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Anumantha G. Kanthasamy

Anumantha G. Kanthasamy

D-Index & Metrics

Biology and Biochemistry

D-Index
83
Citations
46778
World Ranking
3421
National Ranking
1724

Research.com Recognitions

  • 2015 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Anumantha G. Kanthasamy is affiliated with the University of Georgia in the United States and specializes in research at the intersection of medicine, biochemistry, genetics, molecular biology, and neuroscience. Their scholarly contributions primarily address mechanisms underlying neurological disorders and treatments, with a marked focus on Parkinson's disease and neuroinflammation.

Their recent scholarly work includes several research articles published in notable scientific journals. Among these are "Blinded RT-QuIC Analysis of α-Synuclein Biomarker in Skin Tissue From Parkinson's Disease Patients" (2020) published in Movement Disorders, "Kv1.3 modulates neuroinflammation and neurodegeneration in Parkinson's disease" (2020) appearing in the Journal of Clinical Investigation, and "Molecular Signatures of Neuroinflammation Induced by αSynuclein Aggregates in Microglial Cells" (2020) published in Frontiers in Immunology. Other recent papers include "Impact of Environmental Risk Factors on Mitochondrial Dysfunction, Neuroinflammation, Protein Misfolding, and Oxidative Stress in the Etiopathogenesis of Parkinson's Disease" (2022) from the International Journal of Molecular Sciences and "Mechanistic Insights Into Gut Microbiome Dysbiosis-Mediated Neuroimmune Dysregulation and Protein Misfolding and Clearance in the Pathogenesis of Chronic Neurodegenerative Disorders" (2022) published in Frontiers in Neuroscience.

Kanthasamy's frequent coauthors consist of:

  • Arthi Kanthasamy
  • Huajun Jin
  • Vellareddy Anantharam
  • Gary Zenitsky
  • Adhithiya Charli

Their work is often published in recurring venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • International Journal of Molecular Sciences
  • Frontiers in Cellular Neuroscience
  • Frontiers in Immunology
  • Frontiers in Neuroscience

Kanthasamy's research spans several main fields including:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology
  • Neuroscience

Within these areas, notable subfields of study are:

  • Neurology
  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Physiology
  • Immunology

The primary topics addressed in their research include:

  • Parkinson's Disease Mechanisms and Treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Alzheimer's disease research and treatments
  • Nuclear Receptors and Signaling
  • Neurological disorders and treatments
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Nerve injury and regeneration

Kanthasamy has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS) since 2015.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice

    Richard Gordon;Eduardo A. Albornoz;Daniel C. Christie;Monica R. Langley

  • Gut microbiome in health and disease: Linking the microbiome-gut-brain axis and environmental factors in the pathogenesis of systemic and neurodegenerative diseases.

    Shivani Ghaisas;Joshua Maher;Anumantha Kanthasamy

  • Mechanism of intranasal drug delivery directly to the brain.

    Tyler P. Crowe;M. Heather West Greenlee;Anumantha G. Kanthasamy;Walter H. Hsu

  • Neurotoxicity of pesticides.

    Jason R Richardson;Vanessa Fitsanakis;Remco H S Westerink;Anumantha G Kanthasamy

  • Mitochondria-targeted antioxidants for treatment of Parkinson's disease: preclinical and clinical outcomes.

    Huajun Jin;Arthi Kanthasamy;Anamitra Ghosh;Vellareddy Anantharam

  • Caspase-3-Dependent Proteolytic Cleavage of Protein Kinase Cδ Is Essential for Oxidative Stress-Mediated Dopaminergic Cell Death after Exposure to Methylcyclopentadienyl Manganese Tricarbonyl

    Vellareddy Anantharam;Masashi Kitazawa;Jarrad Wagner;Siddharth Kaul

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Dieldrin-induced neurotoxicity: relevance to Parkinson's disease pathogenesis.

    Anumantha G. Kanthasamy;Masashi Kitazawa;Arthi Kanthasamy;Vellareddy Anantharam

  • Caspase-3 dependent proteolytic activation of protein kinase C delta mediates and regulates 1-methyl-4-phenylpyridinium (MPP+)-induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration.

    Siddharth Kaul;Arthi Kanthasamy;Masashi Kitazawa;Vellareddy Anantharam

  • Environmental neurotoxic pesticide increases histone acetylation to promote apoptosis in dopaminergic neuronal cells: relevance to epigenetic mechanisms of neurodegeneration.

    Chunjuan Song;Arthi Kanthasamy;Vellareddy Anantharam;Faneng Sun

  • Neuroprotection by a mitochondria-targeted drug in a Parkinson's disease model

    Anamitra Ghosh;Karunakaran Chandran;Shasi V. Kalivendi;Joy Joseph

  • Mitochondrial impairment in microglia amplifies NLRP3 inflammasome proinflammatory signaling in cell culture and animal models of Parkinson's disease.

    Souvarish Sarkar;Emir Malovic;Dilshan S. Harishchandra;Dilshan S. Harishchandra;Shivani Ghaisas;Shivani Ghaisas

  • Dieldrin-induced oxidative stress and neurochemical changes contribute to apoptopic cell death in dopaminergic cells.

    Masashi Kitazawa;Vellareddy Anantharam;Anumantha G. Kanthasamy

  • Manganese-Induced Neurotoxicity: New Insights Into the Triad of Protein Misfolding, Mitochondrial Impairment, and Neuroinflammation.

    Dilshan S. Harischandra;Shivani Ghaisas;Gary Zenitsky;Huajun Jin

  • Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia.

    Nikhil Panicker;Nikhil Panicker;Souvarish Sarkar;Dilshan S. Harischandra;Matthew Neal

  • Environmental neurotoxin dieldrin induces apoptosis via caspase-3-dependent proteolytic activation of protein kinase C delta (PKCdelta): Implications for neurodegeneration in Parkinson's disease

    Anumantha G Kanthasamy;Masashi Kitazawa;Yongjie Yang;Vellareddy Anantharam

Frequent Co-Authors

Vellareddy Anantharam
Vellareddy Anantharam Iowa State University
Arthi Kanthasamy
Arthi Kanthasamy Iowa State University
Balaraman Kalyanaraman
Balaraman Kalyanaraman Medical College of Wisconsin
Balaji Narasimhan
Balaji Narasimhan Iowa State University
Sergio Lavandero
Sergio Lavandero University of Chile
Joy Joseph
Joy Joseph Medical College of Wisconsin
Evelina Gatti
Evelina Gatti Aix-Marseille University
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center
Steven Finkbeiner
Steven Finkbeiner University of California, San Francisco
Shazib Pervaiz
Shazib Pervaiz National University of Singapore

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