Vellareddy Anantharam

Overview

Best Publications

• Guidelines for the use and interpretation of assays for monitoring autophagy

  Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  8665
  Citations

• Mitochondria-targeted antioxidants for treatment of Parkinson's disease: preclinical and clinical outcomes.

  Huajun Jin;Arthi Kanthasamy;Anamitra Ghosh;Vellareddy Anantharam

  374
  Citations

• Caspase-3-Dependent Proteolytic Cleavage of Protein Kinase Cδ Is Essential for Oxidative Stress-Mediated Dopaminergic Cell Death after Exposure to Methylcyclopentadienyl Manganese Tricarbonyl

  Vellareddy Anantharam;Masashi Kitazawa;Jarrad Wagner;Siddharth Kaul

  319
  Citations

• Oxalate:formate exchange. The basis for energy coupling in Oxalobacter.

  Vellareddy Anantharam;M. J. Allison;P. C. Maloney

  265
  Citations

• Dieldrin-induced neurotoxicity: relevance to Parkinson's disease pathogenesis.

  Anumantha G. Kanthasamy;Masashi Kitazawa;Arthi Kanthasamy;Vellareddy Anantharam

  245
  Citations

• Caspase-3 dependent proteolytic activation of protein kinase C delta mediates and regulates 1-methyl-4-phenylpyridinium (MPP+)-induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration.

  Siddharth Kaul;Arthi Kanthasamy;Masashi Kitazawa;Vellareddy Anantharam

  244
  Citations

• Environmental neurotoxic pesticide increases histone acetylation to promote apoptosis in dopaminergic neuronal cells: relevance to epigenetic mechanisms of neurodegeneration.

  Chunjuan Song;Arthi Kanthasamy;Vellareddy Anantharam;Faneng Sun

  242
  Citations

• Dieldrin induces apoptosis by promoting caspase-3-dependent proteolytic cleavage of protein kinase Cδ in dopaminergic cells: Relevance to oxidative stress and dopaminergic degeneration

  M. Kitazawa;V. Anantharam;A.G. Kanthasamy

  233
  Citations

• Mitochondrial impairment in microglia amplifies NLRP3 inflammasome proinflammatory signaling in cell culture and animal models of Parkinson's disease.

  Souvarish Sarkar;Emir Malovic;Dilshan S. Harishchandra;Dilshan S. Harishchandra;Shivani Ghaisas;Shivani Ghaisas

  229
  Citations

• Dieldrin-induced oxidative stress and neurochemical changes contribute to apoptopic cell death in dopaminergic cells.

  Masashi Kitazawa;Vellareddy Anantharam;Anumantha G. Kanthasamy

  226
  Citations

• Manganese-Induced Neurotoxicity: New Insights Into the Triad of Protein Misfolding, Mitochondrial Impairment, and Neuroinflammation.

  Dilshan S. Harischandra;Shivani Ghaisas;Gary Zenitsky;Huajun Jin

  223
  Citations

• Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia.

  Nikhil Panicker;Nikhil Panicker;Souvarish Sarkar;Dilshan S. Harischandra;Matthew Neal

  198
  Citations

• Protein kinase Cdelta is a key downstream mediator of manganese-induced apoptosis in dopaminergic neuronal cells.

  Calivarathan Latchoumycandane;Vellareddy Anantharam;Masashi Kitazawa;Yongjie Yang

  191
  Citations

• α-Synuclein negatively regulates protein kinase Cδ expression to suppress apoptosis in dopaminergic neurons by reducing p300 histone acetyltransferase activity.

  Huajun Jin;Arthi Kanthasamy;Anamitra Ghosh;Yongjie Yang

  191
  Citations

• Neuroprotective effect of protein kinase C delta inhibitor rottlerin in cell culture and animal models of Parkinson's disease.

  Danhui Zhang;Vellareddy Anantharam;Arthi Kanthasamy;Anumantha G. Kanthasamy

  187
  Citations

• Molecular mechanisms underlying protective effects of quercetin against mitochondrial dysfunction and progressive dopaminergic neurodegeneration in cell culture and MitoPark transgenic mouse models of Parkinson's Disease

  Muhammet Ay;Jie Luo;Monica Langley;Huajun Jin

  180
  Citations

• Role of proteolytic activation of protein kinase Cdelta in oxidative stress-induced apoptosis.

  Anumantha G. Kanthasamy;Masashi Kitazawa;Arthi Kanthasamy;Vellareddy Anantharam

  171
  Citations

• Ethanol Inhibition of Recombinant Heteromeric NMDA Channels in the Presence and Absence of Modulators

  Benson Chu;Vellareddy Anantharam;Steven N. Treistman

  166
  Citations

• Pharmacological inhibition of neuronal NADPH oxidase protects against 1-methyl-4-phenylpyridinium (MPP+)-induced oxidative stress and apoptosis in mesencephalic dopaminergic neuronal cells.

  Vellareddy Anantharam;Siddharth Kaul;Chunjuan Song;Arthi Kanthasamy

  166
  Citations

• Environmental neurotoxin dieldrin induces apoptosis via caspase-3-dependent proteolytic activation of protein kinase C delta (PKCdelta): Implications for neurodegeneration in Parkinson's disease

  Anumantha G Kanthasamy;Masashi Kitazawa;Yongjie Yang;Vellareddy Anantharam

  94
  Citations