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Genetics

D-Index
88
Citations
48944
World Ranking
1144
National Ranking
548

Overview

Michael R. Erdos is affiliated with the National Institutes of Health in the United States. Their research centers on biochemistry, genetics, and molecular biology, with a significant focus on medicine. They have contributed extensively to molecular biology and genetics, alongside substantial involvement in surgery and cancer research.

The primary topics in their research include pancreatic function and diabetes, genetic associations and epidemiology, nuclear structure and function, epigenetics and DNA methylation, diabetes and associated disorders, RNA research and splicing, and CRISPR and genetic engineering.

Among their recent publications are the following:

  • In vivo base editing rescues Hutchinson-Gilford progeria syndrome in mice, 2021, Nature
  • SARS-CoV-2 infection induces beta cell transdifferentiation, 2021, Cell Metabolism
  • Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci, 2022, Nature Communications
  • Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D, 2020, Nature Communications
  • A targeted antisense therapeutic approach for Hutchinson-Gilford progeria syndrome, 2021, Nature Medicine

Frequent co-authors include:

  • Francis S. Collins
  • Narisu Narisu
  • Lori L. Bonnycastle
  • Tingfen Yan
  • Laura J. Scott

The scientist regularly publishes in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Diabetes
  • Zenodo (CERN European Organization for Nuclear Research)
  • The American Journal of Human Genetics

Best Publications

  • Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

    Elizabeth K. Speliotes;Elizabeth K. Speliotes;Cristen J. Willer;Sonja I. Berndt;Keri L. Monda

  • A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.

    Laura J. Scott;Karen L. Mohlke;Lori L. Bonnycastle;Cristen J. Willer

  • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

    Josée Dupuis;Josée Dupuis;Claudia Langenberg;Inga Prokopenko;Richa Saxena;Richa Saxena

  • Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome

    Maria Eriksson;W. Ted Brown;Leslie B. Gordon;Leslie B. Gordon;Michael W. Glynn

  • Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

    E Zeggini;L J Scott;R Saxena;B F Voight

  • Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

    Benjamin F. Voight;Benjamin F. Voight;Laura J. Scott;Valgerdur Steinthorsdottir;Andrew P. Morris

  • Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

    Cristen J. Willer;Elizabeth K. Speliotes;Elizabeth K. Speliotes;Ruth J. F. Loos;Shengxu Li

  • A genome-wide association search for type 2 diabetes genes in African Americans.

    N D Palmer;C W McDonough;P J Hicks;B H Roh

  • Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome.

    Robert D. Goldman;Dale K. Shumaker;Michael R. Erdos;Maria Eriksson

  • Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

    Iris M. Heid;Anne U. Jackson;Joshua C. Randall;Tthomas W. Winkler

  • A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.

    Alisa K. Manning;Alisa K. Manning;Alisa K. Manning;Robert A. Scott;Jonna L. Grimsby

  • Variants in MTNR1B influence fasting glucose levels

    Inga Prokopenko;Claudia Langenberg;Jose C. Florez;Jose C. Florez;Richa Saxena;Richa Saxena

  • Menin Interacts with the AP1 Transcription Factor JunD and Represses JunD-Activated Transcription

    Sunita K. Agarwal;Siradanahalli C. Guru;Christina Heppner;Michael R. Erdos

  • Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging

    Dale K. Shumaker;Thomas Dechat;Alexander Kohlmaier;Alexander Kohlmaier;Stephen A. Adam

  • Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion.

    Valeriya Lyssenko;Cecilia L F Nagorny;Michael R Erdos;Nils Wierup

  • Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

    Richa Saxena;Richa Saxena;Claudia Langenberg;Toshiko Tanaka;Toshiko Tanaka

  • Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants

    Stephen C. J. Parker;Michael L. Stitzel;D. Leland Taylor;Jose Miguel Orozco

  • Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

    Cecilia M. Lindgren;Iris M. Heid;Joshua C. Randall;Claudia Lamina

  • BRCA1 Inhibition of Estrogen Receptor Signaling in Transfected Cells

    S. Fan;J.-A. Wang;R. Yuan;Y. Ma

  • Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (Nature Genetics (2010) 42 (105-116))

    Josée Dupuis;Claudia Langenberg;Inga Prokopenko;Richa Saxena

Frequent Co-Authors

Francis S. Collins
Francis S. Collins National Institutes of Health
Jaakko Tuomilehto
Jaakko Tuomilehto University of Helsinki
Michael Boehnke
Michael Boehnke University of Michigan–Ann Arbor
Laura J. Scott
Laura J. Scott University of Michigan–Ann Arbor
Anne U. Jackson
Anne U. Jackson University of Michigan–Ann Arbor
Richard N. Bergman
Richard N. Bergman Cedars-Sinai Medical Center
Heather M. Stringham
Heather M. Stringham University of Michigan–Ann Arbor
Lori L. Bonnycastle
Lori L. Bonnycastle National Institutes of Health
Karen L. Mohlke
Karen L. Mohlke University of North Carolina at Chapel Hill
Peter S. Chines
Peter S. Chines National Institutes of Health

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