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Biology and Biochemistry

D-Index
57
Citations
10071
World Ranking
13991
National Ranking
5908

Overview

Yuko Kawakami is affiliated with the La Jolla Institute For Allergy & Immunology in the United States. Their research spans multiple aspects of immunology, with a focus on mast cells, allergy mechanisms, and immune cell function.

The main fields of study for Kawakami include Medicine and Immunology and Microbiology, with significant attention to subfields such as Immunology, Physiology, Immunology and Allergy, Dermatology, and Surgery. The scientist's research topics prominently feature:

  • Mast cells and histamine
  • Allergic Rhinitis and Sensitization
  • Asthma and respiratory diseases
  • Dermatology and Skin Diseases
  • Immune Cell Function and Interaction
  • Urticaria and Related Conditions
  • Polyamine Metabolism and Applications

Kawakami has published extensively in several venues, with a notable concentration in Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, contributing nine publications there. Other publication venues include The Journal of Immunology, JCI Insight, npj Regenerative Medicine, and Internal Medicine.

Recent papers include:

  • Cooperative Regulation of the Mucosal Mast Cell-Specific Protease Genes Mcpt1 and Mcpt2 by GATA and Smad Transcription Factors, 2020, The Journal of Immunology
  • Dendritic cell immunoreceptor drives atopic dermatitis by modulating oxidized CaMKII-involved mast cell activation, 2022, JCI Insight
  • Immunomodulatory contribution of mast cells to the regenerative biomaterial microenvironment, 2023, npj Regenerative Medicine
  • Short-term Change in Resting Energy Expenditure and Body Compositions in Therapeutic Process for Graves' Disease, 2020, Internal Medicine
  • Novel inhibitors of histamine-releasing factor suppress food allergy in a murine model, 2021, Allergology International

Frequent collaborators in Kawakami's research include Toshiaki Kawakami, Yu Kawakami, Kazumi Kasakura, Takahiro Arai, and Tomoaki Ando.

Best Publications

  • PKC-beta controls I kappa B kinase lipid raft recruitment and activation in response to BCR signaling.

    Thomas T. Su;Beichu Guo;Yuko Kawakami;Karen Sommer

  • The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C

    Libo Yao;Yuko Kawakami;Toshiaki Kawakami

  • Regulation of mast cell survival by IgE.

    Koichi Asai;Jiro Kitaura;Yuko Kawakami;Noboru Yamagata

  • Involvement of Bruton's Tyrosine Kinase in FcεRI-dependent Mast Cell Degranulation and Cytokine Production

    Daisuke Hata;Yuko Kawakami;Naoki Inagaki;Chris S. Lantz

  • Mast cells in atopic dermatitis.

    Toshiaki Kawakami;Tomoaki Ando;Miho Kimura;Bridget S Wilson

  • Evidence that IgE molecules mediate a spectrum of effects on mast cell survival and activation via aggregation of the FcεRI

    Jiro Kitaura;Jinming Song;Mindy Tsai;Koichi Asai

  • Tyrosine phosphorylation and activation of Bruton tyrosine kinase upon Fc epsilon RI cross-linking.

    Y Kawakami;L Yao;T Miura;S Tsukada

  • CD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the Tec family kinase ITK/EMT in the human Jurkat leukemic T-cell line

    Avery August;Spencer Gibson;Yuko Kawakami;Toshiaki Kawakami

  • Akt-dependent cytokine production in mast cells.

    Jiro Kitaura;Koichi Asai;Mari Maeda-Yamamoto;Yuko Kawakami

  • Protein Kinase C βII Regulates Akt Phosphorylation on Ser-473 in a Cell Type- and Stimulus-specific Fashion

    Yuko Kawakami;Hajime Nishimoto;Jiro Kitaura;Mari Maeda-Yamamoto

  • Bruton’s tyrosine kinase regulates apoptosis and JNK/SAPK kinase activity

    Yuko Kawakami;Toru Miura;Reid Bissonnette;Daisuke Hata

  • Redundant and opposing functions of two tyrosine kinases, Btk and Lyn, in mast cell activation.

    Yuko Kawakami;Jiro Kitaura;Anne B. Satterthwaite;Roberta M. Kato

  • Positive and Negative Regulation of Mast Cell Activation by Lyn via the FcεRI

    Wenbin Xiao;Hajime Nishimoto;Hong Hong;Jiro Kitaura

  • O-Methylated Catechins from Tea Leaves Inhibit Multiple Protein Kinases in Mast Cells

    Mari Maeda-Yamamoto;Naoki Inagaki;Jiro Kitaura;Takao Chikumoto

  • PKCβ modulates antigen receptor signaling via regulation of Btk membrane localization

    Shin W. Kang;Matthew I. Wahl;Julia Chu;Jiro Kitaura

  • Pleckstrin Homology Domains Interact with Filamentous Actin

    Libo Yao;Paul Janmey;Luciano G. Frigeri;Wei Han

  • Structure and Expression of Novel Protein-Tyrosine Kinases, EMB and EMT, in Hematopoietic Cells

    Nobuo Yamada;Yuko Kawakami;Hitoshi Kimura;Hiromi Fukamachi

  • Multiple Signaling Pathways for the Activation of JNK in Mast Cells: Involvement of Bruton’s Tyrosine Kinase, Protein Kinase C, and JNK Kinases, SEK1 and MKK7

    Yuko Kawakami;Stephen E. Hartman;Pamela M. Holland;Jonathan A. Cooper

  • IgE- and IgE+Ag-mediated mast cell migration in an autocrine/paracrine fashion

    Jiro Kitaura;Tatsuya Kinoshita;Masaaki Matsumoto;Shaun Chung

  • Interactions between protein kinase C and pleckstrin homology domains. Inhibition by phosphatidylinositol 4,5-bisphosphate and phorbol 12-myristate 13-acetate.

    Libo Yao;Hidefumi Suzuki;Koichiro Ozawa;Jianbei Deng

Frequent Co-Authors

Toshiaki Kawakami
Toshiaki Kawakami University of California, San Diego
Clifford A. Lowell
Clifford A. Lowell University of California, San Francisco
Kenji Matsumoto
Kenji Matsumoto Izumi Municipal Hospital
Stephen J. Galli
Stephen J. Galli Stanford University
David J. Rawlings
David J. Rawlings Seattle Children's Hospital
Michael Croft
Michael Croft La Jolla Institute For Allergy & Immunology
Michael Leitges
Michael Leitges University of Oslo
Naoki Inagaki
Naoki Inagaki Gifu Pharmaceutical University
Chisei Ra
Chisei Ra Nihon University
Gordon B. Mills
Gordon B. Mills Oregon Health & Science University

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