnycastle is affiliated with the National Institutes of Health in the United States. Their research spans multiple facets of biochemistry, genetics, and molecular biology, with significant contributions also in medicine. The scientist's work is categorized primarily under the fields of Biochemistry, Genetics and Molecular Biology and Medicine, with subfields including Genetics, Molecular Biology, Surgery, Cancer Research, and Physiology.

The topics most frequently addressed in their research include:

  • Genetic Associations and Epidemiology
  • Pancreatic function and diabetes
  • Genomics and Rare Diseases
  • Bioinformatics and Genomic Networks
  • Epigenetics and DNA Methylation
  • CRISPR and Genetic Engineering
  • Congenital heart defects research

Lori L. Bonnycastle has co-authored numerous publications with several frequent collaborators, including:

  • Michael R. Erdos, with 44 joint publications
  • Narisu Narisu, with 41 joint publications
  • Francis S. Collins, with 39 joint publications
  • Anne Jackson, with 34 joint publications
  • Michael Boehnke, with 31 joint publications

The scientist's research has appeared extensively in certain publication venues. The most common venues for their publications include:

  • UNC Libraries, featuring 29 publications
  • bioRxiv (Cold Spring Harbor Laboratory), with 14 publications
  • Nature, with 7 publications
  • Nature Communications, also with 7 publications
  • Nature Genetics, with 6 publications

Some of the recent papers authored or co-authored by Lori L. Bonnycastle demonstrate a focus on human genetic variation and its implications. Notable examples include:

  • "The mutational constraint spectrum quantified from variation in 141,456 humans," published in 2020 in Nature
  • "A structural variation reference for medical and population genetics," published in 2020 in Nature
  • "A genomic mutational constraint map using variation in 76,156 human genomes," published in 2023 in Nature
  • "A saturated map of common genetic variants associated with human height," published in 2022 in Nature
  • "Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals," published in 2020 in Nature Genetics

Best Publications

  • Biological, clinical and population relevance of 95 loci for blood lipids

    Tanya M. Teslovich;Kiran Musunuru;Albert V. Smith;Andrew C. Edmondson

  • Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

    Elizabeth K. Speliotes;Elizabeth K. Speliotes;Cristen J. Willer;Sonja I. Berndt;Keri L. Monda

  • A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.

    Laura J. Scott;Karen L. Mohlke;Lori L. Bonnycastle;Cristen J. Willer

  • Discovery and refinement of loci associated with lipid levels

    Cristen J. Willer;Ellen M. Schmidt;Sebanti Sengupta;Gina M. Peloso;Gina M. Peloso;Gina M. Peloso

  • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

    Josée Dupuis;Josée Dupuis;Claudia Langenberg;Inga Prokopenko;Richa Saxena;Richa Saxena

  • Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

    Georg B. Ehret;Georg B. Ehret;Georg B. Ehret;Patricia B. Munroe;Kenneth M. Rice;Murielle Bochud

  • Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

    E Zeggini;L J Scott;R Saxena;B F Voight

  • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (vol 42, pg 105, 2010)

    J Dupuis;C Langenberg;I Prokopenko;R Saxena

  • Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

    Benjamin F. Voight;Benjamin F. Voight;Laura J. Scott;Valgerdur Steinthorsdottir;Andrew P. Morris

  • Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

    Andrew P Morris;Benjamin F Voight;Benjamin F Voight;Tanya M Teslovich;Teresa Ferreira

  • Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

    Cristen J. Willer;Elizabeth K. Speliotes;Elizabeth K. Speliotes;Ruth J. F. Loos;Shengxu Li

  • Newly identified loci that influence lipid concentrations and risk of coronary artery disease

    Cristen J. Willer;Serena Sanna;Anne U. Jackson;Angelo Scuteri

  • A genome-wide association search for type 2 diabetes genes in African Americans.

    N D Palmer;C W McDonough;P J Hicks;B H Roh

  • Genetic studies of body mass index yield new insights for obesity biology

    Adam E. Locke;Bratati Kahali;Sonja I. Berndt;Anne E. Justice

  • Common variants at 30 loci contribute to polygenic dyslipidemia.

    Sekar Kathiresan;Sekar Kathiresan;Sekar Kathiresan;Cristen J. Willer;Gina M. Peloso;Serkalem Demissie

  • Genome-wide association study identifies eight loci associated with blood pressure

    Christopher Newton-Cheh;Christopher Newton-Cheh;Toby Johnson;Toby Johnson;Vesela Gateva;Martin D. Tobin

  • The genetic architecture of type 2 diabetes

    Christian Fuchsberger;Christian Fuchsberger;Jason A. Flannick;Jason A. Flannick;Tanya M. Teslovich;Anubha Mahajan

  • Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

    E. K. Speliotes;C. J. Willer;S. I. Berndt;K. L. Monda

  • Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

    Iris M. Heid;Anne U. Jackson;Joshua C. Randall;Tthomas W. Winkler

  • Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (Nature Genetics (2010) 42 (105-116))

    Josée Dupuis;Claudia Langenberg;Inga Prokopenko;Richa Saxena

Frequent Co-Authors

Jaakko Tuomilehto
Jaakko Tuomilehto University of Helsinki
Michael Boehnke
Michael Boehnke University of Michigan–Ann Arbor
Francis S. Collins
Francis S. Collins National Institutes of Health
Anne U. Jackson
Anne U. Jackson University of Michigan–Ann Arbor
Leif Groop
Leif Groop Lund University
Inês Barroso
Inês Barroso University of Exeter
Karen L. Mohlke
Karen L. Mohlke University of North Carolina at Chapel Hill
Johanna Kuusisto
Johanna Kuusisto University of Eastern Finland
Philippe Froguel
Philippe Froguel Imperial College London

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