Hiroaki Sakurai

Hiroaki Sakurai publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Hiroaki Sakurai sits on this spectrum.

Hiroaki Sakurai D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Hiroaki Sakurai sits on this spectrum.

Overview

Best Publications

• IκB Kinases Phosphorylate NF-κB p65 Subunit on Serine 536 in the Transactivation Domain

  Hiroaki Sakurai;Hiroaki Chiba;Hidetaka Miyoshi;Takahisa Sugita

  1027
  Citations

• Nitric oxide production and inducible nitric oxide synthase expression in inflammatory arthritides

  H Sakurai;H Kohsaka;M F Liu;H Higashiyama

  560
  Citations

• Tumor Necrosis Factor-α-induced IKK Phosphorylation of NF-κB p65 on Serine 536 Is Mediated through the TRAF2, TRAF5, and TAK1 Signaling Pathway

  Hiroaki Sakurai;Shunsuke Suzuki;Noritaka Kawasaki;Hiroyasu Nakano;Hiroyasu Nakano

  479
  Citations

• Distinct Roles of the IκB Kinase α and β Subunits in Liberating Nuclear Factor κB (NF-κB) from IκB and in Phosphorylating the p65 Subunit of NF-κB

  Nywana Sizemore;Natalia Lerner;Nicole Dombrowski;Hiroaki Sakurai

  477
  Citations

• Targeting of TAK1 in inflammatory disorders and cancer

  Hiroaki Sakurai

  396
  Citations

• Receptor Activator of NF-κB Ligand (RANKL) Activates TAK1 Mitogen-Activated Protein Kinase Kinase Kinase through a Signaling Complex Containing RANK, TAB2, and TRAF6

  Junko Mizukami;Giichi Takaesu;Hiroyuki Akatsuka;Hiroaki Sakurai

  338
  Citations

• Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling.

  Masahiro Yamamoto;Toru Okamoto;Kiyoshi Takeda;Shintaro Sato

  333
  Citations

• Role of the CXCL12/CXCR4 Axis in Peritoneal Carcinomatosis of Gastric Cancer

  Kazuo Yasumoto;Keiichi Koizumi;Atsuhiro Kawashima;Yurika Saitoh

  327
  Citations

• Functional Interactions of Transforming Growth Factor β-activated Kinase 1 with IκB Kinases to Stimulate NF-κB Activation

  Hiroaki Sakurai;Hidetaka Miyoshi;Wataru Toriumi;Takahisa Sugita

  284
  Citations

• Critical Roles of Threonine 187 Phosphorylation in Cellular Stress-induced Rapid and Transient Activation of Transforming Growth Factor-β-activated Kinase 1 (TAK1) in a Signaling Complex Containing TAK1-binding Protein TAB1 and TAB2

  Pattama Singhirunnusorn;Shunsuke Suzuki;Noritaka Kawasaki;Ikuo Saiki

  280
  Citations

• High-level expression of chemokine CXCL16 by tumor cells correlates with a good prognosis and increased tumor-infiltrating lymphocytes in colorectal cancer.

  Shozo Hojo;Keiichi Koizumi;Koichi Tsuneyama;Yoshihisa Arita

  224
  Citations

• PKCβ regulates BCR-mediated IKK activation by facilitating the interaction between TAK1 and CARMA1

  Hisaaki Shinohara;Tomoharu Yasuda;Yuichi Aiba;Hideki Sanjo

  224
  Citations

• Vanillin suppresses in vitro invasion and in vivo metastasis of mouse breast cancer cells

  Kriengsak Lirdprapamongkol;Hiroaki Sakurai;Noritaka Kawasaki;Min-Kyung Choo

  222
  Citations

• Phosphorylation-dependent activation of TAK1 mitogen-activated protein kinase kinase kinase by TAB1

  Hiroaki Sakurai;Hidetaka Miyoshi;Junko Mizukami;Takahisa Sugita

  217
  Citations

• Identification of NAP1, a Regulatory Subunit of IκB Kinase-Related Kinases That Potentiates NF-κB Signaling

  Fumitaka Fujita;Yuko Taniguchi;Takashi Kato;Yasuko Narita

  215
  Citations

• Phosphorylation of serine 276 is essential for p65 NF-κB subunit-dependent cellular responses

  Tatsuma Okazaki;Sachiko Sakon;Sachiko Sakon;Tomonari Sasazuki;Tomonari Sasazuki;Hiroaki Sakurai

  200
  Citations

• TAK1 Is Recruited to the Tumor Necrosis Factor-α (TNF-α) Receptor 1 Complex in a Receptor-interacting Protein (RIP)-dependent Manner and Cooperates with MEKK3 Leading to NF-κB Activation

  Marzenna Blonska;Prashant B. Shambharkar;Masayuki Kobayashi;Dongyu Zhang

  184
  Citations

• Insufficient p65 phosphorylation at S536 specifically contributes to the lack of NF-κB activation and transformation in resistant JB6 cells

  Jing Hu;Hiroyasu Nakano;Hiroaki Sakurai;Nancy H. Colburn

  180
  Citations

• Role of CX3CL1/Fractalkine in Osteoclast Differentiation and Bone Resorption

  Keiichi Koizumi;Yurika Saitoh;Takayuki Minami;Nobuhiro Takeno

  177
  Citations

• Angiotensin II plays a pathogenic role in immune-mediated renal injury in mice.

  Yutaka Hisada;Takeshi Sugaya;Masaya Yamanouchi;Hiromi Uchida

  175
  Citations