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Biology and Biochemistry
Iran
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
69
Citations
14855
World Ranking
7508
National Ranking
6

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Iran Leader Award
  • 2025 - Research.com Biology and Biochemistry in Iran Leader Award

Overview

Mahmoud Reza Jaafari is affiliated with Mashhad University of Medical Sciences in Iran. Their research spans primarily across the fields of biochemistry, genetics, molecular biology, and medicine, with a significant focus on molecular biology, biomaterials, immunology, biomedical engineering, and oncology as subfields.

Their work frequently addresses topics related to nanoparticle-based drug delivery, RNA interference and gene delivery, nanoplatforms for cancer theranostics, immunotherapy and immune responses, curcumin's biomedical applications, advanced drug delivery systems, and graphene and nanomaterials applications.

Jaafari has coauthored numerous publications with recurrent collaborators including Mohammad Mashreghi, Ali Badiee, Seyedeh Hoda Alavizadeh, Leila Arabi, and Amirhossein Sahebkar.

They have contributed extensively to a variety of scientific journals, with a high number of publications in the following venues:

  • Journal of Drug Delivery Science and Technology
  • International Journal of Pharmaceutics
  • Scientific Reports
  • PubMed
  • DOAJ (DOAJ: Directory of Open Access Journals)

Notable recent papers include:

  • "Toxicity assessment of superparamagnetic iron oxide nanoparticles in different tissues", 2020, Artificial Cells Nanomedicine and Biotechnology
  • "Oral nano-curcumin formulation efficacy in management of mild to moderate hospitalized coronavirus disease-19 patients: An open label nonrandomized clinical trial", 2021, Phytotherapy Research
  • "Application of ensemble machine learning approach to assess the factors affecting size and polydispersity index of liposomal nanoparticles", 2023, Scientific Reports
  • "Redox-sensitive nanoscale drug delivery systems for cancer treatment", 2020, International Journal of Pharmaceutics
  • "Optimization of Docetaxel Loading Conditions in Liposomes: proposing potential products for metastatic breast carcinoma chemotherapy", 2020, Scientific Reports

Best Publications

  • MicroRNA: A novel target of curcumin in cancer therapy.

    Hamed Mirzaei;Aria Masoudifar;Amirhossein Sahebkar;Naser Zare

  • Sesquiterpene coumarins from Ferula szowitsiana and in vitro antileishmanial activity of 7-prenyloxycoumarins against promastigotes

    Mehrdad Iranshahi;Peyman Arfa;Mohammad Ramezani;Mahmoud Reza Jaafari

  • Exosome-mediated delivery of functionally active miRNA-142-3p inhibitor reduces tumorigenicity of breast cancer in vitro and in vivo.

    Zahra Naseri;Reza Kazemi Oskuee;Mahmoud Reza Jaafari;Mehdi Forouzandeh Moghadam

  • Perspective of Fe3O4 Nanoparticles Role in Biomedical Applications.

    Mohammad Reza Ghazanfari;Mehrdad Kashefi;Seyyedeh Fatemeh Shams;Mahmoud Reza Jaafari

  • The effect of nano-curcumin on HbA1c, fasting blood glucose, and lipid profile in diabetic subjects: a randomized clinical trial

    Hamid Reza Rahimi;Amir Hooshang Mohammadpour;Mostafa Dastani;Mahmoud Reza Jaafari

  • PREPARATION, CHARACTERIZATION, AND IN VIVO EVALUATION OF NANOLIPOSOMES-ENCAPSULATED BEVACIZUMAB (AVASTIN) FOR INTRAVITREAL ADMINISTRATION

    Majid Abrishami;Siamak Zarei Ganavati;Dina Soroush;Majid Rouhbakhsh

  • MicroRNA: Relevance to stroke diagnosis, prognosis, and therapy

    Hamed Mirzaei;Fatemeh Momeni;Leila Saadatpour;Amirhossein Sahebkar

  • Enhancement of follicular delivery of finasteride by liposomes and niosomes 1. In vitro permeation and in vivo deposition studies using hamster flank and ear models.

    Majid Tabbakhian;Naser Tavakoli;Mahmoud Reza Jaafari;Saeid Daneshamouz

  • MicroRNAs as potential diagnostic and prognostic biomarkers in melanoma.

    Hamed Mirzaei;Sharareh Gholamin;Soodabeh Shahidsales;Amirhossein Sahebkar

  • Targeting CD44 expressing cancer cells with anti-CD44 monoclonal antibody improves cellular uptake and antitumor efficacy of liposomal doxorubicin.

    Leila Arabi;Ali Badiee;Fatemeh Mosaffa;Mahmoud Reza Jaafari

  • CD47: role in the immune system and application to cancer therapy.

    Seyed Mohammad Gheibi Hayat;Vanessa Bianconi;Matteo Pirro;Mahmoud R Jaafari

  • Diagnostic and Therapeutic Potential of Exosomes in Cancer: The Beginning of a New Tale?

    Hamed Mirzaei;Amirhossein Sahebkar;Mahmoud Reza Jaafari;Mohammad Goodarzi

  • Circulating microRNAs in Hepatocellular Carcinoma: Potential Diagnostic and Prognostic Biomarkers

    Hamid Reza Mirzaei;Amirhossein Sahebkar;Mohsen Mohammadi;Reza Yari

  • Improving Multi-Epitope Long Peptide Vaccine Potency by Using a Strategy that Enhances CD4+ T Help in BALB/c Mice.

    Haniyeh Ghaffari-Nazari;Jalil Tavakkol-Afshari;Mahmoud Reza Jaafari;Sahar Tahaghoghi-Hajghorbani

  • Epirubicin loaded super paramagnetic iron oxide nanoparticle-aptamer bioconjugate for combined colon cancer therapy and imaging in vivo.

    Seyed Hamid Jalalian;Seyed Mohammad Taghdisi;Nasim Shahidi Hamedani;Seyedeh Alia Moosavian Kalat

  • Toxicity assessment of superparamagnetic iron oxide nanoparticles in different tissues

    Roghayyeh Vakili-Ghartavol;Amir Abbas Momtazi-Borojeni;Zeynab Vakili-Ghartavol;Hammed Tanimowo Aiyelabegan

  • The role of CpG ODN in enhancement of immune response and protection in BALB/c mice immunized with recombinant major surface glycoprotein of Leishmania (rgp63) encapsulated in cationic liposome.

    Mahmoud R Jaafari;Ali Badiee;Ali Khamesipour;Afshin Samiei

  • Epi-Drugs and Epi-miRs: Moving Beyond Current Cancer Therapies.

    Reza Salarinia;Amirhossein Sahebkar;Mostafa Peyvandi;Hamid Reza Mirzaei

  • Disterolphospholipids: nonexchangeable lipids and their application to liposomal drug delivery.

    Zhaohua Huang;Mahmoud Reza Jaafari;Mahmoud Reza Jaafari;Francis C. Szoka

  • A novel target of curcumin in cancer therapy

    Hamed Mirzaei;Aria Masoudifar;Amirhossein Sahebkar;Naser Zare

Frequent Co-Authors

Amirhossein Sahebkar
Amirhossein Sahebkar Mashhad University of Medical Sciences
Hamed Mirzaei
Hamed Mirzaei Kashan University of Medical Sciences
Maciej Banach
Maciej Banach John Paul II Catholic University of Lublin
Khalil Abnous
Khalil Abnous Mashhad University of Medical Sciences
Mehrdad Iranshahi
Mehrdad Iranshahi Mashhad University of Medical Sciences
Mohammad Ramezani
Mohammad Ramezani Mashhad University of Medical Sciences
Hossein Hosseinzadeh
Hossein Hosseinzadeh Mashhad University of Medical Sciences
Saman Hosseinkhani
Saman Hosseinkhani Tarbiat Modares University
Hossein Baharvand
Hossein Baharvand Royan Institute
Amir Avan
Amir Avan Mashhad University of Medical Sciences

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