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Immunology

D-Index
81
Citations
26334
World Ranking
1552
National Ranking
775

Research.com Recognitions

  • 2019 - Distinguished Fellows of the American Association of Immunologists (AAI)
  • 1997 - AAI Distinguished Service Award, American Association of Immunologists For his contributions as AAI Education Committee Chair, 1994-1996

Overview

Stephen M. Hedrick is affiliated with the University of California, San Diego in the United States. Their research spans the fields of immunology, microbiology, biochemistry, genetics, and molecular biology, with a focus on subfields such as immunology, molecular biology, radiation, plant science, and oncology.

The main topics of their scientific work include immune cell function and interaction, T-cell and B-cell immunology, CRISPR and genetic engineering, chromosomal and genetic variations, immunotherapy and immune responses, FOXO transcription factor regulation, and single-cell and spatial transcriptomics.

Recent papers published by Stephen M. Hedrick include:

  • Delineation of a molecularly distinct terminally differentiated memory CD8 T cell population, 2020, Proceedings of the National Academy of Sciences
  • FOXO1 constrains activation and regulates senescence in CD8 T cells, 2021, Cell Reports
  • Meiotic Cas9 expression mediates gene conversion in the male and female mouse germline, 2021, PLoS Biology
  • Transcriptomes and metabolism define mouse and human MAIT cell populations, 2023, Science Immunology
  • Bromodomain protein BRD4 directs and sustains CD8 T cell differentiation during infection, 2021, The Journal of Experimental Medicine

Stephen M. Hedrick has frequently collaborated with researchers including Nimi Marcel, Arnaud Delpoux, Li-Fan Lu, J. Justin Milner, and Hongtuyet Nguyen.

The venues where they have published extensively include the International Journal of Particle Therapy, bioRxiv (Cold Spring Harbor Laboratory), The Journal of Immunology, Science Immunology, and Current Opinion in Immunology.

Awards received by Stephen M. Hedrick are the Distinguished Fellows of the American Association of Immunologists (AAI) in 2019 and the AAI Distinguished Service Award in 1997 for contributions as AAI Education Committee Chair from 1994 to 1996.

Best Publications

  • Identification of RIP1 kinase as a specific cellular target of necrostatins.

    Alexei Degterev;Junichi Hitomi;Megan Germscheid;Irene L Ch'en

  • Isolation of cDNA clones encoding T cell-specific membrane-associated proteins.

    Stephen M. Hedrick;Stephen M. Hedrick;David I. Cohen;David I. Cohen;Ellen A. Nielsen;Mark M. Davis;Mark M. Davis

  • Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis

    Claudia Günther;Eva Martini;Nadine Wittkopf;Kerstin Amann

  • Sequence relationships between putative T-cell receptor polypeptides and immunoglobulins

    Stephen M. Hedrick;Stephen M. Hedrick;Ellen A. Nielsen;Joshua Kavaler;David I. Cohen;David I. Cohen

  • Selective development of CD4 + T cells in transgenic mice expressing a class II MHC-restricted antigen receptor

    Jonathan Kaye;Mei Ling Hsu;Marie Elizabeth Sauron;Stephen C. Jameson

  • MAPK3/1 (ERK1/2) in Ovarian Granulosa Cells Are Essential for Female Fertility

    Heng-Yu Fan;Zhilin Liu;Masayuki Shimada;Esta Sterneck

  • Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor

    Yann M Kerdiles;Daniel R Beisner;Roberto Tinoco;Anne S Dejean

  • Combinatorial Roles of the Nuclear Receptor Corepressor in Transcription and Development

    Kristen Jepsen;Ola Hermanson;Thandi M Onami;Anatoli S Gleiberman

  • Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs

    Jie Jiang;Jie Jiang;Qiang Zhu;Tania F. Gendron;Shahram Saberi

  • Helper T-cell subsets: phenotype, function and the role of lymphokines in regulating their development.

    Susan L. Swain;Linda M. Bradley;Michael Croft;Susan Tonkonogy

  • Foxo Transcription Factors Control Regulatory T Cell Development and Function

    Yann M. Kerdiles;Erica L. Stone;Daniel L. Beisner;Maureen A. McGargill

  • The CD95 receptor: apoptosis revisited.

    Marcus E. Peter;Ralph C. Budd;Julie Desbarats;Stephen M. Hedrick

  • Correlations between T-cell specificity and the structure of the antigen receptor.

    Pamela J. Fink;Louis A. Matis;David L. McElligott;Michael Bookman

  • The Role of Erk1 and Erk2 in Multiple Stages of T Cell Development

    April M. Fischer;Carol D. Katayama;Giles Pagès;Jacques Pouysségur

  • FOXO transcription factors throughout T cell biology

    Stephen M. Hedrick;Rodrigo Hess Michelini;Andrew L. Doedens;Ananda W. Goldrath

  • A semisynthetic epitope for kinase substrates.

    Jasmina J. Allen;Manqing Li;Craig S. Brinkworth;Jennifer L. Paulson;Jennifer L. Paulson

  • Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade

    Gretchen Bain;Celia B. Cravatt;Cindy Loomans;Jose Alberola-Ila

  • Schlafen, a New Family of Growth Regulatory Genes that Affect Thymocyte Development

    David A Schwarz;Carol D Katayama;Stephen M Hedrick

  • Transcription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells

    Anne S Dejean;Daniel R Beisner;Daniel R Beisner;Irene L Ch'en;Yann M Kerdiles

  • MHC Class II–Specific T Cells Can Develop in the CD8 Lineage When CD4 Is Absent

    Errin O Matechak;Nigel Killeen;Stephen M Hedrick;B.J Fowlkes

  • A Role for FADD in T Cell Activation and Development

    Craig M Walsh;Ben G Wen;Arul M Chinnaiyan;Karen O'Rourke

  • Bcl-2 is upregulated at the CD4^+ CD8^+ stage during positive selection and promotes thymocyte differentiation at several control points

    Gerald P. Linette;Michael J. Grusby;Stephen M. Hedrick;Ted H. Hansen

Frequent Co-Authors

Mark M. Davis
Mark M. Davis Stanford University
Louis A. Matis
Louis A. Matis Alexion Pharma (Switzerland)
Eric A. Stone
Eric A. Stone North Carolina State University
Jeffrey A. Bluestone
Jeffrey A. Bluestone University of California, San Francisco
Ananda W. Goldrath
Ananda W. Goldrath University of California, San Diego
Ronald H. Schwartz
Ronald H. Schwartz National Institutes of Health
Lawrence P. Kane
Lawrence P. Kane University of Pittsburgh
Nicholas R. J. Gascoigne
Nicholas R. J. Gascoigne National University of Singapore
Tatsuro Irimura
Tatsuro Irimura Juntendo University
Diego H. Castrillon
Diego H. Castrillon The University of Texas Southwestern Medical Center

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