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Tatsuro Irimura

Tatsuro Irimura

D-Index & Metrics

Biology and Biochemistry

D-Index
74
Citations
17553
World Ranking
5667
National Ranking
366

Overview

Tatsuro Irimura is affiliated with Juntendo University in Japan. Their scientific research spans several main fields including Biochemistry, Genetics and Molecular Biology, Immunology and Microbiology, and Medicine. Their work focuses particularly on molecular and cellular processes associated with glycosylation, immune function, and cancer biology.

The scientist has contributed extensively to the study of glycosylation and glycoproteins, having 28 publications covering this topic. Other prominent research areas include monoclonal and polyclonal antibodies, galectins related to cancer biology, proteoglycans and glycosaminoglycans, as well as immunotherapy and immune responses.

They have collaborated frequently with several researchers, including Kaori Denda-Nagai (13 joint publications), Miki Noji (7), Katrin Ishii-Schrade (6), Haruhiko Fujihira (6), and Yoshiya Horimoto (5).

Tatsuro Irimura's publications are commonly found in venues such as the International Journal of Molecular Sciences, which features five of their papers. Other publication venues include PLoS ONE (2 papers), Advances in experimental medicine and biology, Journal of Experimental & Clinical Cancer Research, and Cell Death Discovery.

Among their recent papers are:

  • Heparanase is Involved in Leukocyte Migration, 2020, Advances in experimental medicine and biology
  • Mucin 21 confers resistance to apoptosis in an O-glycosylation-dependent manner, 2022, Cell Death Discovery
  • A CRISPR activation screen identifies MUC-21 as critical for resistance to NK and T cell-mediated cytotoxicity, 2023, Journal of Experimental & Clinical Cancer Research
  • A Possible Inhibitory Role of Sialic Acid on MUC1 in Peritoneal Dissemination of Clear Cell-Type Ovarian Cancer Cells, 2021, Molecules
  • Glycans unique to the relapse-prone subset within triple-negative breast cancer as revealed by lectin array-based analysis of surgical specimens, 2021, PLoS ONE

Their subfields of study include Molecular Biology, Immunology, Radiology, Nuclear Medicine and Imaging, Cell Biology, and Immunology and Allergy. This indicates a multidisciplinary approach that encompasses both fundamental biochemical mechanisms and applied medical research topics.

Best Publications

  • Increased Expression of Sialyl Lewisx Antigen Correlates with Poor Survival in Patients with Colorectal Carcinoma: Clinicopathological and Immunohistochemical Study

    Shoji Nakamori;Masao Kameyama;Shingi Imaoka;Hiroshi Furukawa

  • Overproduction of Th2-specific chemokines in NC/Nga mice exhibiting atopic dermatitis–like lesions

    Christian Vestergaard;Hiroyuki Yoneyama;Masako Murai;Kohichiro Nakamura

  • Direct evidence of nitric oxide production from bovine aortic endothelial cells using new fluorescence indicators: diaminofluoresceins

    Naoki Nakatsubo;Hirotatsu Kojima;Kazuya Kikuchi;Hiroshi Nagoshi

  • Heparanases and tumor metastasis.

    Motowo Nakajima;Tatsuro Irimura;Garth L. Nicolson

  • Metastatic melanoma cell heparanase. Characterization of heparan sulfate degradation fragments produced by B16 melanoma endoglucuronidase.

    M Nakajima;T Irimura;N Di Ferrante;G L Nicolson

  • Tyro3 Family-Mediated Cell Entry of Ebola and Marburg Viruses

    Masayuki Shimojima;Ayato Takada;Hideki Ebihara;Hideki Ebihara;Gabriele Neumann

  • Human Macrophage C-Type Lectin Specific for Galactose and N-Acetylgalactosamine Promotes Filovirus Entry

    Ayato Takada;Kouki Fujioka;Makoto Tsuiji;Akiko Morikawa

  • Carbohydrate profiling reveals a distinctive role for the C-type lectin MGL in the recognition of helminth parasites and tumor antigens by dendritic cells

    Sandra J. van Vliet;Ellis van Liempt;Eirikur Saeland;Corlien A. Aarnoudse

  • Antitumor activity of small interfering RNA/cationic liposome complex in mouse models of cancer.

    Junichi Yano;Kazuko Hirabayashi;Shin-ichiro Nakagawa;Tohru Yamaguchi

  • Increased expression of sialyl-dimeric LeX antigen in liver metastases of human colorectal carcinoma.

    Stuart D. Hoff;Yoshifumi Matsushita;David M. Ota;Karen R. Cleary

  • Effects of tunicamycin on B16 metastatic melanoma cell surface glycoproteins and blood-borne arrest and survival properties.

    Tatsuro Irimura;Robert Gonzalez;Garth L. Nicolson

  • Molecular cloning and expression of cDNA encoding human macrophage C-type lectin. Its unique carbohydrate binding specificity for Tn antigen.

    N Suzuki;K Yamamoto;S Toyoshima;T Osawa

  • Expression of MUC1 and MUC2 mucin antigens in intrahepatic bile duct tumors: Its relationship with a new morphological classification of cholangiocarcinoma

    Michiyo Higashi;Suguru Yonezawa;Jenny J. L. Ho;Sadao Tanaka

  • The Macrophage C-type Lectin Specific for Galactose/N-Acetylgalactosamine Is an Endocytic Receptor Expressed on Monocyte-derived Immature Dendritic Cells

    Nobuaki Higashi;Kouki Fujioka;Kaori Denda-Nagai;Shin-ichi Hashimoto

  • Structure of a complex-type sugar chain of human glycophorin A

    Tatsuro Irimura;Tsutomu Tsuji;Setsuro Tagami;Kazuo Yamamoto

  • Chemically modified heparins as inhibitors of heparan sulfate specific endo-.beta.-glucuronidase (heparanase) of metastatic melanoma cells

    Tatsuro Irimura;Motowo Nakajima;Garth L. Nicolson

  • Involvement of carbohydrate antigen sialyl Lewisx in colorectal cancer metastasis

    Shoji Nakamori;Masao Kameyama;Shingi Imaoka;Hiroshi Furukawa

  • Characterization of Human Colon Carcinoma Variant Cells Selected for Sialyl Lex Carbohydrate Antigen: Liver Colonization and Adhesion to Vascular Endothelial Cells

    Yuki Izumi;Yuta Taniuchi;Tsutomu Tsuji;C.Wayne Smith

  • The structure of carbohydrate unit B of porcine thyroglobulin

    K Yamamoto;T Tsuji;T Irimura;T Osawa

  • Carbohydrate-binding specificity of the so-called galactose-specific phytohemagglutinins.

    Tatsuro Irimura;Tsutomu Kawaguchi;Tadao Terao;Toshiaki Osawa

Frequent Co-Authors

Toshiaki Osawa
Toshiaki Osawa University of Tokyo
Kazuo Yamamoto
Kazuo Yamamoto University of Tokyo
Yoshihiro Hayakawa
Yoshihiro Hayakawa Aichi Institute of Technology
Henrik Clausen
Henrik Clausen University of Copenhagen
Hisashi Narimatsu
Hisashi Narimatsu National Institute of Advanced Industrial Science and Technology
Shoji Nakamori
Shoji Nakamori Osaka University
Kazuyoshi Takeda
Kazuyoshi Takeda Juntendo University
Ikuo Saiki
Ikuo Saiki University of Toyama
Yoshihiro Kawaoka
Yoshihiro Kawaoka University of Tokyo
Ayato Takada
Ayato Takada Hokkaido University

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