2019 - Fellow, National Academy of Inventors
His main research concerns Liposome, Biochemistry, Vesicle, Biophysics and Cationic polymerization. His Liposome research incorporates themes from Ethylene glycol, Drug delivery, Chromatography, Phosphatidylethanolamine and In vivo. He combines subjects such as Phospholipid, Phosphatidylcholine, Lipid bilayer and Aqueous solution with his study of Vesicle.
His Biophysics research is multidisciplinary, incorporating perspectives in Oligonucleotide and Biodistribution. His biological study spans a wide range of topics, including Crystallography, Polylysine, Complement system and Polymer. Francis C. Szoka works mostly in the field of DNA, limiting it down to concerns involving Dendrimer and, occasionally, Polynucleotide.
His primary scientific interests are in Liposome, Biochemistry, Biophysics, Vesicle and Pharmacology. His research integrates issues of Drug, Bilayer, Drug delivery, Chromatography and In vivo in his study of Liposome. His work in the fields of Drug delivery, such as Drug carrier, intersects with other areas such as Conjugate.
Francis C. Szoka focuses mostly in the field of Biochemistry, narrowing it down to matters related to Cationic polymerization and, in some cases, Cationic liposome. His research investigates the connection between Vesicle and topics such as Phospholipid that intersect with problems in Biological membrane. The concepts of his Pharmacology study are interwoven with issues in Amphotericin B and Toxicity.
Francis C. Szoka mainly investigates Liposome, Biochemistry, Drug delivery, Biophysics and In vivo. He has included themes like Phosphocholine, Phosphatidylcholine, Chromatography and Pharmacology, Drug in his Liposome study. The concepts of his Drug study are interwoven with issues in Nanotechnology and Aqueous solution.
Francis C. Szoka has included themes like Tumor microenvironment, Autoimmune disease, Carboxylate, Stereochemistry and Amine gas treating in his Drug delivery study. Francis C. Szoka combines subjects such as Glycation, In vitro, Small molecule and Matrix with his study of Biophysics. His work carried out in the field of In vivo brings together such families of science as Extracellular matrix, Central nervous system, Cationic liposome and Rho-associated protein kinase.
Liposome, Drug delivery, Pharmacology, Drug and Immunology are his primary areas of study. His research in Liposome intersects with topics in Chromatography, Targeted drug delivery, Polymer chemistry and Cytotoxicity. His Targeted drug delivery study combines topics in areas such as Biophysics, Cationic liposome, Immunogenicity, Membrane and In vivo.
His biological study spans a wide range of topics, including Pharmacokinetics, Immunoglobulin G, Autoimmune disease, Protein subunit and Regulator. His Pharmacology study incorporates themes from Tumor microenvironment, Hyaluronic acid and Doxorubicin. His Drug study integrates concerns from other disciplines, such as Clinical trial, Nanotechnology and Aqueous solution.
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Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation
Francis Szoka;Demetrios Papahadjopoulos.
Proceedings of the National Academy of Sciences of the United States of America (1978)
Comparative Properties and Methods of Preparation of Lipid Vesicles (Liposomes)
F Szoka;D Papahadjopoulos.
Annual Review of Biophysics and Bioengineering (1980)
Designing dendrimers for biological applications
Cameron C Lee;John A MacKay;Jean M J Fréchet;Francis C Szoka.
Nature Biotechnology (2005)
Polyamidoamine cascade polymers mediate efficient transfection of cells in culture
Jean Haensler;Francis C. Szoka.
Bioconjugate Chemistry (1993)
Preparation of liposomes of defined size distribution by extrusion through polycarbonate membranes
F. Olson;C.A. Hunt;F.C. Szoka;W.J. Vail.
Biochimica et Biophysica Acta (1979)
Method of encapsulating biologically active materials in lipid vesicles
Demetrios P. Papahadjopoulos;Francis C. Szoka.
(1978)
Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection.
Yuhong Xu;Francis C. Szoka.
Biochemistry (1996)
In Vitro Gene Delivery by Degraded Polyamidoamine Dendrimers
Mary X. Tang;Carl T. Redemann;Francis C. Szoka.
Bioconjugate Chemistry (1996)
The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes
M X Tang;F C Szoka;F C Szoka.
Gene Therapy (1997)
Mechanism of oligonucleotide release from cationic liposomes.
Olivier Zelphati;Francis C. Szoka.
Proceedings of the National Academy of Sciences of the United States of America (1996)
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