World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
100
Citations
51016
World Ranking
1246
National Ranking
482

Research.com Recognitions

  • 2019 - Fellow, National Academy of Inventors

Overview

Francis C. Szoka is affiliated with the University of California, San Francisco, located in the United States. Their research spans several interconnected fields, including Biochemistry, Genetics and Molecular Biology as well as Immunology and Microbiology. The subfields in which they have contributed include Molecular Biology, Virology, Biomaterials, Radiology, Nuclear Medicine and Imaging, and Immunology.

The scientist's work covers main topics such as:

  • HIV Research and Treatment
  • Lipid Membrane Structure and Behavior
  • Protein Structure and Dynamics
  • Nanoparticle-Based Drug Delivery
  • Ubiquitin and proteasome pathways
  • Protein Degradation and Inhibitors
  • Monoclonal and Polyclonal Antibodies Research

Recent publications by Francis C. Szoka include:

  • "Biophysical studies of HIV-1 glycoprotein-41 interactions with peptides and small molecules - Effect of lipids and detergents," 2020, published in Biochimica et Biophysica Acta (BBA) - General Subjects
  • "Liposome Formulation of Carfilzomib with Improved Activity As a Monotherapy and in Combination with Vinblastine," 2022, published in Blood
  • "A hitchhiker's guide to mucosal and systemic immunity," 2022, published in Science Translational Medicine

Frequent co-authors collaborating with Szoka include:

  • Guangyan Zhou
  • Shidong Chu
  • Aditya Kohli
  • Miriam Gochin
  • Charles O. Noble

Throughout their scientific career, Francis C. Szoka has contributed to publications in venues such as Biochimica et Biophysica Acta (BBA) - General Subjects, Blood, and Science Translational Medicine. This involvement illustrates a focus on interdisciplinary research connecting biophysical studies, immunology, and clinical applications.

In recognition of their work, Szoka was named Fellow of the National Academy of Inventors in 2019.

Best Publications

  • Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation

    Francis Szoka;Demetrios Papahadjopoulos

  • Designing dendrimers for biological applications.

    Cameron C Lee;John A MacKay;Jean M J Fréchet;Francis C Szoka

  • Comparative Properties and Methods of Preparation of Lipid Vesicles (Liposomes)

    F Szoka;D Papahadjopoulos

  • Polyamidoamine cascade polymers mediate efficient transfection of cells in culture

    Jean Haensler;Francis C. Szoka

  • Preparation of liposomes of defined size distribution by extrusion through polycarbonate membranes

    F. Olson;C.A. Hunt;F.C. Szoka;W.J. Vail

  • Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection.

    Yuhong Xu;Francis C. Szoka

  • Method of encapsulating biologically active materials in lipid vesicles

    Demetrios P. Papahadjopoulos;Francis C. Szoka

  • In Vitro Gene Delivery by Degraded Polyamidoamine Dendrimers

    Mary X. Tang;Carl T. Redemann;Francis C. Szoka

  • The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes

    M X Tang;F C Szoka;F C Szoka

  • Soluble polymer carriers for the treatment of cancer: The importance of molecular architecture

    Megan E. Fox;Francis C. Szoka;Jean M. J. Fréchet

  • Mechanism of oligonucleotide release from cationic liposomes.

    Olivier Zelphati;Francis C. Szoka

  • Lipid-based nanoparticles for nucleic acid delivery

    Weijun Li;Weijun Li;Francis C. Szoka

  • Activation of the Complement System by Synthetic DNA Complexes: A Potential Barrier for Intravenous Gene Delivery

    Christian Plank;Karl Mechtler;Francis C. Szoka;Ernst Wagner

  • A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas.

    Cameron C. Lee;Elizabeth R. Gillies;Megan E. Fox;Steven J. Guillaudeu

  • GALA: a designed synthetic pH-responsive amphipathic peptide with applications in drug and gene delivery.

    Weijun Li;François Nicol;François Nicol;Francis C Szoka

  • H+- and Ca2+-induced fusion and destabilization of liposomes

    Harma Ellens;Joe Bentz;Francis C. Szoka

  • Polyester dendritic systems for drug delivery applications: in vitro and in vivo evaluation.

    Omayra L. Padilla De Jesus;Henrik R. Ihre;Lucie Gagne;Jean M. J. Frechet

  • Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers.

    Tara B. Wyman;François Nicol;Olivier Zelphati;P. V. Scaria

  • pH-Induced destabilization of phosphatidylethanolamine-containing liposomes: role of bilayer contact

    Harma Ellens;Joe Bentz;Francis C. Szoka

  • Nomenclature for Synthetic Gene Delivery Systems

    P. L. Felgner;Y. Barenholz;J. P. Behr;S. H. Cheng

Frequent Co-Authors

Jean M. J. Fréchet
Jean M. J. Fréchet University of California, Berkeley
Demetrios Papahadjopoulos
Demetrios Papahadjopoulos University of California, San Francisco
Shlomo Nir
Shlomo Nir Hebrew University of Jerusalem
Richard H. Guy
Richard H. Guy University of Bath
Michael Barza
Michael Barza Tufts Medical Center
Mahmoud Reza Jaafari
Mahmoud Reza Jaafari Mashhad University of Medical Sciences
Gerald Zon
Gerald Zon TriLink BioTechnologies (United States)
Ming-Zong Lai
Ming-Zong Lai Academia Sinica
Ernst Wagner
Ernst Wagner Ludwig-Maximilians-Universität München
Victor A. Kabanov
Victor A. Kabanov Lomonosov Moscow State University

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