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Immunology

D-Index
70
Citations
24595
World Ranking
2378
National Ranking
89

Overview

Yoshihiro Hayakawa is affiliated with the Aichi Institute of Technology in Japan. The primary focus of their research lies in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine.

Their work shows a particular emphasis on several subfields, including Molecular Biology, Immunology, Oncology, Pharmacology, and Spectroscopy. Within these areas, the main topics covered are Immune Cell Function and Interaction, Analytical Chemistry and Chromatography, Immunotherapy and Immune Responses, Cancer Immunotherapy and Biomarkers, CAR-T cell therapy research, Natural product bioactivities and synthesis, and Ginger and Zingiberaceae research.

Yoshihiro Hayakawa has a substantial record of publications in various venues. The most frequent publication venues include:

  • Cancer Science
  • Scientific Reports
  • Biological and Pharmaceutical Bulletin
  • Journal of Natural Medicines
  • Journal of Chromatography A

Frequent co-authors who have collaborated extensively with Yoshihiro Hayakawa are:

  • Soichiro Sasaki
  • Satoru Yokoyama
  • Takeshi Susukida
  • Hideyoshi Harashima
  • Hiroaki Sakurai

Recent published papers include:

  • STING agonist loaded lipid nanoparticles overcome anti-PD-1 resistance in melanoma lung metastasis via NK cell activation, 2021, Journal for ImmunoTherapy of Cancer
  • SOX10 Regulates Melanoma Immunogenicity through an IRF4-IRF1 Axis, 2021, Cancer Research
  • Inhibition of cell-intrinsic NF-κB activity and metastatic abilities of breast cancer by aloe-emodin and emodic-acid isolated from Asphodelus microcarpus, 2021, Journal of Natural Medicines
  • Combined nano cancer immunotherapy based on immune status in a tumor microenvironment, 2022, Journal of Controlled Release
  • Pharmacological targeting of natural killer cells for cancer immunotherapy, 2020, Cancer Science

Best Publications

  • STING is a direct innate immune sensor of cyclic di-GMP

    Dara L. Burdette;Kathryn M. Monroe;Katia Sotelo-Troha;Jeff S. Iwig

  • New aspects of natural-killer-cell surveillance and therapy of cancer

    Mark J. Smyth;Yoshihiro Hayakawa;Kazuyoshi Takeda;Hideo Yagita

  • Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells.

    Kazuyoshi Takeda;Yoshihiro Hayakawa;Mark J. Smyth;Nobuhiko Kayagaki

  • Activation of NK cell cytotoxicity.

    Mark J. Smyth;Erika Cretney;Janice M. Kelly;Jennifer A. Westwood

  • CD27 Dissects Mature NK Cells into Two Subsets with Distinct Responsiveness and Migratory Capacity

    Yoshihiro Hayakawa;Mark J. Smyth

  • The Innate Immune DNA Sensor cGAS Produces a Noncanonical Cyclic Dinucleotide that Activates Human STING

    Elie J. Diner;Dara L. Burdette;Stephen C. Wilson;Kathryn M. Monroe

  • The N-Ethyl-N-Nitrosourea-Induced Goldenticket Mouse Mutant Reveals an Essential Function of Sting in the In Vivo Interferon Response to Listeria monocytogenes and Cyclic Dinucleotides

    John Demian Sauer;Katia Sotelo-Troha;Jakob Von Moltke;Kathryn M. Monroe

  • Critical contribution of liver natural killer T cells to a murine model of hepatitis.

    Kazuyoshi Takeda;Yoshihiro Hayakawa;Luc Van Kaer;Hironori Matsuda

  • Critical Role for Tumor Necrosis Factor–related Apoptosis-inducing Ligand in Immune Surveillance Against Tumor Development

    Kazuyoshi Takeda;Mark J. Smyth;Erika Cretney;Yoshihiro Hayakawa

  • CD4+CD25+ T Regulatory Cells Suppress NK Cell-Mediated Immunotherapy of Cancer

    Mark J. Smyth;Michele W. L. Teng;Jeremy Swann;Konstantinos Kyparissoudis

  • Cytokines in cancer immunity and immunotherapy

    Mark J. Smyth;Erika Cretney;Michael H. Kershaw;Yoshihiro Hayakawa

  • Nature's TRAIL: On a path to cancer immunotherapy

    Mark J Smyth;Kazuyoshi Takeda;Yoshihiro Hayakawa;Jacques J Peschon

  • Differential antitumor immunity mediated by NKT cell subsets in vivo.

    Nadine Y. Crowe;Jonathan M. Coquet;Stuart P. Berzins;Konstantinos Kyparissoudis

  • NKG2D function protects the host from tumor initiation

    Mark J. Smyth;Jeremy Swann;Erika Cretney;Nadeen Zerafa

  • IL-21 Induces the Functional Maturation of Murine NK Cells

    Jason Brady;Yoshihiro Hayakawa;Mark J. Smyth;Stephen L. Nutt

  • Type I IFN contributes to NK cell homeostasis, activation, and antitumor function.

    Jeremy B Swann;Yashihiro Hayakawa;Nadeen Zerafa;Kathleen Cf Sheehan

  • NKT cells — conductors of tumor immunity?

    Mark J Smyth;Nadine Y Crowe;Yoshihiro Hayakawa;Kazuyoshi Takeda

  • Glycolipid Antigen Drives Rapid Expansion and Sustained Cytokine Production by NK T Cells

    Nadine Y Crowe;Adam P Uldrich;Konstantinos Kyparissoudis;Kirsten Jenna Louise Hammond

  • NK cell maturation and peripheral homeostasis is associated with KLRG1 up-regulation.

    Nicholas D. Huntington;Nicholas D. Huntington;Hy Tabarias;Hy Tabarias;Kirsten Fairfax;Kirsten Fairfax;Jason Brady

  • The Dark Side of IFN-γ: Its Role in Promoting Cancer Immunoevasion

    Marija Mojic;Kazuyoshi Takeda;Yoshihiro Hayakawa

  • A nonclassical non-Vα14Jα18 CD1d-restricted (type II) NKT cell is sufficient for down-regulation of tumor immunosurveillance

    Masaki Terabe;Jeremy Swann;Elena Ambrosino;Pratima Sinha

  • TRAIL and its receptors as targets for cancer therapy.

    Hideo Yagita;Kazuyoshi Takeda;Yoshihiro Hayakawa;Mark J. Smyth

Frequent Co-Authors

Mark J. Smyth
Mark J. Smyth QIMR Berghofer Medical Research Institute
Ikuo Saiki
Ikuo Saiki University of Toyama
Kazuyoshi Takeda
Kazuyoshi Takeda Juntendo University
Hideo Yagita
Hideo Yagita Juntendo University
Ko Okumura
Ko Okumura Juntendo University
Dale I. Godfrey
Dale I. Godfrey University of Melbourne
Hiroaki Sakurai
Hiroaki Sakurai University of Toyama
Tatsuro Irimura
Tatsuro Irimura Juntendo University
Stephen L. Nutt
Stephen L. Nutt Walter and Eliza Hall Institute of Medical Research
Mariapia A. Degli-Esposti
Mariapia A. Degli-Esposti Monash University

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