D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 82 Citations 34,851 263 World Ranking 10724 National Ranking 316
Biology and Biochemistry D-index 82 Citations 34,843 260 World Ranking 2275 National Ranking 46

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Cancer
  • Internal medicine

Marina Cavazzana-Calvo mostly deals with Immunology, Severe combined immunodeficiency, Transplantation, Hematopoietic stem cell transplantation and Genetic enhancement. Her Immunology research is multidisciplinary, relying on both Haematopoiesis and Disease. Marina Cavazzana-Calvo has included themes like Insertional mutagenesis, Cancer research, Internal medicine, Lymphocyte and DNA repair in her Severe combined immunodeficiency study.

She interconnects Survival analysis, Stem cell, Retrospective cohort study and Immunopathology in the investigation of issues within Transplantation. The Hematopoietic stem cell transplantation study combines topics in areas such as Survival rate, Combined immunodeficiencies and Graft-versus-host disease. Her Genetic enhancement research is multidisciplinary, incorporating perspectives in Progenitor cell and Leukemia.

Her most cited work include:

  • LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. (3006 citations)
  • Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease (2298 citations)
  • A Serious Adverse Event after Successful Gene Therapy for X-Linked Severe Combined Immunodeficiency (1589 citations)

What are the main themes of her work throughout her whole career to date?

Her primary areas of study are Immunology, Genetic enhancement, Transplantation, Severe combined immunodeficiency and Stem cell. The study incorporates disciplines such as Progenitor cell, Hematopoietic stem cell transplantation and Haematopoiesis in addition to Immunology. Her work in Genetic enhancement tackles topics such as Combined immunodeficiencies which are related to areas like Transgene.

Her Transplantation study incorporates themes from Immunopathology and Immunodeficiency. Her Severe combined immunodeficiency research incorporates themes from Molecular biology, Cancer research and Virology. Her Stem cell research includes themes of T cell and Cell.

She most often published in these fields:

  • Immunology (69.23%)
  • Genetic enhancement (44.48%)
  • Transplantation (43.14%)

What were the highlights of her more recent work (between 2010-2019)?

  • Immunology (69.23%)
  • Genetic enhancement (44.48%)
  • Severe combined immunodeficiency (39.80%)

In recent papers she was focusing on the following fields of study:

Her scientific interests lie mostly in Immunology, Genetic enhancement, Severe combined immunodeficiency, Transplantation and Stem cell. Her studies in Immunology integrate themes in fields like Hematopoietic stem cell transplantation, Haematopoiesis, Progenitor cell, CD34 and Cell biology. She has researched Genetic enhancement in several fields, including Viral vector and Bioinformatics.

Her Severe combined immunodeficiency study combines topics from a wide range of disciplines, such as Retrovirus, Leukemia, Recombination-activating gene and Virology. Her Transplantation research is included under the broader classification of Internal medicine. Her research integrates issues of Spinal muscular atrophy, Survival of motor neuron, Skeletal muscle, Myocyte and Amniotic stem cells in her study of Stem cell.

Between 2010 and 2019, her most popular works were:

  • Long-term outcome and lineage-specific chimerism in 194 patients with Wiskott-Aldrich syndrome treated by hematopoietic cell transplantation in the period 1980-2009: an international collaborative study (205 citations)
  • X-linked lymphoproliferative disease due to SAP/SH2D1A deficiency: a multicenter study on the manifestations, management, and outcome of the disease (201 citations)
  • Bone marrow failure in Fanconi anemia is triggered by an exacerbated p53/p21 DNA damage response that impairs hematopoietic stem and progenitor cells. (201 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Mutation

Her scientific interests lie mostly in Immunology, Hematopoietic stem cell transplantation, Genetic enhancement, Internal medicine and Severe combined immunodeficiency. Her studies in Immunology integrate themes in fields like Progenitor cell, Haematopoiesis, Stem cell and Amniotic stem cells. Marina Cavazzana-Calvo interconnects X-linked lymphoproliferative disease and Immune dysregulation in the investigation of issues within Hematopoietic stem cell transplantation.

Her Genetic enhancement research is multidisciplinary, relying on both Gene targeting, Hematopoietic stem cell, Viral vector and Bioinformatics. Her specific area of interest is Internal medicine, where she studies Transplantation. Her Severe combined immunodeficiency research includes themes of Leukemia, Wiskott–Aldrich syndrome and Oncology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1.

S. Hacein-Bey-Abina;C. Von Kalle;C. Von Kalle;M. Schmidt;M. P. McCormack.
Science (2003)

4217 Citations

Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

Marina Cavazzana-Calvo;Salima Hacein-Bey;Geneviève De Saint Basile;Fabian Gross.
Science (2000)

3347 Citations

A Serious Adverse Event after Successful Gene Therapy for X-Linked Severe Combined Immunodeficiency

Salima Hacein-Bey-Abina;Christof Von Kalle;Manfred Schmidt;Françoise Le Deist.
The New England Journal of Medicine (2003)

2312 Citations

Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1

Salima Hacein-Bey-Abina;Alexandrine Garrigue;Gary P. Wang;Jean Soulier.
Journal of Clinical Investigation (2008)

1898 Citations

Hematopoietic Stem Cell Gene Therapy with a Lentiviral Vector in X-Linked Adrenoleukodystrophy

Nathalie Cartier;Salima Hacein-Bey-Abina;Cynthia C. Bartholomae;Gabor Veres.
Science (2009)

1606 Citations

Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia

Marina Cavazzana-Calvo;Emmanuel Payen;Olivier Negre;Gary Wang.
Nature (2010)

1465 Citations

Sustained Correction of X-Linked Severe Combined Immunodeficiency by ex Vivo Gene Therapy

Salima Hacein-Bey-Abina;Françoise Le Deist;Frédérique Carlier;Cécile Bouneaud.
The New England Journal of Medicine (2002)

1411 Citations

Artemis, a Novel DNA Double-Strand Break Repair/V(D)J Recombination Protein, Is Mutated in Human Severe Combined Immune Deficiency

Despina Moshous;Isabelle Callebaut;Régina de Chasseval;Barbara Corneo.
Cell (2001)

1032 Citations

Efficacy of Gene Therapy for X-Linked Severe Combined Immunodeficiency

Salima Hacein-Bey-Abina;Julia Hauer;Annick Lim;Capucine Picard.
The New England Journal of Medicine (2010)

688 Citations

Long-term survival and transplantation of haemopoietic stem cells for immunodeficiencies: report of the European experience 1968–99

Corinne Antoine;Susanna Müller;Andrew Cant;Marina Cavazzana-Calvo.
The Lancet (2003)

596 Citations

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