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Frances M. Sladek

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
11651
World Ranking
15540
National Ranking
6482

Frances M. Sladek publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Frances M. Sladek sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 103 publications — 6th percentile

6% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Frances M. Sladek D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Frances M. Sladek sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 54 D-Index — 22nd percentile

22% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Frances M. Sladek is affiliated with the University of California, Riverside in the United States. Their research spans various domains within medicine and biochemistry, genetics, and molecular biology. The scientist has contributed extensively to studies involving liver disease diagnosis and treatment, diet and metabolism, gut microbiota and health, pancreatic function and diabetes, as well as cancer-related topics linking metabolism and hypoxia.

The main fields of study associated with their work include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these broader fields, more specific subfields addressed in their publications are:

  • Molecular Biology
  • Epidemiology
  • Physiology
  • Surgery
  • Cancer Research

The key research topics covered by Frances M. Sladek are:

  • Liver Disease Diagnosis and Treatment
  • Diet and metabolism studies
  • Gut microbiota and health
  • Pancreatic function and diabetes
  • Diet, Metabolism, and Disease
  • Metabolism, Diabetes, and Cancer
  • Cancer, Hypoxia, and Metabolism

Frances M. Sladek has coauthored numerous papers with frequent collaborators including Poonamjot Deol, Sarah H. Radi, Jonathan Deans, Paul Ruegger, and James Borneman.

They have published multiple articles in notable venues, with the most frequent publication outlets being:

  • Frontiers in Endocrinology
  • IUPHAR/BPS Guide to Pharmacology CITE
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Letters
  • Gut Microbes

Selected recent papers by Frances M. Sladek include:

  • "Palmitic acid negatively regulates tumor suppressor PTEN through T366 phosphorylation and protein degradation," 2020, Cancer Letters
  • "Diet high in linoleic acid dysregulates the intestinal endocannabinoid system and increases susceptibility to colitis in Mice," 2023, Gut Microbes
  • "Multiple roles and regulatory mechanisms of the transcription factor HNF4 in the intestine," 2023, Frontiers in Endocrinology
  • "Dysregulation of Hypothalamic Gene Expression and the Oxytocinergic System by Soybean Oil Diets in Male Mice," 2020, Endocrinology
  • "HNF4α isoforms: the fraternal twin master regulators of liver function," 2023, Frontiers in Endocrinology

Best Publications

  • Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily.

    F M Sladek;W M Zhong;E Lai;J E Darnell

  • A unified nomenclature system for the nuclear receptor superfamily

    J. Auwerx;E. Baulieu;M. Beato;M. Becker-Andre

  • A transcriptional hierarchy involved in mammalian cell-type specification.

    Calvin J. Kuo;Pamela B. Conley;Lei Chen;Frances M. Sladek

  • Prevalence of the initiator over the TATA box in human and yeast genes and identification of DNA motifs enriched in human TATA-less core promoters.

    Chuhu Yang;Eugene Bolotin;Tao Jiang;Frances M. Sladek

  • Antagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells.

    M Mietus-Snyder;FM Sladek;GS Ginsburg;CF Kuo

  • Direct G Protein Modulation of Cav2 Calcium Channels

    H. William Tedford;Gerald W. Zamponi

  • Hepatocyte nuclear factor 4α orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver

    Michele A. Battle;Genevieve Konopka;Fereshteh Parviz;Alexandra Lerch Gaggl

  • The orphan receptors COUP-TF and HNF-4 serve as accessory factors required for induction of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids.

    Robert K. Hall;Frances M. Sladek;Daryl K. Granner

  • International Union of Pharmacology. LXVI. Orphan Nuclear Receptors

    Gérard Benoit;Austin Cooney;Vincent Giguere;Holly Ingraham

  • Exclusive Homodimerization of the Orphan Receptor Hepatocyte Nuclear Factor 4 Defines a New Subclass of Nuclear Receptors

    Guoqiang Jiang;Luviminda Nepomuceno;K. Hopkins;F. M. Sladek

  • Identification of an endogenous ligand bound to a native orphan nuclear receptor.

    Xiaohui Yuan;Tuong Chi Ta;Min Lin;Jane R. Evans

  • AMP-Activated Protein Kinase Is Involved in Endothelial NO Synthase Activation in Response to Shear Stress

    Yingjia Zhang;Tzong Shyuan Lee;Erik M. Kolb;Kai Sun

  • The different tissue transcription patterns of genes for HNF-1, C/EBP, HNF-3, and HNF-4, protein factors that govern liver-specific transcription.

    Kleanthis G. Xanthopoulos;Vincent R. Prezioso;William S. Chen;Frances M. Sladek

  • Hepatocyte Nuclear Factor 4α Is Essential for Embryonic Development of the Mouse Colon

    Wendy D. Garrison;Michele A. Battle;Chuhu Yang;Klaus H. Kaestner

  • MAP kinase phosphorylation-dependent activation of Elk-1 leads to activation of the co-activator p300

    Qi Jing Li;Shen Hsi Yang;Yutaka Maeda;Frances M. Sladek

  • Hepatocyte Nuclear Factor-4α Is Essential for Glucose-stimulated Insulin Secretion by Pancreatic β-Cells

    Atsuko Miura;Kazuya Yamagata;Masafumi Kakei;Hiroyasu Hatakeyama

  • Integrated approach for the identification of human hepatocyte nuclear factor 4α target genes using protein binding microarrays

    Eugene Bolotin;Hailing Liao;Tuong Chi Ta;Chuhu Yang

  • What are nuclear receptor ligands

    Frances M. Sladek

  • Hepatocyte Nuclear Factor 4α

    Frances M. Sladek;Shawn D. Seidel

  • Modulation of Transcriptional Activation and Coactivator Interaction by a Splicing Variation in the F Domain of Nuclear Receptor Hepatocyte Nuclear Factor 4α1

    Frances M. Sladek;Michael D. Ruse;Luviminda Nepomuceno;Shih-Ming Huang

Frequent Co-Authors

Peggy J. Farnham
Peggy J. Farnham University of Southern California
Sylvie Mader
Sylvie Mader University of Montreal
Kathleen J. Millen
Kathleen J. Millen Seattle Children's Hospital
Robert F. Hevner
Robert F. Hevner University of California, San Diego
Paola Bovolenta
Paola Bovolenta Spanish National Research Council
Bruce E. Torbett
Bruce E. Torbett Seattle Children's Hospital
Elizabeth M. Simpson
Elizabeth M. Simpson University of British Columbia
Wyeth W. Wasserman
Wyeth W. Wasserman University of British Columbia
Reiner A. Veitia
Reiner A. Veitia Université Paris Cité
Alison H. Banham
Alison H. Banham University of Oxford

External Links

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Exploring these online degree options can provide clear pathways from studies in Biology and Biochemistry to rewarding careers in healthcare and the life sciences.

Best Scientists Citing Frances M. Sladek

Walter Wahli

Walter Wahli

University of Lausanne

Publications: 56

Frank J. Gonzalez

Frank J. Gonzalez

National Institutes of Health

Publications: 48

Vincent Laudet

Vincent Laudet

Okinawa Institute of Science and Technology

Publications: 46

Klaus H. Kaestner

Klaus H. Kaestner

University of Pennsylvania

Publications: 28

Daryl K. Granner

Daryl K. Granner

Vanderbilt University

Publications: 27

Liliane Michalik

Liliane Michalik

University of Lausanne

Publications: 26

Béatrice Desvergne

Béatrice Desvergne

University of Lausanne

Publications: 24

Bart Staels

Bart Staels

University of Lille

Publications: 22

Ronald M. Evans

Ronald M. Evans

Salk Institute for Biological Studies

Publications: 20

Carsten Carlberg

Carsten Carlberg

University of Eastern Finland

Publications: 20

Mary C. Weiss

Mary C. Weiss

Institut Pasteur

Publications: 20

Ken-ichirou Morohashi

Ken-ichirou Morohashi

Kyushu University

Publications: 20

Jan-Åke Gustafsson

Jan-Åke Gustafsson

University of Houston

Publications: 20

Robert H. Costa

Robert H. Costa

University of Illinois at Chicago

Publications: 18

John Y. L. Chiang

John Y. L. Chiang

Northeast Ohio Medical University

Publications: 17

Frédéric P. Lemaigre

Frédéric P. Lemaigre

Université Catholique de Louvain

Publications: 17

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