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Juan José Lasarte

Juan José Lasarte

D-Index & Metrics

Immunology

D-Index
60
Citations
12289
World Ranking
3340
National Ranking
37

Overview

Juan José Lasarte is affiliated with the University of Navarra in Spain. Their research spans multiple fields within biomedical science, focusing primarily on medicine, immunology and microbiology, and biochemistry, genetics and molecular biology. Their work explores key subfields such as immunology, oncology, molecular biology, hematology, and infectious diseases.

The scientist's research concentrates on several main topics including CAR-T cell therapy research, immunotherapy and immune responses, immune cell function and interaction, cancer immunotherapy and biomarkers, biosimilars and bioanalytical methods, viral infectious diseases and gene expression in insects, and multiple myeloma research and treatments.

Juan José Lasarte has published extensively in a number of scientific journals. The most frequent publication venues include:

  • Blood
  • Journal for ImmunoTherapy of Cancer
  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Clinical Lymphoma Myeloma & Leukemia

Frequent co-authors collaborating with Juan José Lasarte include:

  • Felipe Prósper
  • Teresa Lozano
  • Juan R. Rodriguez-Madoz
  • Noëlia Casares
  • Susana Inogès

Some of the recent papers associated with their research are:

  • "Consensus guidelines for the definition, detection and interpretation of immunogenic cell death," 2020, Journal for ImmunoTherapy of Cancer
  • "Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade," 2020, Nature Cancer
  • "CAR density influences antitumoral efficacy of BCMA CAR T cells and correlates with clinical outcome," 2022, Science Advances
  • "SRC family kinase (SFK) inhibitor dasatinib improves the antitumor activity of anti-PD-1 in NSCLC models by inhibiting Treg cell conversion and proliferation," 2021, Journal for ImmunoTherapy of Cancer
  • "The TGF-β Pathway: A Pharmacological Target in Hepatocellular Carcinoma?" 2021, Cancers

Best Publications

  • A clinical trial of CTLA-4 blockade with tremelimumab in patients with hepatocellular carcinoma and chronic hepatitis C.

    Bruno Sangro;Carlos Gomez-Martin;Manuel de la Mata;Mercedes Iñarrairaegui

  • Consensus guidelines for the definition, detection and interpretation of immunogenic cell death

    Lorenzo Galluzzi;Ilio Vitale;Sarah Warren;Sandy Adjemian

  • Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy.

    Yuting Ma;Laetitia Aymeric;Clara Locher;Stephen R Mattarollo

  • Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy

    Yuting Ma;Yuting Ma;Laetitia Aymeric;Laetitia Aymeric;Clara Locher;Clara Locher;Stephen R. Mattarollo

  • Anaphylatoxin C5a creates a favorable microenvironment for lung cancer progression.

    Leticia Corrales;Daniel Ajona;Stavros Rafail;Juan J. Lasarte

  • CD4+/CD25+ Regulatory Cells Inhibit Activation of Tumor-Primed CD4+ T Cells with IFN-γ-Dependent Antiangiogenic Activity, as well as Long-Lasting Tumor Immunity Elicited by Peptide Vaccination

    Noelia Casares;Laura Arribillaga;Pablo Sarobe;Javier Dotor

  • Transmission of hepatitis C virus infection to tree shrews.

    Zhi-Chun Xie;Jose-Ignacio Riezu-Boj;Juan-Jose Lasarte;Javier Guillen

  • A Combined PD-1/C5a Blockade Synergistically Protects against Lung Cancer Growth and Metastasis

    Daniel Ajona;Sergio Ortiz-Espinosa;Haritz Moreno;Teresa Lozano

  • Abnormal Priming of CD4+ T Cells by Dendritic Cells Expressing Hepatitis C Virus Core and E1 Proteins

    Pablo Sarobe;Juan José Lasarte;Noelia Casares;Ascensión López-Díaz de Cerio

  • Topical Application of a Peptide Inhibitor of Transforming Growth Factor-β1 Ameliorates Bleomycin-Induced Skin Fibrosis

    Begoña Santiago;Irene Gutierrez-Cañas;Javier Dotor;Guillermo Palao

  • Hepatitis C Virus Structural Proteins Impair Dendritic Cell Maturation and Inhibit In Vivo Induction of Cellular Immune Responses

    Pablo Sarobe;Juan José Lasarte;Aintzane Zabaleta;Laura Arribillaga

  • Inhibition of a G9a/DNMT network triggers immune-mediated bladder cancer regression.

    Cristina Segovia;Edurne San José-Enériz;Ester Munera-Maravilla;Mónica Martínez-Fernández

  • Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies.

    Edurne San José-Enériz;Xabier Agirre;Obdulia Rabal;Amaia Vilas-Zornoza

  • Expansion of Tumor-Infiltrating CD8+ T cells Expressing PD-1 Improves the Efficacy of Adoptive T-cell Therapy.

    Sarita M. Fernandez-Poma;Diego Salas-Benito;Teresa Lozano;Noelia Casares

  • A synthetic peptide from transforming growth factor beta type III receptor inhibits liver fibrogenesis in rats with carbon tetrachloride liver injury.

    Ignacio-José Ezquerro;Juan-José Lasarte;Javier Dotor;Inma Castilla-Cortázar

  • Upregulation of Indoleamine 2,3-Dioxygenase in Hepatitis C Virus Infection

    Esther Larrea;José I. Riezu-Boj;Lucía Gil-Guerrero;Noelia Casares

  • A synthetic peptide from transforming growth factor-beta1 type III receptor prevents myocardial fibrosis in spontaneously hypertensive rats.

    Nerea Hermida;Begoña López;Arantxa González;Javier Dotor

  • A Peptide Inhibitor of FOXP3 Impairs Regulatory T Cell Activity and Improves Vaccine Efficacy in Mice

    Noelia Casares;Francesc Rudilla;Laura Arribillaga;Diana Llopiz

  • Enhanced anti-tumor efficacy of checkpoint inhibitors in combination with the histone deacetylase inhibitor Belinostat in a murine hepatocellular carcinoma model

    Diana Llopiz;Marta Ruiz;Lorea Villanueva;Tamara Iglesias

  • The Extra Domain A from Fibronectin Targets Antigens to TLR4-Expressing Cells and Induces Cytotoxic T Cell Responses In Vivo

    Juan J. Lasarte;Noelia Casares;Marta Gorraiz;Sandra Hervás-Stubbs;Sandra Hervás-Stubbs

  • Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade

    Daniel Ajona;Sergio Ortiz-Espinosa;Teresa Lozano;Francisco Exposito

  • Poly(Anhydride) Nanoparticles Act as Active Th1 Adjuvants through Toll-Like Receptor Exploitation

    I. Tamayo;J. M. Irache;C. Mansilla;J. Ochoa-Repáraz

Frequent Co-Authors

Jesús Prieto
Jesús Prieto University of Navarra
Sandra Hervas-Stubbs
Sandra Hervas-Stubbs University of Navarra
Ignacio Melero
Ignacio Melero University of Oxford
Bruno Sangro
Bruno Sangro University of Navarra
Ruben Pio
Ruben Pio University of Navarra
Felipe Prosper
Felipe Prosper University of Navarra
Jonathan L. Heeney
Jonathan L. Heeney University of Cambridge
François Ghiringhelli
François Ghiringhelli Centre Georges François Leclerc
Luis M. Montuenga
Luis M. Montuenga University of Navarra

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