His primary areas of investigation include Cancer research, Cell biology, Molecular biology, Gene and Transcription factor. He combines subjects such as Carcinogenesis, Cancer, Metastasis and PI3K/AKT/mTOR pathway, PTEN with his study of Cancer research. His Cell biology research integrates issues from Endocrinology and Internal medicine.
His research integrates issues of Interleukin 3, Cell, Genetically modified mouse, Transgene and Growth factor receptor in his study of Molecular biology. His work in the fields of Regulation of gene expression, Germ cell and Germ line development overlaps with other areas such as Klotho. In his work, Cell type, Endothelial cell morphogenesis and FOXO4 is strongly intertwined with Cellular differentiation, which is a subfield of Transcription factor.
Cancer research, Molecular biology, Cell biology, Internal medicine and Genetics are his primary areas of study. The study incorporates disciplines such as Carcinogenesis, Cancer, Tumor suppressor gene, Endometrial cancer and PTEN in addition to Cancer research. His work investigates the relationship between Molecular biology and topics such as Melanoma that intersect with problems in Germline mutation.
His Cell biology study combines topics from a wide range of disciplines, such as Interleukin 3, Transcription factor and Somatic cell. His work in Transcription factor tackles topics such as Cellular differentiation which are related to areas like FOXO4 and Regulation of gene expression. The Internal medicine study combines topics in areas such as Endocrinology and Oncology.
Diego H. Castrillon mostly deals with Cancer research, Endometrial cancer, Cell biology, PTEN and Pathology. His Cancer research research is multidisciplinary, relying on both Carcinogenesis, Cancer, Adenocarcinoma and DNA mismatch repair. His work carried out in the field of Endometrial cancer brings together such families of science as Uterine cancer, PI3K/AKT/mTOR pathway and Hyperplasia.
Diego H. Castrillon studied Cell biology and Germline that intersect with Histone, Mitosis, CHEK1 and Somatic cell. His studies in PTEN integrate themes in fields like Protein kinase B and Carcinoma. His studies deal with areas such as FOXO3 and Molecular biology as well as Ovary.
His main research concerns Cancer research, Adenocarcinoma, PTEN, Stem cell and Cancer. His Cancer research research incorporates themes from Pancreatic cancer, Tumor microenvironment, KRAS, Tumor progression and Kinase. His PTEN research is multidisciplinary, relying on both Carcinogenesis, Mothers against decapentaplegic, SMAD, Granulosa cell and FOXO3.
His work investigates the relationship between Stem cell and topics such as Germline that intersect with problems in Immunology and Transcription factor. His studies in Cancer integrate themes in fields like Phenotype, Proofreading, Polymerase and Allele. As part of his inquiry into Internal medicine and Cell biology, Diego H. Castrillon is doing Receptor tyrosine kinase research.
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FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress.
Zuzana Tothova;Zuzana Tothova;Ramya Kollipara;Brian J. Huntly;Benjamin H. Lee;Benjamin H. Lee.
Cell (2007)
Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis.
Norman E. Sharpless;Nabeel Bardeesy;Kee Ho Lee;Daniel Carrasco.
Nature (2001)
FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis
Ji Hye Paik;Ramya Kollipara;Gerald Chu;Hongkai Ji.
Cell (2007)
LKB1 modulates lung cancer differentiation and metastasis
Hongbin Ji;Matthew R. Ramsey;D. Neil Hayes;Cheng Fan.
Nature (2007)
Suppression of Ovarian Follicle Activation in Mice by the Transcription Factor Foxo3a
Diego H. Castrillon;Lili Miao;Ramya Kollipara;James W. Horner.
Science (2003)
Regulation of oxidative stress by the anti-aging hormone klotho
Masaya Yamamoto;Jeremy D. Clark;Johanne V. Pastor;Prem Gurnani.
Journal of Biological Chemistry (2005)
The human VASA gene is specifically expressed in the germ cell lineage.
Diego H. Castrillon;Bradley J. Quade;T. Y. Wang;Catherine Quigley.
Proceedings of the National Academy of Sciences of the United States of America (2000)
Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor.
Yann M Kerdiles;Daniel R Beisner;Roberto Tinoco;Anne S Dejean.
Nature Immunology (2009)
Control of Male Sexual Behavior and Sexual Orientation in Drosophila by the fruitless Gene
Lisa C Ryner;Stephen F Goodwin;Diego H Castrillon;Anuranjan Anand.
Cell (1996)
diaphanous is required for cytokinesis in Drosophila and shares domains of similarity with the products of the limb deformity gene
Diego H. Castrillon;Steven A. Wasserman.
Development (1994)
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