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D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
14603
World Ranking
17845
National Ranking
622

Overview

Sylvie Mader is affiliated with the University of Montreal in Canada and conducts research primarily in the fields of biochemistry, genetics, molecular biology, and medicine. Their work spans several key subfields including cancer research, genetics, cellular and molecular neuroscience, immunology, and molecular biology.

The scientist's research encompasses a range of topics that include:

  • Estrogen and related hormone effects
  • Nuclear receptors and signaling
  • Macrophage migration inhibitory factor
  • Cancer, lipids, and metabolism
  • Cancer, hypoxia, and metabolism
  • Organic chemistry cycloaddition reactions
  • Apelin-related biomedical research

Mader has contributed to multiple publication venues, with research appearing mainly in:

  • Journal of the Endocrine Society
  • Cells
  • Journal of Molecular Biology
  • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  • Cellular and Molecular Biology

The scientist's recent publications include:

  • Cholesterol as an Endogenous Ligand of ERRα Promotes ERRα-Mediated Cellular Proliferation and Metabolic Target Gene Expression in Breast Cancer Cells, 2020, Cells
  • Minireview: What is Known about SUMOylation Among NR4A Family Members?, 2021, Journal of Molecular Biology
  • Complex regulation of orphan nuclear receptor Nur77 (Nr4a1) transcriptional activity by SUMO2 and PIASγ, 2020, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  • Estrogens desensitize MCF-7 breast cancer cells to apelin-induced autophagy and enhanced growth under estrogen starvation: a possible implication in endocrine resistance, 2022, Cellular and Molecular Biology
  • Design, synthesis and antiproliferative activity of raloxifene/histone deacetylase inhibitor hybrids in breast cancer, 2024, European Journal of Medicinal Chemistry

Frequent co-authors collaborating with Mader include:

  • Fatéma Dodat
  • Daniel Lévesque
  • Amandine Vallet
  • Marine Diennet
  • Sandra Weber

Best Publications

  • Cutting Edge: 1,25-dihydroxyvitamin D3 Is a Direct Inducer of Antimicrobial Peptide Gene Expression

    Tian Tian Wang;Frederick P. Nestel;Véronique Bourdeau;Yoshihiko Nagai

  • Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently

    Mark Leid;Mark Leid;Philippe Kastner;Philippe Kastner;Ruth Lyons;Ruth Lyons;Harikrishna Nakshatri;Harikrishna Nakshatri

  • The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins.

    S. Mader;Han Lee;A. Pause;N. Sonenberg

  • Repression of cap-dependent translation by 4E-binding protein 1: competition with p220 for binding to eukaryotic initiation factor-4E.

    A. Haghighat;S. Mader;A. Pause;N. Sonenberg

  • Large-scale in silico and microarray-based identification of direct 1,25-dihydroxyvitamin D3 target genes.

    Tian-Tian Wang;Luz Elisa Tavera-Mendoza;David Laperriere;Eric Libby

  • Three amino acids of the oestrogen receptor are essential to its ability to distinguish an oestrogen from a glucocorticoid-responsive element.

    Sylvie Mader;Vijay Kumar;Vijay Kumar;Hubert de Verneuil;Pierre Chambon

  • Direct and Indirect Induction by 1,25-Dihydroxyvitamin D3 of the NOD2/CARD15-Defensin β2 Innate Immune Pathway Defective in Crohn Disease

    Tian-Tian Wang;Basel Dabbas;David Laperriere;Ari J. Bitton

  • Negative regulation of the rat stromelysin gene promoter by retinoic acid is mediated by an AP1 binding site.

    R. C. Nicholson;S. Mader;Sunil Nagpal;M. Leid

  • Genome-wide identification of high-affinity estrogen response elements in human and mouse.

    Véronique Bourdeau;Julie Deschênes;Raphaël Métivier;Yoshihiko Nagai

  • Heregulin selectively upregulates vascular endothelial growth factor secretion in cancer cells and stimulates angiogenesis.

    Lily Yen;Xiao-Li You;Ala-Eddin Al Moustafa;Gerald Batist

  • Ligand-Dependent Nuclear Receptor Corepressor LCoR Functions by Histone Deacetylase-Dependent and -Independent Mechanisms

    Isabelle Fernandes;Yolande Bastien;Timothy Wai;Karen Nygard

  • The patterns of binding of RAR, RXR and TR homo- and heterodimers to direct repeats are dictated by the binding specificites of the DNA binding domains.

    S. Mader;Jia-Yang Chen;Z. Chen;J. White

  • Diversity in the mechanisms of gene regulation by estrogen receptors

    Rocio Sanchez;Denis Nguyen;Walter Rocha;John H. White

  • MHC class I–associated peptides derive from selective regions of the human genome

    Hillary Pearson;Tariq Daouda;Diana Paola Granados;Chantal Durette

  • Multiple parameters control the selectivity of nuclear receptors for their response elements. Selectivity and promiscuity in response element recognition by retinoic acid receptors and retinoid X receptors.

    S. Mader;P. Leroy;Jia-Yang Chen;P. Chambon

  • Cell-specific activity of a GGTCA half-palindromic oestrogen-responsive element in the chicken ovalbumin gene promoter.

    L. Tora;M. P. Gaub;S. Mader;A. Dierich

  • Glutathione depletion overcomes resistance to arsenic trioxide in arsenic-resistant cell lines.

    K Davison;S Côté;S Mader;W H Miller

  • Defining a minimal estrogen receptor DNA binding domain.

    Sylvie Mader;Pierre Chambon;John H. White

  • Mechanisms of primary and secondary estrogen target gene regulation in breast cancer cells

    Véronique Bourdeau;Julie Deschênes;David Laperrière;Malika Aid

  • The late retinoic acid induction of laminin B1 gene transcription involves RAR binding to the responsive element.

    G. Vasios;S. Mader;J. D. Gold;M. Leid

Frequent Co-Authors

John H. White
John H. White McGill University
Peggy J. Farnham
Peggy J. Farnham University of Southern California
Kathleen J. Millen
Kathleen J. Millen Seattle Children's Hospital
Robert F. Hevner
Robert F. Hevner University of California, San Diego
Paola Bovolenta
Paola Bovolenta Spanish National Research Council
Bruce E. Torbett
Bruce E. Torbett Seattle Children's Hospital
Elizabeth M. Simpson
Elizabeth M. Simpson University of British Columbia
Wyeth W. Wasserman
Wyeth W. Wasserman University of British Columbia
Reiner A. Veitia
Reiner A. Veitia Université Paris Cité
Alison H. Banham
Alison H. Banham University of Oxford

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