World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
75
Citations
23441
World Ranking
5255
National Ranking
2500

Karl Drlica publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Karl Drlica sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 210 publications — 54th percentile

54% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Karl Drlica D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Karl Drlica sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 75 D-Index — 74th percentile

74% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Karl Drlica is affiliated with Rutgers, The State University of New Jersey in the United States. Their research focuses primarily on topics related to antibiotic resistance, bacterial genetics, and infectious diseases, with significant contributions to the understanding of bacterial death pathways and antimicrobial resistance mechanisms.

The main fields of study associated with Karl Drlica include Biochemistry, Genetics and Molecular Biology, and Medicine. Within these fields, subfields of particular interest are Molecular Biology, Infectious Diseases, Molecular Medicine, Genetics, and Materials Chemistry.

Karl Drlica's work encompasses a range of main topics, such as:

  • Antibiotic Resistance in Bacteria
  • Tuberculosis Research and Epidemiology
  • Bacterial Genetics and Biotechnology
  • Antimicrobial Resistance in Staphylococcus
  • Bacterial biofilms and quorum sensing
  • Enzyme Structure and Function
  • RNA and protein synthesis mechanisms

They have published multiple papers in various scientific venues, with frequent publications in bioRxiv (Cold Spring Harbor Laboratory), Proceedings of the National Academy of Sciences, mBio, Antimicrobial Agents and Chemotherapy, and eLife.

Representative recent publications include:

  • "A broadly applicable, stress-mediated bacterial death pathway regulated by the phosphotransferase system (PTS) and the cAMP-Crp cascade," 2022, Proceedings of the National Academy of Sciences
  • "Glutamine Is Required for M1-like Polarization of Macrophages in Response to Mycobacterium tuberculosis Infection," 2022, mBio
  • "Bacterial death from treatment with fluoroquinolones and other lethal stressors," 2020, Expert Review of Anti-infective Therapy
  • "Moxifloxacin-Mediated Killing of Mycobacterium tuberculosis Involves Respiratory Downshift, Reductive Stress, and Accumulation of Reactive Oxygen Species," 2022, Antimicrobial Agents and Chemotherapy
  • "Quorum-sensing agr system of Staphylococcus aureus primes gene expression for protection from lethal oxidative stress," 2023, eLife

Karl Drlica collaborates regularly with several coauthors, including:

  • Xilin Zhao
  • Alejandro Pironti
  • Bo Shopsin
  • Gregory Putzel
  • Robert J. Ulrich

Best Publications

  • DNA gyrase, topoisomerase IV, and the 4-quinolones.

    Karl Drlica;Xilin Zhao

  • Histonelike proteins of bacteria.

    K Drlica;J Rouviere-Yaniv

  • Quinolone-mediated bacterial death.

    Karl Drlica;Muhammad Malik;Robert J. Kerns;Xilin Zhao

  • Restricting the Selection of Antibiotic-Resistant Mutants: A General Strategy Derived from Fluoroquinolone Studies

    Xilin Zhao;Karl Drlica

  • The mutant selection window and antimicrobial resistance

    Karl Drlica

  • Escherichia coli DNA topoisomerase I mutants: Increased supercoiling is corrected by mutations near gyrase genes

    Gail J. Pruss;Stephen H. Manes;Karl Drlica

  • Control of bacterial DNA supercoiling

    Karl Drlica

  • Post-stress bacterial cell death mediated by reactive oxygen species

    Yuzhi Hong;Jie Zeng;Xiuhong Wang;Xiuhong Wang;Karl Drlica

  • Inhibitors of DNA topoisomerases

    Karl Drlica;Robert J. Franco

  • Reactive oxygen species and the bacterial response to lethal stress.

    Xilin Zhao;Xilin Zhao;Karl Drlica

  • Mutant selection window hypothesis updated.

    Karl Drlica;Xilin Zhao

  • DNA supercoiling and prokaryotic transcription

    Gail J. Pruss;Karl Drlica;Karl Drlica

  • Quinolones: Action and Resistance Updated

    Karl Drlica;Hiroshi Hiasa;Robert Kerns;Muhammad Malik

  • Mechanism of fluoroquinolone action.

    Karl Drlica

  • Mutant Prevention Concentrations of Fluoroquinolones for Clinical Isolates of Streptococcus pneumoniae

    Joseph M. Blondeau;Xilin Zhao;Glen Hansen;Karl Drlica

  • Biology of bacterial deoxyribonucleic acid topoisomerases.

    K Drlica

  • FLUOROQUINOLONES: ACTION AND RESISTANCE

    Karl Drlica;Muhammad Malik

  • Effect of fluoroquinolone concentration on selection of resistant mutants of Mycobacterium bovis BCG and Staphylococcus aureus.

    Yuzhi Dong;Xilin Zhao;John Domagala;Karl Drlica

  • DNA gyrase and topoisomerase IV on the bacterial chromosome: quinolone-induced DNA cleavage.

    Chang-Rung Chen;Muhammad Malik;Muhammad Malik;Michael Snyder;Michael Snyder;Karl Drlica;Karl Drlica

  • Restricting the selection of antibiotic-resistant mutant bacteria: measurement and potential use of the mutant selection window.

    Xilin Zhao;Karl Drlica

Frequent Co-Authors

Xilin Zhao
Xilin Zhao Xiamen University
Abraham Pinter
Abraham Pinter Rutgers, The State University of New Jersey
Barry N. Kreiswirth
Barry N. Kreiswirth Center for Discovery and Innovation
James J. Rahal
James J. Rahal New York Hospital Queens
Michael Snyder
Michael Snyder Stanford University
James M. Musser
James M. Musser Houston Methodist
James M. Berger
James M. Berger Johns Hopkins University
Fred Russell Kramer
Fred Russell Kramer Rutgers, The State University of New Jersey
Yogendra Singh
Yogendra Singh University of Delhi
Srinand Sreevatsan
Srinand Sreevatsan Michigan State University

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