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Reina E. Mebius

Reina E. Mebius

D-Index & Metrics

Immunology

D-Index
69
Citations
24459
World Ranking
2472
National Ranking
97

Overview

Reina E. Mebius is affiliated with Amsterdam UMC in the Netherlands and has a research profile centered on immunology, oncology, and molecular biology. Their work spans multiple subfields including immunology, oncology, molecular biology, biomedical engineering, and surgery.

Their research primarily focuses on topics such as T-cell and B-cell immunology, immunotherapy and immune responses, immune cells in cancer, single-cell and spatial transcriptomics, immune cell function and interaction, pancreatic and hepatic oncology research, and immune response and inflammation.

Recent publications authored or coauthored by Reina E. Mebius include:

  • "Pancreatic cancer-associated fibroblasts modulate macrophage differentiation via sialic acid-Siglec interactions," 2024, Communications Biology
  • "Cancer-on-chip models for metastasis: importance of the tumor microenvironment," 2023, Trends in Biotechnology
  • "Tertiary Lymphoid Structures: Diversity in Their Development, Composition, and Role," 2021, The Journal of Immunology
  • "A molecular map of murine lymph node blood vascular endothelium at single cell resolution," 2020, Nature Communications
  • "Lymph Node Stromal Cells Generate Antigen-Specific Regulatory T Cells and Control Autoreactive T and B Cell Responses," 2020, Cell Reports

They frequently collaborate with a group of coauthors including Charlotte M. de Winde, Jasper J. Koning, Lisa G. M. van Baarsen, Henk P. Roest, and Luc J. W. van der Laan, reflecting an active engagement in collaborative research within their field.

Reina E. Mebius's publications have appeared repeatedly in venues that include bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Immunology, iScience, Trends in Immunology, and Tissue Engineering and Regenerative Medicine.

Best Publications

  • Structure and function of the spleen.

    Reina E. Mebius;Georg Kraal

  • Innate lymphoid cells--a proposal for uniform nomenclature.

    Hergen Spits;David Artis;Marco Colonna;Andreas Diefenbach

  • Innate Lymphoid Cells: 10 Years On.

    Eric Vivier;David Artis;Marco Colonna;Andreas Diefenbach

  • Organogenesis of lymphoid tissues.

    Reina E. Mebius

  • Developing lymph nodes collect CD4+CD3- LTbeta+ cells that can differentiate to APC, NK cells, and follicular cells but not T or B cells

    Reina E Mebius;Paul Rennert;Irving L Weissman

  • Requirement for RORγ in Thymocyte Survival and Lymphoid Organ Development

    Zuoming Sun;Derya Unutmaz;Yong-Rui Zou;Mary Jean Sunshine

  • Dietary Fiber and Bacterial SCFA Enhance Oral Tolerance and Protect against Food Allergy through Diverse Cellular Pathways.

    Jian Tan;Craig McKenzie;Peter J. Vuillermin;Gera Goverse

  • New insights into the development of lymphoid tissues.

    Serge A. van de Pavert;Reina E. Mebius

  • Conduits Mediate Transport of Low-Molecular-Weight Antigen to Lymph Node Follicles

    Ramon Roozendaal;Thorsten R. Mempel;Lisa A. Pitcher;Santiago F. Gonzalez

  • Surface lymphotoxin alpha/beta complex is required for the development of peripheral lymphoid organs.

    P D Rennert;J L Browning;R Mebius;F Mackay

  • Lymphotoxin β receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE−/− mice

    Rolf Gräbner;Katharina Lötzer;Sandra Döpping;Markus Hildner

  • Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity

    Serge A. van de Pavert;Manuela Ferreira;Rita G. Domingues;Hélder Ribeiro

  • Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation.

    Serge A van de Pavert;Brenda J Olivier;Gera Goverse;Mark F Vondenhoff

  • The fetal liver counterpart of adult common lymphoid progenitors gives rise to all lymphoid lineages, CD45+CD4+CD3- cells, as well as macrophages.

    Reina E. Mebius;Toshihiro Miyamoto;Julie Christensen;Jos Domen

  • Regulation of Peripheral Lymph Node Genesis by the Tumor Necrosis Factor Family Member Trance

    Dongku Kim;Reina E. Mebius;John D. MacMicking;Steffen Jung

  • Retinoic Acid and Immune Homeostasis: A Balancing Act

    Martje N. Erkelens;Reina E. Mebius

  • Stromal Cell-Immune Cell Interactions

    Ramon Roozendaal;Reina E. Mebius

  • Expression of the Murine CD27 Ligand CD70 In Vitro and In Vivo

    Kiki Tesselaar;Yanling Xiao;Ramon Arens;Gijs M. W. van Schijndel

  • A Conduit System Distributes Chemokines and Small Blood-borne Molecules through the Splenic White Pulp

    Martijn A Nolte;Jeroen A M Beliën;Inge Schadee-Eestermans;Wendy Jansen

  • Identification of Natural RORγ Ligands that Regulate the Development of Lymphoid Cells

    Fabio R. Santori;Pengxiang Huang;Serge A. van de Pavert;Eugene F. Douglass

  • Expression of retinaldehyde dehydrogenase enzymes in mucosal dendritic cells and gut-draining lymph node stromal cells is controlled by dietary vitamin A.

    Rosalie Molenaar;Marlene Knippenberg;Gera Goverse;Brenda J. Olivier

Frequent Co-Authors

Georg Kraal
Georg Kraal Vrije Universiteit Amsterdam
Irving L. Weissman
Irving L. Weissman Stanford University
Troy D. Randall
Troy D. Randall University of Alabama at Birmingham
Koichi Akashi
Koichi Akashi Kyushu University
Sara A. Michie
Sara A. Michie Stanford University
Paul P. Tak
Paul P. Tak GlaxoSmithKline (United Kingdom)
Helga E. de Vries
Helga E. de Vries University of Amsterdam
Dirk Elewaut
Dirk Elewaut Ghent University
Eugene C. Butcher
Eugene C. Butcher Stanford University
Charles R. Mackay
Charles R. Mackay Qilu University of Technology

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Related Online Degrees & Career Pathways

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Each of these educational pathways complements an immunology background by offering specialized clinical skills, enhancing career versatility in healthcare settings.

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