World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
22717
World Ranking
8975
National Ranking
3988

Overview

Diego H. Castrillon is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research spans multiple fields within medicine and molecular biology with a focus on cancer and immunology.

The scientist has authored numerous papers covering topics such as endometrial and cervical cancer treatments, genetic factors in colorectal cancer, and cancer immunotherapy and biomarkers. The main fields of study for their work include Medicine and Biochemistry, Genetics, and Molecular Biology. Subfields contributing to their research portfolio are Molecular Biology, Obstetrics and Gynecology, Oncology, Immunology, and Pathology and Forensic Medicine.

Key research topics addressed in their publications involve:

  • Endometrial and Cervical Cancer Treatments
  • Genetic factors in colorectal cancer
  • Cancer Immunotherapy and Biomarkers
  • Ovarian cancer diagnosis and treatment
  • Cancer Genomics and Diagnostics
  • Immune Cell Function and Interaction
  • Cervical Cancer and HPV Research

Among recent notable publications are:

  • DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity (2020, Cancer Cell)
  • Dual ARID1A/ARID1B loss leads to rapid carcinogenesis and disruptive redistribution of BAF complexes (2020, Nature Cancer)
  • PD-L1 Expression and CD8+ Tumor-infiltrating Lymphocytes in Different Types of Tubo-ovarian Carcinoma and Their Prognostic Value in High-grade Serous Carcinoma (2020, The American Journal of Surgical Pathology)
  • Loss of p53 and mutational heterogeneity drives immune resistance in an autochthonous mouse lung cancer model with high tumor mutational burden (2023, Cancer Cell)
  • Histopathologic diagnosis of endometrial precancers: Updates and future directions (2021, Seminars in Diagnostic Pathology)

Frequent co-authors collaborating with Diego H. Castrillon include:

  • Elena Lucas
  • Hao Chen
  • Subhransu S. Sahoo
  • Wenxin Zheng
  • Ileana Cuevas

Publication venues where their work is regularly featured comprise a range of specialized and broad scholarly outlets, such as:

  • UNC Libraries
  • The American Journal of Surgical Pathology
  • Modern Pathology
  • Cancer Cell
  • Journal of Clinical Investigation

The scope of Diego H. Castrillon's work reflects an interdisciplinary approach that intersects clinical pathology, cancer biology, and immunology, which supports ongoing advances in cancer diagnosis and treatment strategies.

Best Publications

  • FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress.

    Zuzana Tothova;Zuzana Tothova;Ramya Kollipara;Brian J. Huntly;Benjamin H. Lee;Benjamin H. Lee

  • LKB1 modulates lung cancer differentiation and metastasis

    Hongbin Ji;Matthew R. Ramsey;D. Neil Hayes;Cheng Fan

  • FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis

    Ji Hye Paik;Ramya Kollipara;Gerald Chu;Hongkai Ji

  • Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis.

    Norman E. Sharpless;Nabeel Bardeesy;Kee Ho Lee;Daniel Carrasco

  • Suppression of Ovarian Follicle Activation in Mice by the Transcription Factor Foxo3a

    Diego H. Castrillon;Lili Miao;Ramya Kollipara;James W. Horner

  • Regulation of oxidative stress by the anti-aging hormone klotho

    Masaya Yamamoto;Jeremy D. Clark;Johanne V. Pastor;Prem Gurnani

  • The human VASA gene is specifically expressed in the germ cell lineage

    Diego H. Castrillon;Bradley J. Quade;T. Y. Wang;Catherine Quigley

  • Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor

    Yann M Kerdiles;Daniel R Beisner;Roberto Tinoco;Anne S Dejean

  • Control of Male Sexual Behavior and Sexual Orientation in Drosophila by the fruitless Gene

    Lisa C Ryner;Stephen F Goodwin;Diego H Castrillon;Anuranjan Anand

  • diaphanous is required for cytokinesis in Drosophila and shares domains of similarity with the products of the limb deformity gene

    Diego H. Castrillon;Steven A. Wasserman

  • A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response

    Zhao Chen;Katherine Cheng;Zandra Walton;Yuchuan Wang

  • Toward a Molecular Genetic Analysis of Spermatogenesis in Drosophila Melanogaster: Characterization of Male-Sterile Mutants Generated by Single P Element Mutagenesis

    D. H. Castrillon;P. Gönczy;S. Alexander;R. Rawson

  • Foxo3 is a PI3K-dependent molecular switch controlling the initiation of oocyte growth.

    George B. John;Teresa D. Gallardo;Lane J. Shirley;Diego H. Castrillon

  • Monitoring tumorigenesis and senescence in vivo with a p16(INK4a)-luciferase model.

    Christin E. Burd;Jessica A. Sorrentino;Kelly S. Clark;David B. Darr

  • Constitutive telomerase expression promotes mammary carcinomas in aging mice

    Steven E. Artandi;Steven E. Artandi;Scott Alson;Maja K. Tietze;Maja K. Tietze;Norman E. Sharpless

  • Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation.

    Hart S Dengler;Gisele V Baracho;Sidne A Omori;Shane Bruckner

  • Loss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated PD-L1 Expression

    Chunxiao Xu;Christine M. Fillmore;Shohei Koyama;Hongbo Wu

  • Generation of a germ cell-specific mouse transgenic Cre line, Vasa-Cre

    Teresa Gallardo;Lane Shirley;George B. John;Diego H. Castrillon

  • Foxo transcription factors blunt cardiac hypertrophy by inhibiting calcineurin signaling.

    Yan G. Ni;Kambeez Berenji;Na Wang;Misook Oh

  • Foxo1 is required in mouse spermatogonial stem cells for their maintenance and the initiation of spermatogenesis

    Meredith J. Goertz;Zhuoru Wu;Teresa D. Gallardo;F. Kent Hamra

Frequent Co-Authors

Ronald A. DePinho
Ronald A. DePinho The University of Texas MD Anderson Cancer Center
Kwok-Kin Wong
Kwok-Kin Wong New York University
Norman E. Sharpless
Norman E. Sharpless National Institutes of Health
Nabeel Bardeesy
Nabeel Bardeesy Harvard University
Rolf A. Brekken
Rolf A. Brekken The University of Texas Southwestern Medical Center
Steven A. Wasserman
Steven A. Wasserman University of California, San Diego
Carla F. Kim
Carla F. Kim Boston Children's Hospital
Lynda Chin
Lynda Chin The University of Texas Health Science Center at Houston
Christopher P. Crum
Christopher P. Crum Brigham and Women's Hospital
Yang-Xin Fu
Yang-Xin Fu Tsinghua University

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