What is he best known for?
The fields of study he is best known for:
His scientific interests lie mostly in Molecular biology, Retina, Biochemistry, Cell biology and Retinitis pigmentosa.
His Molecular biology research is multidisciplinary, relying on both Retinal degeneration, Retinal, Transgene, Mutation and Opsin.
His study looks at the relationship between Retinal degeneration and topics such as Gene expression, which overlap with Electroretinography.
His work on Retinal Cone Photoreceptor Cells, Retinal pigment epithelium and Interphotoreceptor matrix as part of general Retina research is often related to Retinol binding protein, thus linking different fields of science.
His work on Tunicamycin, Sterol, Enzyme and Cholesterol is typically connected to Smith–Lemli–Opitz syndrome as part of general Biochemistry study, connecting several disciplines of science.
His Cell biology research incorporates themes from Retinal Rod Photoreceptor Cells, Cell fate determination and Lipid biosynthesis.
His most cited work include:
- Intraretinal lipid transport is dependent on high density lipoprotein-like particles and class B scavenger receptors. (151 citations)
- The relationship between opsin overexpression and photoreceptor degeneration. (134 citations)
- Long-term and age-dependent restoration of visual function in a mouse model of CNGB3-associated achromatopsia following gene therapy (132 citations)
What are the main themes of his work throughout his whole career to date?
Steven J. Fliesler spends much of his time researching Retinal, Retina, Cell biology, Biochemistry and Retinal degeneration.
The concepts of his Retinal study are interwoven with issues in Molecular biology and Tunicamycin.
His work carried out in the field of Retina brings together such families of science as Internal medicine, Anatomy, Endocrinology and Western blot.
His Cell biology study combines topics in areas such as Peripherin 2, Cell type, Visual phototransduction and Glycoprotein.
His Retinal degeneration research includes themes of Haploinsufficiency, Retinal Cone Photoreceptor Cells and Retinitis pigmentosa.
His study in Cholesterol is interdisciplinary in nature, drawing from both Squalene and Reductase.
He most often published in these fields:
- Retinal (31.15%)
- Retina (32.38%)
- Cell biology (29.51%)
What were the highlights of his more recent work (between 2014-2021)?
- Cell biology (29.51%)
- Retina (32.38%)
- Smith–Lemli–Opitz syndrome (23.36%)
In recent papers he was focusing on the following fields of study:
Steven J. Fliesler mainly investigates Cell biology, Retina, Smith–Lemli–Opitz syndrome, Retinal and Retinal degeneration.
His Cell biology study combines topics from a wide range of disciplines, such as Retinal pigment epithelium, Cell culture, Genetically modified mouse and Sterol.
His research in Retina intersects with topics in Simvastatin, Endocrinology, Central nervous system, Internal medicine and Epigenetics.
Many of his research projects under Endocrinology are closely connected to Glucose homeostasis with Glucose homeostasis, tying the diverse disciplines of science together.
His Retinal study is concerned with Biochemistry in general.
His study on Retinal degeneration also encompasses disciplines like
- Retinitis pigmentosa which intersects with area such as Dehydrodolichyl diphosphate synthase,
- Electroretinography most often made with reference to Cell type.
Between 2014 and 2021, his most popular works were:
- The Unfolded Protein Response in Retinal Vascular Diseases: Implications and Therapeutic Potential Beyond Protein Folding (43 citations)
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) (38 citations)
- Robust lysosomal calcium signaling through channel TRPML1 is impaired by lysosomal lipid accumulation (24 citations)
In his most recent research, the most cited papers focused on:
Steven J. Fliesler mainly focuses on Retina, Retinal, Western blot, Cell biology and Photoreceptor outer segment.
His work on Retinal degeneration as part of general Retina study is frequently connected to Smith–Lemli–Opitz syndrome, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
His research integrates issues of Oxidative stress, Opsin, Molecular biology and Blot in his study of Western blot.
His study explores the link between Cell biology and topics such as Retinal pigment epithelium that cross with problems in Cell type, Viability assay, HMG-CoA reductase, Sterol and Ganglion cell layer.
His studies deal with areas such as Rhodopsin, Glycosylation, Vacuolization and Retinitis pigmentosa as well as Photoreceptor outer segment.
His Internal medicine study incorporates themes from Unfolded protein response and Macular degeneration.
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