D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 55 Citations 14,009 136 World Ranking 7447 National Ranking 3388

Research.com Recognitions

Awards & Achievements

1960 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • DNA

His scientific interests lie mostly in Molecular biology, Receptor, Adrenomedullin, Autocrine signalling and Internal medicine. His studies deal with areas such as Insulin-like growth factor, RNA, Peptide sequence, Antibody and Binding site as well as Molecular biology. His Receptor study combines topics in areas such as Cell and In situ hybridization.

His Adrenomedullin research is multidisciplinary, incorporating perspectives in Immunocytochemistry, Pathology, Factor H, Carcinogenesis and Cell biology. His study in Autocrine signalling is interdisciplinary in nature, drawing from both Gene expression, Growth factor and Paracrine signalling. His Internal medicine research includes elements of Endocrinology and Western blot.

His most cited work include:

  • Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer. (1247 citations)
  • Determination of the immunoreactive fraction of radiolabeled monoclonal antibodies by linear extrapolation to binding at infinite antigen excess. (804 citations)
  • Hsp90 Regulates a von Hippel Lindau-independent Hypoxia-inducible Factor-1α-degradative Pathway (545 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Internal medicine, Adrenomedullin, Molecular biology, Endocrinology and Cancer research. Internal medicine connects with themes related to Oncology in his study. Frank Cuttitta combines subjects such as Carcinogenesis, Binding protein, Factor H and Cell biology with his study of Adrenomedullin.

He combines subjects such as Cell culture, Cell, Biochemistry and Antibody, Monoclonal antibody with his study of Molecular biology. His research investigates the link between Endocrinology and topics such as Receptor that cross with problems in In situ hybridization. His Cancer research research includes elements of Cancer, Growth factor, Cell growth and In vivo.

He most often published in these fields:

  • Internal medicine (33.33%)
  • Adrenomedullin (30.88%)
  • Molecular biology (30.39%)

What were the highlights of his more recent work (between 2004-2020)?

  • Angiogenesis (10.78%)
  • Cancer research (18.14%)
  • Gastrin-releasing peptide (14.71%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Angiogenesis, Cancer research, Gastrin-releasing peptide, Adrenomedullin and Internal medicine. His Cancer research research also works with subjects such as

  • Cell growth, which have a strong connection to Endothelial stem cell, Molecular biology, Oncogene and Sulforaphane,
  • Carcinogenesis that intertwine with fields like Carcinogen,
  • Pathology which is related to area like Cell culture and Lung injury,
  • Immune system which connect with Apoptosis. Gastrin-releasing peptide is a subfield of Receptor that Frank Cuttitta tackles.

His work deals with themes such as Cancer, Function, Gene, Disease and Biological activity, which intersect with Adrenomedullin. His Internal medicine study combines topics in areas such as Endocrinology and Oncology. In his research, Combinatorial chemistry is intimately related to Small molecule, which falls under the overarching field of Endocrinology.

Between 2004 and 2020, his most popular works were:

  • The aryl hydrocarbon receptor repressor is a putative tumor suppressor gene in multiple human cancers (165 citations)
  • GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood–brain barrier (131 citations)
  • Abnormal lymphangiogenesis in idiopathic pulmonary fibrosis with insights into cellular and molecular mechanisms (85 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • DNA

Immunology, Cancer research, Angiogenesis, Endocrinology and Internal medicine are his primary areas of study. His study in Immunology is interdisciplinary in nature, drawing from both Progenitor cell, Embryonic stem cell and Bronchoalveolar lavage, Lung. His Cancer research research is multidisciplinary, incorporating elements of Cell growth, Transcription factor, Mammary gland morphogenesis, Mammary gland and Myoepithelial cell.

His Angiogenesis research integrates issues from Blood–brain barrier, Gastrin-releasing peptide, Intensive care, Receptor and In vivo. He has included themes like Carcinogenesis, Cancer, Tumor promotion and Adrenomedullin in his Endocrinology study. His Internal medicine study frequently intersects with other fields, such as Biological activity.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer.

Frank Cuttitta;Desmond N. Carney;James Mulshine;Terry W. Moody.
Nature (1985)

1628 Citations

Determination of the immunoreactive fraction of radiolabeled monoclonal antibodies by linear extrapolation to binding at infinite antigen excess.

T. Lindmo;E. Boven;F. Cuttitta;J. Fedorko.
Journal of Immunological Methods (1984)

1067 Citations

Hsp90 Regulates a von Hippel Lindau-independent Hypoxia-inducible Factor-1α-degradative Pathway

Jennifer S. Isaacs;Yun-Jin Jung;Edward G. Mimnaugh;Alfredo Martinez.
Journal of Biological Chemistry (2002)

834 Citations

ADRENOMEDULLIN EXPRESSION IN HUMAN TUMOR CELL LINES : ITS POTENTIAL ROLE AS AN AUTOCRINE GROWTH FACTOR

Mae Jean Miller;Alfredo Martínez;Edward J. Unsworth;Carol J. Thiele.
Journal of Biological Chemistry (1996)

403 Citations

Markedly decreased expression of class I histocompatibility antigens, protein, and mRNA in human small-cell lung cancer.

A Doyle;W J Martin;K Funa;A Gazdar.
Journal of Experimental Medicine (1985)

383 Citations

Selective stimulation of small cell lung cancer clonal growth by bombesin and gastrin-releasing peptide.

Desmond N. Carney;Frank Cuttitta;Terry W. Moody;John D. Minna.
Cancer Research (1987)

363 Citations

I. High affinity receptors for bombesin/GRP-like peptides on human small cell lung cancer

Terry W. Moody;Desmond N. Carney;Frank Cuttitta;Keith Quattrocchi.
Life Sciences (1985)

345 Citations

Hypoxia-inducible factor-1 (HIF-1) up-regulates adrenomedullin expression in human tumor cell lines during oxygen deprivation: a possible promotion mechanism of carcinogenesis.

Mercedes Garayoa;Mercedes Garayoa;Alfredo Martínez;Sunmin Lee;Rubén Pío.
Molecular Endocrinology (2000)

318 Citations

Expression of adrenomedullin in normal human lung and in pulmonary tumors.

Alfredo Martinez;Mae Jean Miller;Edward J. Unsworth;Jill M. Siegfried.
Endocrinology (1995)

299 Citations

Complement Factor H Is a Serum-binding Protein for Adrenomedullin, and the Resulting Complex Modulates the Bioactivities of Both Partners

Rubén Pı́o;Alfredo Martı́nez;Edward J. Unsworth;Jeffrey A. Kowalak.
Journal of Biological Chemistry (2001)

296 Citations

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