World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
53
Citations
8628
World Ranking
2397
National Ranking
37

Ruben Pio publication distribution in Molecular Biology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Molecular Biology in 2026. The highlighted bar marks where Ruben Pio sits on this spectrum.

47–56 publications: 7 scientists 57–66 publications: 17 scientists 67–76 publications: 65 scientists 77–86 publications: 90 scientists 87–96 publications: 125 scientists 97–106 publications: 131 scientists 107–116 publications: 162 scientists 117–126 publications: 177 scientists 127–136 publications: 158 scientists 137–146 publications: 158 scientists 147–156 publications: 146 scientists 157–166 publications: 159 scientists 167–176 publications: 131 scientists 177–186 publications: 110 scientists 187–196 publications: 112 scientists 197–206 publications: 100 scientists 207–216 publications: 89 scientists 217–226 publications: 98 scientists 227–236 publications: 74 scientists 237–246 publications: 72 scientists 247–256 publications: 63 scientists 257–266 publications: 53 scientists 267–276 publications: 54 scientists 277–286 publications: 49 scientists 287–296 publications: 52 scientists 297–306 publications: 43 scientists 307–316 publications: 46 scientists 317–326 publications: 41 scientists 327–336 publications: 42 scientists 337–346 publications: 31 scientists 347–356 publications: 28 scientists 357–366 publications: 29 scientists 367–376 publications: 26 scientists 377–386 publications: 24 scientists 387–396 publications: 24 scientists 397–406 publications: 14 scientists 407–416 publications: 13 scientists 417–426 publications: 20 scientists 427–436 publications: 12 scientists 437–446 publications: 20 scientists 447–456 publications: 11 scientists 457–466 publications: 10 scientists 467–476 publications: 14 scientists 477–486 publications: 14 scientists 487–496 publications: 10 scientists 497–506 publications: 13 scientists 507–516 publications: 13 scientists 517–526 publications: 2 scientists 527–536 publications: 4 scientists 537–546 publications: 6 scientists 547–556 publications: 8 scientists 557–563 publications: 6 scientists 564+ publications: 100 scientists
47 publications 564+

This scientist: 153 publications — 39th percentile

39% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 564 publications or more.

Ruben Pio D-index placement in Molecular Biology in 2026

The chart shows the D-index (discipline H-index) distribution of Molecular Biology scientists ranked by Research.com in 2026. The highlighted bar marks where Ruben Pio sits on this spectrum.

40–41 D-Index: 36 scientists 42–43 D-Index: 101 scientists 44–45 D-Index: 115 scientists 46–47 D-Index: 121 scientists 48–49 D-Index: 118 scientists 50–51 D-Index: 130 scientists 52–53 D-Index: 106 scientists 54–55 D-Index: 116 scientists 56–57 D-Index: 113 scientists 58–59 D-Index: 129 scientists 60–61 D-Index: 120 scientists 62–63 D-Index: 105 scientists 64–65 D-Index: 131 scientists 66–67 D-Index: 95 scientists 68–69 D-Index: 97 scientists 70–71 D-Index: 106 scientists 72–73 D-Index: 83 scientists 74–75 D-Index: 89 scientists 76–77 D-Index: 77 scientists 78–79 D-Index: 70 scientists 80–81 D-Index: 73 scientists 82–83 D-Index: 60 scientists 84–85 D-Index: 48 scientists 86–87 D-Index: 45 scientists 88–89 D-Index: 50 scientists 90–91 D-Index: 31 scientists 92–93 D-Index: 51 scientists 94–95 D-Index: 43 scientists 96–97 D-Index: 38 scientists 98–99 D-Index: 39 scientists 100–101 D-Index: 41 scientists 102–103 D-Index: 29 scientists 104–105 D-Index: 33 scientists 106–107 D-Index: 35 scientists 108–109 D-Index: 20 scientists 110–111 D-Index: 38 scientists 112–113 D-Index: 19 scientists 114–115 D-Index: 28 scientists 116–117 D-Index: 13 scientists 118–119 D-Index: 23 scientists 120–121 D-Index: 16 scientists 122–123 D-Index: 15 scientists 124–125 D-Index: 11 scientists 126–127 D-Index: 21 scientists 128–129 D-Index: 7 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 14 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 9 scientists 138–139 D-Index: 8 scientists 140–141 D-Index: 16 scientists 142–143 D-Index: 7 scientists 144 D-Index: 7 scientists 145+ D-Index: 100 scientists
40 D-Index 145+

This scientist: 53 D-Index — 24th percentile

24% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 145 D-Index or more.

Overview

Ruben Pio is affiliated with the University of Navarra in Spain and has made significant contributions to the fields of medicine, immunology, and molecular biology. Their research is primarily focused on cancer, with a particular emphasis on lung cancer treatments and mutations, immune system interactions in cancer, and cancer immunotherapy.

Their main fields of study include:

  • Medicine
  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology

Within these broader fields, they have specialized subfields of research that include:

  • Immunology
  • Oncology
  • Molecular Biology
  • Pulmonary and Respiratory Medicine
  • Cancer Research

Themes central to Ruben Pio's work cover diverse topics such as:

  • Lung Cancer Treatments and Mutations
  • Complement system in diseases
  • Immune cells in cancer
  • Cancer Immunotherapy and Biomarkers
  • Cancer Genomics and Diagnostics
  • Immune Cell Function and Interaction
  • RNA modifications and cancer

Ruben Pio has published in multiple journals with a notable presence in venues such as:

  • Annals of Oncology
  • Immunobiology
  • Cancers
  • Frontiers in Immunology
  • Cancer Letters

Frequent co-authors in Ruben Pio's publications include:

  • Daniel Ajona
  • Luis M. Montuenga
  • Yaiza Senent
  • Alfonso Calvo
  • Ana Remírez

Representative publications from Ruben Pio's recent body of work include:

  • "Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade," 2020, Nature Cancer
  • "Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis," 2021, Cancer Letters
  • "SRC family kinase (SFK) inhibitor dasatinib improves the antitumor activity of anti-PD-1 in NSCLC models by inhibiting Treg cell conversion and proliferation," 2021, Journal for ImmunoTherapy of Cancer
  • "Endogenous Retroelement Activation by Epigenetic Therapy Reverses the Warburg Effect and Elicits Mitochondrial-Mediated Cancer Cell Death," 2020, Cancer Discovery
  • "Genome-wide profiling of non-smoking-related lung cancer cells reveals common RB1 rearrangements associated with histopathologic transformation in EGFR-mutant tumors," 2020, Annals of Oncology

Best Publications

  • Biomarkers in Lung Cancer Screening: Achievements, Promises, and Challenges

    Luis M. Seijo;Nir Peled;Daniel Ajona;Mattia Boeri

  • Hypoxia-inducible factor-1 (HIF-1) up-regulates adrenomedullin expression in human tumor cell lines during oxygen deprivation: a possible promotion mechanism of carcinogenesis.

    Mercedes Garayoa;Alfredo Martínez;Sunmin Lee;Rubén Pío

  • Alternative splicing: an emerging topic in molecular and clinical oncology

    María J Pajares;Teresa Ezponda;Raúl Catena;Alfonso Calvo

  • Complement Factor H Is a Serum-binding Protein for Adrenomedullin, and the Resulting Complex Modulates the Bioactivities of Both Partners

    Rubén Pı́o;Alfredo Martı́nez;Edward J. Unsworth;Jeffrey A. Kowalak

  • Anaphylatoxin C5a creates a favorable microenvironment for lung cancer progression.

    Leticia Corrales;Daniel Ajona;Stavros Rafail;Juan J. Lasarte

  • Frequent BRG1/SMARCA4-inactivating mutations in human lung cancer cell lines.

    Pedro P. Medina;Octavio A. Romero;Takashi Kohno;Luis M. Montuenga

  • A Combined PD-1/C5a Blockade Synergistically Protects against Lung Cancer Growth and Metastasis

    Daniel Ajona;Sergio Ortiz-Espinosa;Haritz Moreno;Teresa Lozano

  • The Role of Complement in Tumor Growth

    Ruben Pio;Leticia Corrales;John D. Lambris

  • Altered patterns of expression of members of the heterogeneous nuclear ribonucleoprotein (hnRNP) family in lung cancer

    Irene Pino;Rubén Pı́o;Gemma Toledo;Natalia Zabalegui

  • Complementing the Cancer-Immunity Cycle.

    Ruben Pio;Daniel Ajona;Sergio Ortiz-Espinosa;Alberto Mantovani

  • The Effects of Adrenomedullin Overexpression in Breast Tumor Cells

    Alfredo Martínez;Michele Vos;Liliana Guédez;Gurmeet Kaur

  • Complement inhibition in cancer therapy.

    Ruben Pio;Daniel Ajona;John D. Lambris

  • A gene-alteration profile of human lung cancer cell lines†

    Raquel Blanco;Reika Iwakawa;Moying Tang;Takashi Kohno

  • Novel and natural knockout lung cancer cell lines for the LKB1/STK11 tumor suppressor gene

    Julian Carretero;Pedro P Medina;Ruben Pio;Luis M Montuenga

  • Investigation of Complement Activation Product C4d as a Diagnostic and Prognostic Biomarker for Lung Cancer

    Daniel Ajona;María J. Pajares;Leticia Corrales;Jose L. Perez-Gracia

  • Expression of complement factor H by lung cancer cells: effects on the activation of the alternative pathway of complement.

    Daniel Ajona;Zafira Castaño;Mercedes Garayoa;Enrique Zudaire

  • Down-regulation of human complement factor H sensitizes non-small cell lung cancer cells to complement attack and reduces in vivo tumor growth.

    Daniel Ajona;Yi-Fan Hsu;Leticia Corrales;Luis M. Montuenga

  • Molecular Analysis of a Multistep Lung Cancer Model Induced by Chronic Inflammation Reveals Epigenetic Regulation of p16 and Activation of the DNA Damage Response Pathway

    David Blanco;Silvestre Vicent;Silvestre Vicent;Mario F. Fraga;Ignacio Fernandez-Garcia;Ignacio Fernandez-Garcia

  • A Novel Epigenetic Signature for Early Diagnosis in Lung Cancer.

    Angel Diaz-Lagares;Jesus Mendez-Gonzalez;David Hervas;Maria Saigi

  • Innate immune mediators in cancer: between defense and resistance.

    Pedro Berraondo;Luna Minute;Daniel Ajona;Daniel Ajona;Leticia Corrales

Frequent Co-Authors

Luis M. Montuenga
Luis M. Montuenga University of Navarra
Frank Cuttitta
Frank Cuttitta National Institutes of Health
Carmen Behrens
Carmen Behrens The University of Texas MD Anderson Cancer Center
Ignacio I. Wistuba
Ignacio I. Wistuba The University of Texas MD Anderson Cancer Center
Ignacio Melero
Ignacio Melero University of Oxford
Tom Eirik Mollnes
Tom Eirik Mollnes Oslo University Hospital
John D. Lambris
John D. Lambris University of Pennsylvania
Anna M. Blom
Anna M. Blom Lund University
Juan José Lasarte
Juan José Lasarte University of Navarra
Manel Esteller
Manel Esteller Josep Carreras Leukaemia Research Institute

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