World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
16946
World Ranking
8600
National Ranking
3863

Research.com Recognitions

  • 1960 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Frank Cuttitta is a researcher affiliated with the National Institutes of Health in the United States. Their research spans multiple fields within biomedical science, with a focus on medicine and biochemistry, genetics, and molecular biology.

The scientist's work covers various subfields including molecular biology, oncology, pulmonary and respiratory medicine, cellular and molecular neuroscience, and epidemiology. These areas demonstrate an interdisciplinary approach to understanding complex biological and medical questions.

Key topics addressed in their research include:

  • Cancer cells and metastasis
  • RNA research and splicing
  • Colorectal cancer surgical treatments
  • Occupational and environmental lung diseases
  • Neuropeptides and animal physiology
  • Influenza virus research studies
  • Neuroscience of respiration and sleep

Frank Cuttitta has published recent papers in significant journals. Notable publications are:

  • "Cancer cell survival depends on collagen uptake into tumor-associated stroma," 2022, Nature Communications
  • "Novel neuroendocrine role of γ-aminobutyric acid and gastrin-releasing peptide in the host response to influenza infection," 2023, Mucosal Immunology
  • "Human Cripto-1 and Cripto-3 Protein Expression in Normal and Malignant Settings That Conflicts with Established Conventions," 2024, Cancers
  • "Hyperoxic Lung Injury in Newborn Mice is Abrogated by Neutralizing mAb 2A11 to Gastrin-Releasing Peptide (GRP)," 2020, The FASEB Journal
  • "69P Novel monoclonal antibodies can distinguish Cripto-1 from Cripto-3 proteins: Clinical implications and potential new biomarkers," 2023, Annals of Oncology

Their frequent co-authors reflect active collaboration in their research field. These include Mary E. Sunday, Josune García-Sanmartín, Alfredo Martínez, Yang Feng, and Kuo-Sheng Hsu.

Frank Cuttitta's work has been disseminated in reputable scientific venues such as Nature Communications, Mucosal Immunology, Cancers, The FASEB Journal, and Annals of Oncology.

The scientist has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS) since 1960.

Best Publications

  • Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer.

    Frank Cuttitta;Desmond N. Carney;James Mulshine;Terry W. Moody

  • Determination of the immunoreactive fraction of radiolabeled monoclonal antibodies by linear extrapolation to binding at infinite antigen excess.

    T. Lindmo;E. Boven;F. Cuttitta;J. Fedorko

  • Hsp90 Regulates a von Hippel Lindau-independent Hypoxia-inducible Factor-1α-degradative Pathway

    Jennifer S. Isaacs;Yun-Jin Jung;Edward G. Mimnaugh;Alfredo Martinez

  • Markedly decreased expression of class I histocompatibility antigens, protein, and mRNA in human small-cell lung cancer.

    A Doyle;W J Martin;K Funa;A Gazdar

  • ADRENOMEDULLIN EXPRESSION IN HUMAN TUMOR CELL LINES : ITS POTENTIAL ROLE AS AN AUTOCRINE GROWTH FACTOR

    Mae Jean Miller;Alfredo Martínez;Edward J. Unsworth;Carol J. Thiele

  • Selective stimulation of small cell lung cancer clonal growth by bombesin and gastrin-releasing peptide.

    Desmond N. Carney;Frank Cuttitta;Terry W. Moody;John D. Minna

  • Hypoxia-inducible factor-1 (HIF-1) up-regulates adrenomedullin expression in human tumor cell lines during oxygen deprivation: a possible promotion mechanism of carcinogenesis.

    Mercedes Garayoa;Alfredo Martínez;Sunmin Lee;Rubén Pío

  • Complement Factor H Is a Serum-binding Protein for Adrenomedullin, and the Resulting Complex Modulates the Bioactivities of Both Partners

    Rubén Pı́o;Alfredo Martı́nez;Edward J. Unsworth;Jeffrey A. Kowalak

  • I. High affinity receptors for bombesin/GRP-like peptides on human small cell lung cancer

    Terry W. Moody;Desmond N. Carney;Frank Cuttitta;Keith Quattrocchi

  • Expression of adrenomedullin in normal human lung and in pulmonary tumors.

    Alfredo Martinez;Mae Jean Miller;Edward J. Unsworth;Jill M. Siegfried

  • Insulin-like growth factor-I can mediate autocrine proliferation of human small cell lung cancer cell lines in vitro.

    Y Nakanishi;J L Mulshine;P G Kasprzyk;R B Natale

  • Regulation of insulin secretion and blood glucose metabolism by adrenomedullin

    Alfredo Martínez;Cyprian Weaver;José López;Sam J. Bhathena

  • Expression of the gastrin-releasing peptide gene in human small cell lung cancer. Evidence for alternative processing resulting in three distinct mRNAs.

    E A Sausville;A M Lebacq-Verheyden;E R Spindel;F Cuttitta

  • The aryl hydrocarbon receptor repressor is a putative tumor suppressor gene in multiple human cancers

    Enrique Zudaire;Natalia Cuesta;Vundavalli Murty;Karen Woodson

  • INSULIN-LIKE GROWTH FACTOR EXPRESSION IN HUMAN CANCER CELL LINES

    Kathryn A. Quinn;Anthony M. Treston;Edward J. Unsworth;Mae-Jean Miller

  • Expression of Adrenomedullin and Its Receptor during Embryogenesis Suggests Autocrine or Paracrine Modes of Action

    Luis M. Montuenga;Alfredo Martínez;Mae Jean Miller;Edward J. Unsworth

  • Monoclonal antibodies that demonstrate specificity for several types of human lung cancer.

    Frank Cuttitta;Steven Rosen;Adi F. Gazdar;John D. Minna

  • Adrenomedullin and cancer.

    E Zudaire;A Martı́nez;F Cuttitta

  • [Psi 13,14] bombesin analogues inhibit growth of small cell lung cancerin vitro and in vivo.

    Samira Mahmoud;Julie Staley;John Taylor;Arthur Bogden

  • GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood–brain barrier

    Mike Cullen;Mohammed K. Elzarrad;Steven Seaman;Enrique Zudaire

Frequent Co-Authors

Ruben Pio
Ruben Pio University of Navarra
Luis M. Montuenga
Luis M. Montuenga University of Navarra
John D. Minna
John D. Minna The University of Texas Southwestern Medical Center
Terry W. Moody
Terry W. Moody National Institutes of Health
Adi F. Gazdar
Adi F. Gazdar The University of Texas Southwestern Medical Center
David S. Salomon
David S. Salomon National Institutes of Health
J.M. Polak
J.M. Polak Hammersmith Hospital
William G. Stetler-Stevenson
William G. Stetler-Stevenson National Institutes of Health
Jane B. Trepel
Jane B. Trepel National Institutes of Health
Tom Walsh
Tom Walsh University of Washington

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