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Biology and Biochemistry

D-Index
57
Citations
19532
World Ranking
13549
National Ranking
5744

Overview

Steven J. Fliesler is affiliated with the University at Buffalo, State University of New York in the United States. Their research spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a particular focus on Molecular Biology, Ophthalmology, Cell Biology, Surgery, and Neurology.

Their work centers on several main topics including:

  • Retinal Development and Disorders
  • Retinal Diseases and Treatments
  • Cholesterol and Lipid Metabolism
  • Peroxisome Proliferator-Activated Receptors
  • Retinoids in leukemia and cellular processes
  • Cellular transport and secretion
  • Traumatic Brain Injury and Neurovascular Disturbances

Fliesler has frequently published in the following venues:

  • Experimental Eye Research
  • Journal of Lipid Research
  • International Journal of Molecular Sciences
  • Preprints.org
  • Cells

Their recent publications include:

  • "Reducing acetylated tau is neuroprotective in brain injury" (2021, Cell)
  • "Cholesterol homeostasis in the vertebrate retina: biology and pathobiology" (2020, Journal of Lipid Research)
  • "Functional Peroxisomes Are Essential for Efficient Cholesterol Sensing and Synthesis" (2020, Frontiers in Cell and Developmental Biology)
  • "An inducible Cre mouse for studying roles of the RPE in retinal physiology and disease" (2021, JCI Insight)
  • "Reassessing the suitability of ARPE-19 cells as a valid model of native RPE biology" (2022, Experimental Eye Research)

Among their frequent collaborators are:

  • Sriganesh Ramachandra Rao
  • Steven J. Pittler
  • Mai Nguyen
  • Lara A. Skelton
  • Agnieszka Onyśk

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Chemistry and metabolism of lipids in the vertebrate retina

    S J Fliesler;R E Anderson

  • Intraretinal lipid transport is dependent on high density lipoprotein-like particles and class B scavenger receptors.

    Nomingerel Tserentsoodol;Natalyia V. Gordiyenko;Iranzu Pascual;Jung Wha Lee

  • Reducing acetylated tau is neuroprotective in brain injury.

    Min Kyoo Shin;Min Kyoo Shin;Edwin Vázquez-Rosa;Edwin Vázquez-Rosa;Yeojung Koh;Yeojung Koh;Matasha Dhar;Matasha Dhar

  • Long-term and age-dependent restoration of visual function in a mouse model of CNGB3-associated achromatopsia following gene therapy

    Livia S Carvalho;Jianhua Xu;Rachael A Pearson;Alexander J Smith

  • Uptake of cholesterol by the retina occurs primarily via a low density lipoprotein receptor-mediated process.

    Nomingerel Tserentsoodol;Jorge Sztein;Mercedes Campos;Natalya V Gordiyenko

  • Intravitreal Vancomycin: Retinal Toxicity, Clearance, and Interaction With Gentamicin

    Stephen C. Pflugfelder;Eleut Hernández;Steven J. Fliesler;Juana Alvarez

  • The relationship between opsin overexpression and photoreceptor degeneration.

    Elaine Tan;Quan Wang;Alexander B. Quiambao;Xiaoping Xu

  • The ins and outs of cholesterol in the vertebrate retina

    Steven J. Fliesler;Lionel Bretillon

  • Gene delivery to mitotic and postmitotic photoreceptors via compacted DNA nanoparticles results in improved phenotype in a mouse model of retinitis pigmentosa

    Xue Cai;Shannon M. Conley;Zack Nash;Steven J. Fliesler;Steven J. Fliesler

  • Endoplasmic Reticulum Stress and the Unfolded Protein Responses in Retinal Degeneration

    Sarah X. Zhang;Emily Sanders;Steven J. Fliesler;Joshua J. Wang

  • Onecut1 and Onecut2 redundantly regulate early retinal cell fates during development

    Darshan Sapkota;Hemabindu Chintala;Fuguo Wu;Steven J. Fliesler

  • Formation of 7-dehydrocholesterol-containing membrane rafts in vitro and in vivo, with relevance to the Smith-Lemli-Opitz syndrome

    R. Kennedy Keller;Thomas Paul Arnold;Steven j. Fliesler

  • Membrane morphogenesis in retinal rod outer segments: inhibition by tunicamycin.

    S J Fliesler;M E Rayborn;J G Hollyfield

  • A Partial Structural and Functional Rescue of a Retinitis Pigmentosa Model with Compacted DNA Nanoparticles

    Xue Cai;Zack Nash;Shannon M. Conley;Steven J. Fliesler

  • Cholesterol suppresses cellular TGF-β responsiveness: implications in atherogenesis

    Chun-Lin Chen;I-Hua Liu;Steven J. Fliesler;Xianlin Han

  • Mechanism of aminobisphosphonate action: characterization of alendronate inhibition of the isoprenoid pathway.

    R.Kennedy Keller;Steven J. Fliesler

  • The Cys214-->Ser mutation in peripherin/rds causes a loss-of-function phenotype in transgenic mice.

    Heidi M. Stricker;Xi-Qin Ding;Alexander Quiambao;Steven J. Fliesler

  • Retention of function without normal disc morphogenesis occurs in cone but not rod photoreceptors

    Rafal Farjo;Jeff S. Skaggs;Barbara A. Nagel;Alexander B. Quiambao

  • The R172W mutation in peripherin/rds causes a cone–rod dystrophy in transgenic mice

    Xi-Qin Ding;May Nour;Linda M. Ritter;Andrew F.X. Goldberg

Frequent Co-Authors

Neal S. Peachey
Neal S. Peachey Cleveland Clinic
Machelle T. Pardue
Machelle T. Pardue Georgia Institute of Technology
Ned A. Porter
Ned A. Porter Vanderbilt University
Joe G. Hollyfield
Joe G. Hollyfield Baylor College of Medicine
Robert E. Anderson
Robert E. Anderson University of Oklahoma Health Sciences Center
Peter D. Lukasiewicz
Peter D. Lukasiewicz Washington University in St. Louis
Allen Taylor
Allen Taylor Tufts University
Feixiong Cheng
Feixiong Cheng Case Western Reserve University
Forbes D. Porter
Forbes D. Porter National Institutes of Health
Dana C. Crawford
Dana C. Crawford Case Western Reserve University

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