Marina Cavazzana-Calvo

What is she best known for?

The fields of study she is best known for:

• Gene
• Cancer
• Internal medicine

Marina Cavazzana-Calvo mostly deals with Immunology, Severe combined immunodeficiency, Transplantation, Hematopoietic stem cell transplantation and Genetic enhancement. Her Immunology research is multidisciplinary, relying on both Haematopoiesis and Disease. Marina Cavazzana-Calvo has included themes like Insertional mutagenesis, Cancer research, Internal medicine, Lymphocyte and DNA repair in her Severe combined immunodeficiency study.

She interconnects Survival analysis, Stem cell, Retrospective cohort study and Immunopathology in the investigation of issues within Transplantation. The Hematopoietic stem cell transplantation study combines topics in areas such as Survival rate, Combined immunodeficiencies and Graft-versus-host disease. Her Genetic enhancement research is multidisciplinary, incorporating perspectives in Progenitor cell and Leukemia.

Her most cited work include:

• LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. (3006 citations)
• Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease (2298 citations)
• A Serious Adverse Event after Successful Gene Therapy for X-Linked Severe Combined Immunodeficiency (1589 citations)

What are the main themes of her work throughout her whole career to date?

Her primary areas of study are Immunology, Genetic enhancement, Transplantation, Severe combined immunodeficiency and Stem cell. The study incorporates disciplines such as Progenitor cell, Hematopoietic stem cell transplantation and Haematopoiesis in addition to Immunology. Her work in Genetic enhancement tackles topics such as Combined immunodeficiencies which are related to areas like Transgene.

Her Transplantation study incorporates themes from Immunopathology and Immunodeficiency. Her Severe combined immunodeficiency research incorporates themes from Molecular biology, Cancer research and Virology. Her Stem cell research includes themes of T cell and Cell.

She most often published in these fields:

• Immunology (69.23%)
• Genetic enhancement (44.48%)
• Transplantation (43.14%)

What were the highlights of her more recent work (between 2010-2019)?

• Immunology (69.23%)
• Genetic enhancement (44.48%)
• Severe combined immunodeficiency (39.80%)

In recent papers she was focusing on the following fields of study:

Her scientific interests lie mostly in Immunology, Genetic enhancement, Severe combined immunodeficiency, Transplantation and Stem cell. Her studies in Immunology integrate themes in fields like Hematopoietic stem cell transplantation, Haematopoiesis, Progenitor cell, CD34 and Cell biology. She has researched Genetic enhancement in several fields, including Viral vector and Bioinformatics.

Her Severe combined immunodeficiency study combines topics from a wide range of disciplines, such as Retrovirus, Leukemia, Recombination-activating gene and Virology. Her Transplantation research is included under the broader classification of Internal medicine. Her research integrates issues of Spinal muscular atrophy, Survival of motor neuron, Skeletal muscle, Myocyte and Amniotic stem cells in her study of Stem cell.

Between 2010 and 2019, her most popular works were:

• Long-term outcome and lineage-specific chimerism in 194 patients with Wiskott-Aldrich syndrome treated by hematopoietic cell transplantation in the period 1980-2009: an international collaborative study (205 citations)
• X-linked lymphoproliferative disease due to SAP/SH2D1A deficiency: a multicenter study on the manifestations, management, and outcome of the disease (201 citations)
• Bone marrow failure in Fanconi anemia is triggered by an exacerbated p53/p21 DNA damage response that impairs hematopoietic stem and progenitor cells. (201 citations)

In her most recent research, the most cited papers focused on:

• Gene
• Cancer
• Mutation

Her scientific interests lie mostly in Immunology, Hematopoietic stem cell transplantation, Genetic enhancement, Internal medicine and Severe combined immunodeficiency. Her studies in Immunology integrate themes in fields like Progenitor cell, Haematopoiesis, Stem cell and Amniotic stem cells. Marina Cavazzana-Calvo interconnects X-linked lymphoproliferative disease and Immune dysregulation in the investigation of issues within Hematopoietic stem cell transplantation.

Her Genetic enhancement research is multidisciplinary, relying on both Gene targeting, Hematopoietic stem cell, Viral vector and Bioinformatics. Her specific area of interest is Internal medicine, where she studies Transplantation. Her Severe combined immunodeficiency research includes themes of Leukemia, Wiskott–Aldrich syndrome and Oncology.