World's Best Scientists 2026 revealed!
Bruce A. Sullenger

Bruce A. Sullenger

D-Index & Metrics

Molecular Biology

D-Index
72
Citations
19713
World Ranking
1314
National Ranking
673

Research.com Recognitions

  • 2018 - Fellow, National Academy of Inventors
  • 2014 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Bruce A. Sullenger is affiliated with Duke University in the United States. Their research encompasses a wide range of topics primarily within Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions to several subfields including Molecular Biology, Immunology, Infectious Diseases, Hematology, and Pulmonary and Respiratory Medicine.

The scientist's recent published papers include the following:

  • Design of therapeutic biomaterials to control inflammation, 2022, Nature Reviews Materials
  • Ischemic stroke in COVID-19-positive patients: an overview of SARS-CoV-2 and thrombotic mechanisms for the neurointerventionalist, 2020, Journal of NeuroInterventional Surgery
  • DAMPs/PAMPs induce monocytic TLR activation and tolerance in COVID-19 patients; nucleic acid binding scavengers can counteract such TLR agonists, 2022, Biomaterials
  • Multiplexed, quantitative serological profiling of COVID-19 from blood by a point-of-care test, 2021, Science Advances
  • PEG-Like Brush Polymer Conjugate of RNA Aptamer That Shows Reversible Anticoagulant Activity and Minimal Immune Response, 2022, Advanced Materials

Their frequent co-authors include:

  • Lyra B. Olson
  • Ibtehaj A. Naqvi
  • Haixiang Yu
  • Bryan Kraft
  • Smita K. Nair

Bruce A. Sullenger has consistently published in several key venues, with multiple publications in the following journals:

  • Molecular Therapy - Nucleic Acids
  • Nucleic Acid Therapeutics
  • Stroke
  • UNC Libraries
  • Science Advances

The main topics covered in their work include:

  • Advanced biosensing and bioanalysis techniques
  • RNA Interference and Gene Delivery
  • Blood Coagulation and Thrombosis Mechanisms
  • COVID-19 Clinical Research Studies
  • Immune cells in cancer
  • CRISPR and Genetic Engineering
  • Heparin-Induced Thrombocytopenia and Thrombosis

Awards received by this scientist include:

  • Fellow, National Academy of Inventors, 2018
  • Fellow of the American Association for the Advancement of Science (AAAS), 2014

Best Publications

  • Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras.

    James O McNamara;Eran R Andrechek;Yong Wang;Kristi D Viles

  • Aptamers: An Emerging Class of Therapeutics

    Shahid M Nimjee;Christopher P Rusconi;Bruce A Sullenger

  • Overexpression of TAR sequences renders cells resistant to human immunodeficiency virus replication

    Bruce A. Sullenger;Humilidad F. Gallardo;Grace E. Ungers;Eli Gilboa

  • In vivo activity of nuclease-resistant siRNAs.

    Juliana M. Layzer;Anton P. Mccaffrey;Alice K. Tanner;Zan Huang

  • Notch promotes radioresistance of glioma stem cells

    Jialiang Wang;Timothy P. Wakeman;Justin D. Lathia;Anita B. Hjelmeland

  • RNA aptamers as reversible antagonists of coagulation factor IXa.

    Christopher P. Rusconi;Elizabeth Scardino;Juliana Layzer;George A. Pitoc

  • Emerging clinical applications of RNA

    Bruce A. Sullenger;Eli Gilboa

  • Aptamers as Therapeutics

    Shahid M. Nimjee;Rebekah R. White;Richard C. Becker;Bruce A. Sullenger

  • Antidote-mediated control of an anticoagulant aptamer in vivo.

    Christopher P Rusconi;Joseph D Roberts;George A Pitoc;Shahid M Nimjee

  • Developing aptamers into therapeutics

    Rebekah R. White;Bruce A. Sullenger;Christopher P. Rusconi

  • Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice

    James O. McNamara;Despina Kolonias;Fernando Pastor;Robert S. Mittler

  • Generation of Species Cross-reactive Aptamers Using “Toggle” SELEX

    Rebekah White;Christopher Rusconi;Elizabeth Scardino;Alisa Wolberg

  • Ribozyme-mediated repair of defective mRNA by targeted trans -splicing

    Bruce A. Sullenger;Thomas R. Cech

  • From the RNA world to the clinic.

    Bruce A. Sullenger;Smita Nair

  • In vivo selection of tumor-targeting RNA motifs

    Jing Mi;Yingmiao Liu;Zahid N Rabbani;Zhongguang Yang

  • Gene therapy progress and prospects: RNA aptamers

    N S Que-Gewirth;B A Sullenger

  • Pre-existing anti-polyethylene glycol antibody linked to first-exposure allergic reactions to pegnivacogin, a PEGylated RNA aptamer.

    Nancy J. Ganson;Thomas J. Povsic;Bruce A. Sullenger;John H. Alexander

  • Improved gene expression upon transfer of the adenosine deaminase minigene outside the transcriptional unit of a retroviral vector.

    Petros A. Hantzopoulos;Bruce A. Sullenger;Grace Ungers;Eli Gilboa

  • Tethering ribozymes to a retroviral packaging signal for destruction of viral RNA

    Bruce A. Sullenger;Thomas R. Cech

  • Ribozyme-Mediated Repair of Sickle β-Globin mRNAs in Erythrocyte Precursors

    Ning Lan;Richard P. Howrey;Seong-Wook Lee;Clayton A. Smith

Frequent Co-Authors

Smita Nair
Smita Nair Duke University
Richard C. Becker
Richard C. Becker University of Cincinnati
Eli Gilboa
Eli Gilboa University of Miami
Kam W. Leong
Kam W. Leong Columbia University
David S. Pisetsky
David S. Pisetsky Duke University
Joseph R. Nevins
Joseph R. Nevins Duke University
Sriram Krishnaswamy
Sriram Krishnaswamy Children's Hospital of Philadelphia
James O McNamara
James O McNamara Duke University
Mark W. Dewhirst
Mark W. Dewhirst Duke University
Daniel J. George
Daniel J. George Duke University

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