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Ming-Zong Lai

Ming-Zong Lai

D-Index & Metrics

Biology and Biochemistry

D-Index
43
Citations
5247
World Ranking
19434
National Ranking
93

Overview

Ming-Zong Lai is a researcher affiliated with Academia Sinica in Taiwan, with a focus on several intersecting fields in life sciences. Their work spans Biochemistry, Genetics and Molecular Biology, Immunology and Microbiology, and Medicine, with a particular emphasis on subfields such as Immunology, Molecular Biology, Oncology, Pulmonary and Respiratory Medicine, and Biomaterials.

Their research covers a variety of main topics including cell death mechanisms and regulation, immune cell function and interaction, immune cells in cancer, trace elements in health, inflammasome and immune disorders, cancer hypoxia and metabolism, and NF-κB signaling pathways.

Recent papers authored or co-authored by Ming-Zong Lai include:

  • "HIF-2α is indispensable for regulatory T cell function" (2020, Nature Communications)
  • "Tumor suppressor death-associated protein kinase 1 inhibits necroptosis by p38 MAPK activation" (2020, Cell Death and Disease)
  • "Caspase-8 inactivation drives autophagy-dependent inflammasome activation in myeloid cells" (2022, Science Advances)
  • "Infection-induced inflammation from specific inborn errors of immunity to COVID-19" (2021, FEBS Journal)
  • "Promyelocytic leukemia protein targets MK2 to promote cytotoxicity" (2021, EMBO Reports)

Collaborations have frequently involved several co-authors including Shu-Ting Mo, Yung-Hsuan Wu, Fu-Yi Hsieh, Hsuan-Yin Pan, and Ting-Fang Chou, reflecting an active engagement in cooperative research efforts.

Ming-Zong Lai's work has been published in a range of scientific journals, with multiple publications appearing in Annals of Oncology, as well as contributions to Nature Communications, Cell Death and Disease, Science Advances, and FEBS Journal.

Best Publications

  • Immunological self, nonself discrimination.

    Jean-Gerard Guillet;Ming-Zong Lai;Thomas J. Briner;Soren Buus

  • Efficiency of cytoplasmic delivery by pH-sensitive liposomes to cells in culture.

    Chun-Jung Chu;Jan Dijkstra;Ming-Zong Lai;Keelung Hong

  • Interaction of peptide antigens and class II major histocompatibility complex antigens.

    Jean-Gerrard Guillet;Ming-Zong Lai;Thomas J. Briner;John A. Smith

  • Fibronectin-mediated uptake of gelatin-coated latex particles by peritoneal macrophages.

    P W Gudewicz;J Molnar;M Z Lai;D W Beezhold

  • DNA-damaging reagents induce apoptosis through reactive oxygen species-dependent Fas aggregation.

    Huey-Lan Huang;Li-Wen Fang;Shu-Ping Lu;Chen-Kung Chou

  • Effects of replacement of the hydroxyl group of cholesterol and tocopherol on the thermotropic behavior of phospholipid membranes.

    Ming Zong Lai;Nejat Duzgunes;Francis C. Szoka

  • Mitogen-activated Protein Kinase Kinase Antagonized Fas-associated Death Domain Protein-mediated Apoptosis by Induced FLICE-inhibitory Protein Expression

    Jung-Hua Yeh;Shu-Ching Hsu;Shou-Hwa Han;Ming-Zong Lai

  • c-Jun N-terminal Kinase but Not Mitogen-activated Protein Kinase Is Sensitive to cAMP Inhibition in T Lymphocytes

    Yi-Ping Hsueh;Yi-Ping Hsueh;Ming-Zong Lai;Ming-Zong Lai

  • Nitric oxide increased interleukin‐4 expression in T lymphocytes

    R.-H. Chang;M.-H. Lin Feng;W.-H. Liu;M.-Z. Lai

  • Interleukin-3 stimulation of mcl-1 gene transcription involves activation of the PU.1 transcription factor through a p38 mitogen-activated protein kinase-dependent pathway.

    Ju Ming Wang;Ming Zong Lai;Hsin Fang Yang-Yen

  • Promyelocytic Leukemia Protein (PML) Functions as a Glucocorticoid Receptor Co-activator by Sequestering Daxx to the PML Oncogenic Domains (PODs) to Enhance Its Transactivation Potential

    Ding Yen Lin;Ming Zong Lai;David K. Ann;Hsiu Ming Shih

  • Acid- and calcium-induced structural changes in phosphatidylethanolamine membranes stabilized by cholesteryl hemisuccinate.

    Ming Zong Lai;William J. Vail;Francis C. Szoka

  • p38 Mitogen-activated Protein Kinase Is Involved in Fas Ligand Expression

    Shu-Ching Hsu;Shu-Ching Hsu;Mikhail A. Gavrilin;Meng-Hong Tsai;Meng-Hong Tsai;Jiahuai Han

  • Nuclear factor of activated T cells c is a target of p38 mitogen-activated protein kinase in T cells

    Chia-Cheng Wu;Chia-Cheng Wu;Shu-Ching Hsu;Hsiu-ming Shih;Ming-Zong Lai;Ming-Zong Lai;Ming-Zong Lai

  • NF‐κB‐dependent Fas ligand expression

    Shu-Ching Hsu;Mikhail A. Gavrilin;Hsiu-Hsiang Lee;Chia-Cheng Wu;Chia-Cheng Wu

  • HIF-2α is indispensable for regulatory T cell function.

    Tzu-Sheng Hsu;Yen-Lin Lin;Yu-An Wang;Shu-Ting Mo

  • T lymphocyte response to bacteriophage lambda repressor cI protein. Recognition of the same peptide presented by Ia molecules of different haplotypes.

    Ming-Zong Lai;D. T. Ross;J.-G. Guillet;T. J. Briner

  • Reactive oxygen species promote raft formation in T lymphocytes

    Shu-Ping Lu;Ming-Hsien Lin Feng;Huey-Lan Huang;Ya-Ching Huang;Ya-Ching Huang

  • Notch inhibits apoptosis by direct interference with XIAP ubiquitination and degradation

    Wen-Hsien Liu;Huey-Wen Hsiao;Huey-Wen Hsiao;Wen-I Tsou;Ming-Zong Lai;Ming-Zong Lai;Ming-Zong Lai

  • Deltex1 Is a Target of the Transcription Factor NFAT that Promotes T Cell Anergy

    Huey-Wen Hsiao;Wen-Hsien Liu;Chen-Jhe Wang;Yu-Hsun Lo

Frequent Co-Authors

Ruey-Hwa Chen
Ruey-Hwa Chen Academia Sinica
Shie-Liang Hsieh
Shie-Liang Hsieh Academia Sinica
John A. Smith
John A. Smith University of Alabama at Birmingham
Adi Kimchi
Adi Kimchi Weizmann Institute of Science
Francis C. Szoka
Francis C. Szoka University of California, San Francisco
Chih-Hsin Tang
Chih-Hsin Tang China Medical University
You-Wen He
You-Wen He Duke University
Jiahuai Han
Jiahuai Han Xiamen University
Tien-Yau Luh
Tien-Yau Luh National Taiwan University

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